PANTHER Gene Information

Gene Symbol(s):

CCL8

Organism:

Pan troglodytes

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Gene Name:

C-C motif chemokine

Gene ID:

ENSPTRG00000009002.3

Protein ID:

H2QCN5

Persistent Id:

PTN000245984

Alternate Ids:

114668174(GI)	ENSPTRG00000009002(Ensembl)
H2QCN5_PANTR(UniProtKB-ID)	XM_523600(refSeq)
ENSPTRP00000015356(Ensembl_PRO)	468209(GeneID)
H2QCN5(Synonym)	ENSPTRT00000016591(Ensembl_TRS)
AACZ04043905(EMBL)
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PANTHER Classification

PANTHER Family:	SMALL INDUCIBLE CYTOKINE A (PTHR12015)
PANTHER Subfamily:	C-C MOTIF CHEMOKINE 8 (PTHR12015:SF209)
PANTHER GO-slim Molecular Function:	cytokine activity chemokine receptor binding
PANTHER GO-slim Biological Process:	positive regulation of GTPase activity leukocyte chemotaxis positive regulation of cell migration G protein-coupled receptor signaling pathway cytokine-mediated signaling pathway granulocyte migration inflammatory response antimicrobial humoral immune response mediated by antimicrobial peptide
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	cytokine

Pathway Categories:

Inflammation mediated by chemokine and cytokine signaling pathway

Chemokine

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	CCR chemokine receptor binding, protein kinase activity, heparin binding, cytokine activity, chemokine activity, phospholipase activator activity
GO BP Complete:	chemotaxis, inflammatory response, immune response, negative regulation by host of viral genome replication, eosinophil chemotaxis, chemokine-mediated signaling pathway, calcium ion transport, cell-cell signaling, exocytosis, intracellular calcium ion homeostasis, positive regulation of cell migration, antimicrobial humoral immune response mediated by antimicrobial peptide
GO CC Complete:	extracellular space, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10635\|UniProtKB=P80075	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000004504.3\|UniProtKB=G3QPC3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009784.4\|UniProtKB=F6Y1K4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101878\|UniProtKB=Q9Z121	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000010155\|UniProtKB=P82943	Bos taurus	O
CANLF\|Ensembl=ENSCAFG00845008998.1\|UniProtKB=A0A8I3NA82	Canis lupus familiaris	O
BOVIN\|Ensembl=ENSBTAG00000014113\|UniProtKB=Q09141	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00035063005\|UniProtKB=P49873	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000040648.2\|UniProtKB=C7F842	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000013594.6\|UniProtKB=M3WJ48	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00000023928\|UniProtKB=Q68AY9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019157.4\|UniProtKB=F7BK46	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000021072.3\|UniProtKB=F7GC54	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000002929.2\|UniProtKB=F7B281	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029956.1\|UniProtKB=E1BSX8	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010029639.1\|UniProtKB=A0A8V1ALD3	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010029641.1\|UniProtKB=A0A8V1AJN8	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010029562\|UniProtKB=Q90826	Gallus gallus	O
XENTR\|Gene=LOC101730633\|UniProtKB=A0A8J0T226	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018031.2\|UniProtKB=H2MUW3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000028881.1\|UniProtKB=A0A3B3IKJ3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110222-1\|UniProtKB=A0A2R8QR67	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-110222-2\|UniProtKB=F1QBE9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003372.1\|UniProtKB=W5M6H7	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000015297.2\|UniProtKB=H2MKE8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029097.1\|UniProtKB=A0A3B3H537	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025796.1\|UniProtKB=A0A3B3HWP0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041014-167\|UniProtKB=Q5TYQ0	Danio rerio	O
DANRE\|Ensembl=ENSDARG00000100484.2\|UniProtKB=A0A8M3AZJ3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041014-163\|UniProtKB=Q5TYP9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-140718-2\|UniProtKB=A0A0G2L2I4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041014-165\|UniProtKB=E7F787	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-131121-128\|UniProtKB=A0A0R4IFJ9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-081022-33\|UniProtKB=A9ZPD7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-041014-320\|UniProtKB=A9ZPE8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-131121-94\|UniProtKB=A9ZPD6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-131127-149\|UniProtKB=A9ZPD5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-140718-1\|UniProtKB=A9ZPD8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010172.1\|UniProtKB=W5MVN6	lepisosteus oculatus	O