The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

CDC42EP3

Organism:

Pan troglodytes

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Tree

Gene Name:

CDC42 effector protein (Rho GTPase binding) 3

Gene ID:

ENSPTRG00000052497.1

Protein ID:

G2HF05

Persistent Id:

PTN000394037

Alternate Ids:

AK305319(EMBL)	JAA42187(EMBL-CDS)
ENSPTRT00000077572(Ensembl_TRS)	G2HF05(Synonym)
459161(GeneID)	ENSPTRP00000093121(Ensembl_PRO)
350537625(GI)	XP_016798663(refSeq)
ENSPTRG00000052497(Ensembl)	G2HF05_PANTR(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CDC42 EFFECTOR PROTEIN BORG (PTHR15344)
PANTHER Subfamily:	CDC42 EFFECTOR PROTEIN 3 (PTHR15344:SF3)
PANTHER GO-slim Molecular Function:	small GTPase binding
PANTHER GO-slim Biological Process:	regulation of actin filament polymerization positive regulation of protein polymerization positive regulation of organelle organization Rho protein signal transduction regulation of cell shape regulation of plasma membrane bounded cell projection assembly
PANTHER GO-slim Cellular Component:	cytoskeleton plasma membrane cytoplasm
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	small GTPase binding
GO BP Complete:	regulation of cell shape, positive regulation of pseudopodium assembly, positive regulation of actin filament polymerization, Rho protein signal transduction
GO CC Complete:	cytoskeleton, cytoplasm, actin cytoskeleton, endomembrane system, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

-

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16943\|UniProtKB=Q9UKI2	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000043915.1\|UniProtKB=A0A2I2ZB00	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000052788.1\|UniProtKB=F6PS82	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2384718\|UniProtKB=Q9CQC5	Mus musculus	LDO
RAT\|RGD=1305858\|UniProtKB=Q0VGK8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000023736.4\|UniProtKB=Q2KI46	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000021359.4\|UniProtKB=F1S4Q9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022741.3\|UniProtKB=F6VU60	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015772.4\|UniProtKB=M3XAY8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019687.1\|UniProtKB=A0A8I3P789	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008346.4\|UniProtKB=F7EKQ1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004753.3\|UniProtKB=F7G0D8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010080.1\|UniProtKB=E1C7B1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008527.3\|UniProtKB=G1KHW2	Anolis carolinensis	LDO
XENLA\|Gene=cdc42ep3.S\|UniProtKB=A0A1L8G1Z5	Xenopus laevis	O
XENLA\|Gene=cdc42ep3.L\|UniProtKB=Q5U4S1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1015015\|UniProtKB=Q28CX6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000000835.2\|UniProtKB=H2L5F2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040912-89\|UniProtKB=Q66HU1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016572.1\|UniProtKB=W5NIL0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020428.1\|UniProtKB=H2XKU1	Ciona intestinalis	O