PANTHER Gene Information

Gene Symbol(s):

AMBRA1

Organism:

Sus scrofa

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Gene Name:

Activating molecule in BECN1-regulated autophagy protein 1 isoform X1

Gene ID:

ENSSSCG00000013262.6

Protein ID:

F1SI99

Persistent Id:

PTN001484716

Alternate Ids:

DQIR01095918(EMBL)	ENSSSCG00000013262(Ensembl)
F1SI99(Synonym)	HDA51394(EMBL-CDS)
ENSSSCP00000014094(Ensembl_PRO)	ENSSSCT00000014486(Ensembl_TRS)
XM_005660953(refSeq)	F1SI99_PIG(UniProtKB-ID)
545807777(GI)
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PANTHER Classification

PANTHER Family:	ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 (PTHR22874)
PANTHER Subfamily:	ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 (PTHR22874:SF1)
PANTHER GO-slim Molecular Function:	ubiquitin ligase-substrate adaptor activity
PANTHER GO-slim Biological Process:	autophagosome assembly mitophagy
PANTHER GO-slim Cellular Component:	intracellular membrane-bounded organelle Cul4-RING E3 ubiquitin ligase complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein phosphatase binding, ubiquitin protein ligase binding, protein phosphatase activator activity, GTPase binding, ubiquitin-like ligase-substrate adaptor activity
GO BP Complete:	neural tube development, positive regulation of free ubiquitin chain polymerization, protein polyubiquitination, negative regulation of cell population proliferation, mitophagy, response to mitochondrial depolarisation, regulation of transcription by RNA polymerase II, negative regulation of neuron apoptotic process, positive regulation of mitophagy, autophagosome assembly, positive regulation of regulatory T cell differentiation, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of G1/S transition of mitotic cell cycle, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO CC Complete:	nucleus, intracellular membrane-bounded organelle, mitochondrion, phagocytic vesicle, cytosol, axoneme, Cul4-RING E3 ubiquitin ligase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Autophagy, Macroautophagy

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25990\|UniProtKB=Q9C0C7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003546.6\|UniProtKB=A0A2I3TB21	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011880.3\|UniProtKB=G3S289	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011526.4\|UniProtKB=F7C0N1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2443564\|UniProtKB=A2AH22	Mus musculus	LDO
RAT\|RGD=621330\|UniProtKB=F1LNQ2	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004282.7\|UniProtKB=F1MPW0	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000023789.4\|UniProtKB=A0A3Q2HHC0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013635.6\|UniProtKB=M3WJ74	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027652.1\|UniProtKB=A0A8I3S6E7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019891.5\|UniProtKB=A0A5F8GL02	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014521.4\|UniProtKB=A0A6I8MYJ4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023866.1\|UniProtKB=A0A8V1A264	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004085.4\|UniProtKB=G1KCI2	Anolis carolinensis	LDO
XENLA\|Gene=ambra1.S\|UniProtKB=A0A1L8GDL3	Xenopus laevis	O
XENLA\|Gene=LOC121402910\|UniProtKB=A0A8J1MXI9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-984578\|UniProtKB=F6YH53	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014123.2\|UniProtKB=H2MGH2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-111104-2\|UniProtKB=E7FAG6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050208-235\|UniProtKB=X1WHY6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005523.1\|UniProtKB=W5ME60	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006168.3\|UniProtKB=F7BL69	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414217\|UniProtKB=A0A9J7L1P4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592522\|UniProtKB=A0A7M7P3N7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918760\|UniProtKB=A0A7M7P5A9	Strongylocentrotus purpuratus	LDO
ANOGA\|EnsemblGenome=AGAP009862\|UniProtKB=A0A1S4H368	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC033221\|UniProtKB=A0A139WHE5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_313380\|UniProtKB=E9G440	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011831\|UniProtKB=B7Q8I9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g223189\|UniProtKB=A7T6Y6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g167407\|UniProtKB=A7S7J1	Nematostella vectensis	LDO
CHLRE\|EnsemblGenome=CHLRE_16g655400v5\|UniProtKB=A0A2K3CT49	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00025p00063780\|UniProtKB=W1PW41	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_215G00040\|UniProtKB=A0A0K9PMA8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g04720\|UniProtKB=A0A804HQA8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029634mg\|UniProtKB=K3ZSQ4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G159200\|UniProtKB=A0A1B6QBM3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb097650\|UniProtKB=A0A1D6ENN9	Zea mays	O
SETIT\|EnsemblGenome=SETIT_000312mg\|UniProtKB=K3XEJ5	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G041600\|UniProtKB=A0A1B6PK25	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb087120\|UniProtKB=A0A804MI47	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb420250\|UniProtKB=K7TNH0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0296900\|UniProtKB=Q0J2U9	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os02g0290300\|UniProtKB=Q6K884	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g59200v3\|UniProtKB=I1IF85	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0535330\|UniProtKB=M0XV82	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G539500\|UniProtKB=A0A3B6LWT1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G326800\|UniProtKB=A0A3B6HYP8	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G548800\|UniProtKB=A0A3B6N397	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_013257\|UniProtKB=A0A1U8B2G4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110777756\|UniProtKB=A0A9R0HVY5	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr01g0022411\|UniProtKB=A0A9K3JWR6	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr01g0014861\|UniProtKB=A0A251VND6	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500294710\|UniProtKB=A0A9R1VIV8	Lactuca sativa	O
HELAN\|Gene_ORFName=HannXRQ_Chr10g0280251\|UniProtKB=A0A251TFC4	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr10g0421751\|UniProtKB=A0A9K3HUZ0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900459710\|UniProtKB=A0A9R1UDJ5	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a022633mg\|UniProtKB=A0A022RTD5	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc05g053130.3\|UniProtKB=A0A3Q7GN30	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107828304\|UniProtKB=A0A1S4DCK3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107782769\|UniProtKB=A0A1S3Z476	Nicotiana tabacum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG401001493\|UniProtKB=M0ZMA3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc09g091020.3\|UniProtKB=A0A3Q7J3P1	Solanum lycopersicum	O
TOBAC\|Gene=LOC107776350\|UniProtKB=A0A1S3YHM1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107822349\|UniProtKB=A0A1S4CTC4	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi07g00710\|UniProtKB=F6HZS8	Vitis vinifera	O
BRANA\|Gene_ORFName=GSBRNA2T00063103001\|UniProtKB=A0A078HGJ5	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A09P20690.1\|UniProtKB=A0A078FFI1	Brassica napus	O
BRACM\|EnsemblGenome=Bra027514\|UniProtKB=M4EFF2	Brassica campestris	O
ARATH\|TAIR=locus=2172442\|UniProtKB=F4K7D1	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00031877001\|UniProtKB=A0A078FAP3	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00052516001\|UniProtKB=A0A078H559	Brassica napus	O
BRACM\|EnsemblGenome=Bra032528\|UniProtKB=M4EUP6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00089657001\|UniProtKB=A0A078FRK8	Brassica napus	O
BRACM\|EnsemblGenome=Bra030555\|UniProtKB=M4EP35	Brassica campestris	O
ARATH\|TAIR=locus=2020285\|UniProtKB=F4I458	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107952744\|UniProtKB=A0A1U8NX08	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_003819\|UniProtKB=A0A061DNK2	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g036953mg\|UniProtKB=A0A067EYW4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_014G193900v3\|UniProtKB=A0A2K1XYB7	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_002G254700v3\|UniProtKB=A0A2K2BPH6	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_13G038200\|UniProtKB=A0A2C9UPR2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0996070\|UniProtKB=B9T5V8	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_03G169000\|UniProtKB=I1JPA3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G170300\|UniProtKB=I1N9X3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g069355\|UniProtKB=A0A072VKB4	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_7g099210\|UniProtKB=G7KYK1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_33250\|UniProtKB=A0A2I4H1D1	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_8G212400\|UniProtKB=A0A251N3C7	Prunus persica	O
VITVI\|EnsemblGenome=Vitvi05g00878\|UniProtKB=D7TZ55	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H02881\|UniProtKB=A0A059B2M6	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_D01020\|UniProtKB=A0A059CDV0	Eucalyptus grandis	LDO
GOSHI\|Gene=LOC107929113\|UniProtKB=A0A1U8LN38	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107943110\|UniProtKB=A0A1U8N3C6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_021053\|UniProtKB=A0A061EN46	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004203mg\|UniProtKB=A0A067EXT7	Citrus sinensis	LDO
MANES\|EnsemblGenome=MANES_03G156000\|UniProtKB=A0A2C9W7R8	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_15G047600\|UniProtKB=A0A251JIY2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1023990\|UniProtKB=B9RWS8	Ricinus communis	LDO
JUGRE\|Gene=LOC108980521\|UniProtKB=A0A6P9DUR9	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G169190\|UniProtKB=A0A0A0LKI5	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G053600\|UniProtKB=A0A251QT25	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_413471\|UniProtKB=D8RPK3	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_445918\|UniProtKB=D8SMA7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c10_9370\|UniProtKB=A0A2K1JYD0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c14_5930\|UniProtKB=A0A2K1JGJ8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0068s0020\|UniProtKB=A0A2R6WPM1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_009640030\|UniProtKB=A0A1Y1IVI7	Klebsormidium nitens	LDO