PANTHER Gene Information

Gene Symbol(s):

NR1D2

Organism:

Pan troglodytes

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Gene Name:

Nuclear receptor subfamily 1 group D member 2

Gene ID:

ENSPTRG00000014696.6

Protein ID:

A0A2I3S658

Persistent Id:

PTN000638129

Alternate Ids:

A0A2I3S658_PANTR(UniProtKB-ID)	ENSPTRP00000072046(Ensembl_PRO)
ENSPTRG00000014696(Ensembl)	AACZ04000177(EMBL)
ENSPTRT00000091168(Ensembl_TRS)	A0A2I3S658(Synonym)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2 (PTHR24082:SF112)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II cell differentiation hormone-mediated signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, sequence-specific double-stranded DNA binding
GO BP Complete:	negative regulation of inflammatory response, lipid homeostasis, regulation of DNA-templated transcription, circadian behavior, regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, hormone-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, cell differentiation, energy homeostasis, regulation of inflammatory response, regulation of lipid metabolic process, regulation of skeletal muscle cell differentiation, intracellular receptor signaling pathway
GO CC Complete:	nucleus, cytoplasm, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7963\|UniProtKB=Q14995	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000003222.3\|UniProtKB=A0A2I2ZPR1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022240.4\|UniProtKB=H9EUD4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2449205\|UniProtKB=Q60674	Mus musculus	LDO
RAT\|RGD=628828\|UniProtKB=Q63504	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000018024.6\|UniProtKB=F1MWI2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000027017.3\|UniProtKB=I3LL46	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000007646.4\|UniProtKB=F7C3L4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027540.4\|UniProtKB=M3XD13	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019679.1\|UniProtKB=A0A8I3PFC6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014892.4\|UniProtKB=F7GGA4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045456.1\|UniProtKB=A0A6I8P5E9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024675.1\|UniProtKB=A0A8V1A1C9	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010001528.1\|UniProtKB=A0A8V0XBR1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011374.4\|UniProtKB=H9GHL2	Anolis carolinensis	LDO
XENLA\|Gene=LOC108718924\|UniProtKB=A0A1L8FW92	Xenopus laevis	O
XENLA\|Gene=LOC108719956\|UniProtKB=A0A1L8FRD7	Xenopus laevis	LDO
XENTR\|Gene=nr1d2\|UniProtKB=A0A8J0QGR6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016431.2\|UniProtKB=H2MPB6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024060.1\|UniProtKB=A0A3B3HUT5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-244\|UniProtKB=Q6GMI3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006818.1\|UniProtKB=W5MIQ1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002352.3\|UniProtKB=F6PJI0	Ciona intestinalis	O
BRAFL\|Gene=LOC118405633\|UniProtKB=A0A9J7HNG2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100890792\|UniProtKB=A0A7M7N311	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC756187\|UniProtKB=A0A7M7N296	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580686\|UniProtKB=A0A7M7RE14	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592902\|UniProtKB=A0A7M7RHM5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100887874\|UniProtKB=A0A7M7GN36	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576385\|UniProtKB=A0A7M7P366	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917889\|UniProtKB=A0A7M7PPV4	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O