PANTHER Gene Information   
Gene Symbol(s): SIN3A
Organism: Sus scrofa
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Gene Name: Paired amphipathic helix protein Sin3a
Gene ID: ENSSSCG00000001880.5
Protein ID: F1SJ69
Persistent Id: PTN001389840
Alternate Ids:
HCZ88739(EMBL-CDS) F1SJ69(Synonym)
DQIR01033264(EMBL) ENSSSCG00005003508(Ensembl)
XP_013833514(refSeq) F1SJ69_PIG(UniProtKB-ID)
ENSSSCP00005003367(Ensembl_PRO) 100621221(GeneID)
927159008(GI) ENSSSCT00005005817(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: SIN3B-RELATED (PTHR12346)
PANTHER Subfamily: PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A (PTHR12346:SF2)  
PANTHER GO-slim Molecular Function: transcription corepressor activity
PANTHER GO-slim Biological Process: negative regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: Sin3-type complex
PANTHER protein class: chromatin/chromatin-binding, or -regulatory protein
Pathway Categories: p53 pathway
   Histone deacetylase complex subunit Sin3
Huntington disease
   Histone deacetylase complex subunit Sin3a

GO MF Complete: DNA binding, RNA polymerase II-specific DNA-binding transcription factor binding, transcription corepressor activity, transcription regulator inhibitor activity, chromatin binding
GO BP Complete: negative regulation of protein localization to nucleus, DNA replication, protein localization, positive regulation of neuron differentiation, positive regulation of defense response to virus by host, hematopoietic progenitor cell differentiation, negative regulation of circadian rhythm, cerebral cortex neuron differentiation, type I interferon-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, regulation of axon extension, in utero embryonic development, activation of innate immune response, response to methylglyoxal, cellular response to glucose stimulus, heterochromatin formation, negative regulation of apoptotic process, positive regulation of G2/M transition of mitotic cell cycle
GO CC Complete: transcription repressor complex, kinetochore, chromatin, Sin3-type complex
Reactome Pathways: Metabolism, Transcriptional Regulation by MECP2, RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function, SUMOylation, Metabolism of proteins, Post-translational protein modification, Gene expression (Transcription), Metabolism of lipids, Regulation of lipid metabolism by PPARalpha, Generic Transcription Pathway, Transcriptional regulation by RUNX1, SUMO E3 ligases SUMOylate target proteins, SUMOylation of transcription cofactors, Regulation of MECP2 expression and activity, RNA Polymerase II Transcription