PANTHER Gene Information

Gene Symbol(s):

PACSIN2

Organism:

Pan troglodytes

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Gene Name:

Protein kinase C and casein kinase substrate in neurons 2

Gene ID:

ENSPTRG00000014465.5

Protein ID:

H2QLU5

Persistent Id:

PTN000103034

Alternate Ids:

GABD01000854(EMBL)	XM_001171540(refSeq)
470231(GeneID)	114686746(GI)
ENSPTRT00000027030(Ensembl_TRS)	ENSPTRG00000014465(Ensembl)
ENSPTRP00000024917(Ensembl_PRO)	JAA32246(EMBL-CDS)
H2QLU5_PANTR(UniProtKB-ID)	H2QLU5(Synonym)
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PANTHER Classification

PANTHER Family:	PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 (PTHR23065)
PANTHER Subfamily:	PROTEIN KINASE C AND CASEIN KINASE SUBSTRATE IN NEURONS PROTEIN 2 (PTHR23065:SF14)
PANTHER GO-slim Molecular Function:	phospholipid binding
PANTHER GO-slim Biological Process:	plasma membrane organization cytoskeleton organization regulation of endocytosis
PANTHER GO-slim Cellular Component:	plasma membrane endosome
PANTHER protein class:	actin or actin-binding cytoskeletal protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	identical protein binding, lipid binding, phosphatidic acid binding, phospholipid binding, cytoskeletal protein binding, kinase activity
GO BP Complete:	plasma membrane tubulation, negative regulation of endocytosis, caveola assembly, cytoskeleton organization, protein localization to endosome, caveolin-mediated endocytosis, modulation of chemical synaptic transmission, regulation of endocytosis, actin cytoskeleton organization, cell projection morphogenesis
GO CC Complete:	nuclear speck, centriolar satellite, cell projection, plasma membrane, early endosome, caveola, endosome, cytoskeleton, cell-cell junction, cytoplasm, intracellular membrane-bounded organelle, cytosol, ruffle membrane, recycling endosome membrane, glutamatergic synapse

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8571\|UniProtKB=Q9UNF0	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000016309.3\|UniProtKB=G3RJL7	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1345153\|UniProtKB=Q9WVE8	Mus musculus	LDO
RAT\|RGD=69411\|UniProtKB=Q9QY17	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000019290.4\|UniProtKB=Q1RMR9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000036.5\|UniProtKB=A0A480MPL1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011667.4\|UniProtKB=A0A9L0T362	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010098.5\|UniProtKB=A0A337S9L8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014394.1\|UniProtKB=A0A8I3NW16	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000046272.1\|UniProtKB=A0A6I8NGD7	Ornithorhynchus anatinus	LDO
CHICK\|Gene=PACSIN2\|UniProtKB=O13154	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010012175.1\|UniProtKB=A0A8V0Y8B2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015928.3\|UniProtKB=G1KRZ9	Anolis carolinensis	LDO
XENLA\|Gene=pacsin2\|UniProtKB=Q9DDA9	Xenopus laevis	O
XENLA\|Gene=pacsin2.S\|UniProtKB=A0A8J1MNZ1	Xenopus laevis	O
XENLA\|Gene=pacsin2.L\|UniProtKB=A0A8J1MJ33	Xenopus laevis	LDO
XENTR\|Gene=pacsin2\|UniProtKB=A0A8J1J9M7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015594.2\|UniProtKB=A0A3B3IP73	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2596\|UniProtKB=A0A0R4IHF0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015131.1\|UniProtKB=W5NDB5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008003.3\|UniProtKB=A0A1W2WFB7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414577\|UniProtKB=A0A9J7L3V5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC576050\|UniProtKB=A0A7M7LW56	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018467\|UniProtKB=Q6AHQ8	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG16865\|UniProtKB=A8XPZ1	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00108383\|UniProtKB=A0A454Y2I0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0053094\|UniProtKB=A0A0B4KH28	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008046\|UniProtKB=A0A1S4GX35	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007515\|UniProtKB=D2A3I3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303168\|UniProtKB=E9FT89	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018948\|UniProtKB=B7PNV7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG156856\|UniProtKB=T1EM19	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG97481\|UniProtKB=T1G9H0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG156082\|UniProtKB=T1ELR6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g51540\|UniProtKB=A7S2R6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g229120\|UniProtKB=A7S0K6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50721\|UniProtKB=B3S5Q2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26556\|UniProtKB=A9V2Q3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26520\|UniProtKB=A9V2L9	Monosiga brevicollis	LDO
YEAST\|SGD=S000000626\|UniProtKB=P25623	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL147W\|UniProtKB=Q758D3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000174492\|UniProtKB=A0A1D8PL12	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F01694g\|UniProtKB=Q6C390	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00697\|UniProtKB=C8VRP5	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU04427\|UniProtKB=Q7RZ47	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07570\|UniProtKB=A7EQG8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02674\|UniProtKB=Q0UZZ0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC4C3.06\|UniProtKB=O43059	Schizosaccharomyces pombe	O
USTMA\|EnsemblGenome=UMAG_02358\|UniProtKB=A0A0D1E1L9	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10354\|UniProtKB=E3KKQ8	Puccinia graminis	O
YEAST\|SGD=S000001847\|UniProtKB=P43556	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR241C\|UniProtKB=Q75CY1	Eremothecium gossypii	O
CANAL\|CGD=CAL0000200127\|UniProtKB=A0A1D8PTF4	Candida albicans	O
CANAL\|CGD=CAL0000176620\|UniProtKB=A0A1D8PTI9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B15686g\|UniProtKB=Q6CEH0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E05489g\|UniProtKB=Q6C6X5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05677\|UniProtKB=Q5B1A3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G04300\|UniProtKB=Q4WGA0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09537\|UniProtKB=Q7S2C4	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03088\|UniProtKB=A7ECP9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_03668\|UniProtKB=Q0UX46	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC1952.16\|UniProtKB=Q9UUJ3	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC13A11.01c\|UniProtKB=Q09697	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01000\|UniProtKB=Q5KH74	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10913\|UniProtKB=A0A0D1DWP4	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_11096\|UniProtKB=E3KND1	Puccinia graminis	O
YEAST\|SGD=S000004635\|UniProtKB=Q05080	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABR082W\|UniProtKB=Q75DE5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000193415\|UniProtKB=Q59UQ6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E29557g\|UniProtKB=Q6C455	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04963\|UniProtKB=Q5B3B7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G10250\|UniProtKB=Q4WXP7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU10905\|UniProtKB=A7UWG5	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_06645\|UniProtKB=A7EMU6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_08413\|UniProtKB=Q0UIK1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC20G8.05c\|UniProtKB=Q09822	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03596\|UniProtKB=B6K4N4	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPBC11C11.02\|UniProtKB=Q10199	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04077\|UniProtKB=B6K5V1	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNK00960\|UniProtKB=Q5K9S2	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNB00620\|UniProtKB=Q5KMS8	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00168\|UniProtKB=A0A0D1EBL3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_16937\|UniProtKB=E3L3F0	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_16936\|UniProtKB=E3L3E9	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_21447\|UniProtKB=H6QRG1	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_90049\|UniProtKB=F4P6T8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92106\|UniProtKB=F4PCY6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_36867\|UniProtKB=F4P0Q6	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33239\|UniProtKB=F4P3D9	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_110690\|UniProtKB=C4LUB6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_065490\|UniProtKB=B1N368	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_105210\|UniProtKB=C4M126	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_148050\|UniProtKB=C4LSX5	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0274695\|UniProtKB=Q555L8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48387\|UniProtKB=F0ZNY9	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0290233\|UniProtKB=Q54GD0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_155654\|UniProtKB=F0ZUK4	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0271676\|UniProtKB=Q75JD4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92017\|UniProtKB=F0ZKM3	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0271812\|UniProtKB=Q55AN3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152774\|UniProtKB=F0ZM88	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00033091001\|UniProtKB=A0BXH1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000311001\|UniProtKB=A0BBF9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025956001\|UniProtKB=A0EE94	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019613001\|UniProtKB=A0DS92	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003632001\|UniProtKB=A0E652	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=PTMB.209\|UniProtKB=Q6BG14	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021727001\|UniProtKB=A0DZU2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036084001\|UniProtKB=A0C836	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011037001\|UniProtKB=A0CVQ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016341001\|UniProtKB=A0DEP8	Paramecium tetraurelia	O
PHYRM\|Gene=H3GW87_PHYRM\|UniProtKB=H3GW87	Phytophthora ramorum	O
PHYRM\|Gene=H3HBN7_PHYRM\|UniProtKB=H3HBN7	Phytophthora ramorum	O