PANTHER Gene Information   
Gene Symbol(s): AR
Organism: Sus scrofa
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Gene Name: Androgen receptor
Gene ID: ENSSSCG00000012371.5
Protein ID: F1RTM6
Persistent Id: PTN008485826
Alternate Ids:
397582(GeneID) 927218910(GI)
ENSSSCT00000013528(Ensembl_TRS) ENSSSCP00000013166(Ensembl_PRO)
HCZ88820(EMBL-CDS) F1RTM6(Synonym)
ENSSSCG00000012371(Ensembl) DQIR01033345(EMBL)
F1RTM6_PIG(UniProtKB-ID) XP_013841681(refSeq)
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PANTHER Classification
PANTHER Family: KNIRPS-RELATED PROTEIN-RELATED (PTHR48092)
PANTHER Subfamily: ANDROGEN RECEPTOR (PTHR48092:SF13)  
PANTHER GO-slim Molecular Function: RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
signaling receptor activity
PANTHER GO-slim Biological Process: positive regulation of transcription by RNA polymerase II
male gonad development
PANTHER GO-slim Cellular Component: chromatin
nucleus
PANTHER protein class: C4 zinc finger nuclear receptor
Pathway Categories: Gonadotropin-releasing hormone receptor pathway
   AR

GO MF Complete: zinc ion binding, estrogen response element binding, RNA polymerase II core promoter sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, androgen binding, chromatin binding, steroid binding, beta-catenin binding, signaling receptor binding, transcription coactivator binding, RNA polymerase II-specific DNA-binding transcription factor binding, nuclear receptor activity, POU domain binding, RNA polymerase II general transcription initiation factor binding, molecular condensate scaffold activity, ATPase binding
GO BP Complete: multicellular organism growth, positive regulation of integrin biosynthetic process, regulation of prostatic bud formation, prostate gland epithelium morphogenesis, male gonad development, regulation of systemic arterial blood pressure, negative regulation of integrin biosynthetic process, transcription by RNA polymerase II, positive regulation of epithelial cell proliferation involved in prostate gland development, positive regulation of miRNA transcription, tertiary branching involved in mammary gland duct morphogenesis, positive regulation of transcription by RNA polymerase II, single fertilization, positive regulation of transcription by RNA polymerase III, epithelial cell differentiation involved in prostate gland development, regulation of developmental growth, positive regulation of insulin-like growth factor receptor signaling pathway, negative regulation of transcription by RNA polymerase II, cellular response to testosterone stimulus, MAPK cascade, epithelial cell proliferation, mammary gland alveolus development, in utero embryonic development, seminiferous tubule development, male somatic sex determination, androgen receptor signaling pathway, estrogen receptor signaling pathway, membraneless organelle assembly, positive regulation of phosphorylation, regulation of protein localization to plasma membrane, male genitalia morphogenesis, spermatogenesis, morphogenesis of an epithelial fold, epithelial cell morphogenesis, insulin-like growth factor receptor signaling pathway, positive regulation of cell differentiation, animal organ formation, prostate gland growth, positive regulation of MAPK cascade, lateral sprouting involved in mammary gland duct morphogenesis, cellular response to estrogen stimulus, nuclear receptor-mediated steroid hormone signaling pathway, positive regulation of gene expression, negative regulation of epithelial cell proliferation, positive regulation of intracellular estrogen receptor signaling pathway, negative regulation of extrinsic apoptotic signaling pathway, Leydig cell differentiation
GO CC Complete: nucleus, nuclear speck, cytosol, protein-containing complex, chromatin, plasma membrane
Reactome Pathways: Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RHO GTPases activate PKNs, Signal Transduction, RUNX2 regulates osteoblast differentiation, Signaling by Rho GTPases, Ub-specific processing proteases, SUMOylation, Metabolism of proteins, RUNX2 regulates bone development, Post-translational protein modification, Gene expression (Transcription), Cellular responses to stress, Nuclear Receptor transcription pathway, Generic Transcription Pathway, Deubiquitination, RHO GTPase Effectors, Transcriptional regulation by RUNX2, SUMO E3 ligases SUMOylate target proteins, SUMOylation of intracellular receptors, Cellular responses to stimuli, HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand, RNA Polymerase II Transcription