PANTHER Gene Information

Gene Symbol(s):

SCNN1B

Organism:

Sus scrofa

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Tree

Gene Name:

Amiloride-sensitive sodium channel subunit beta

Gene ID:

ENSSSCG00000028923.3

Protein ID:

I3LGX7

Persistent Id:

PTN001363556

Alternate Ids:

HDA25896(EMBL-CDS)	XM_005656773(refSeq)
ENSSSCP00000023321(Ensembl_PRO)	100627971(GeneID)
I3LGX7(Synonym)	ENSSSCT00000029056(Ensembl_TRS)
927183697(GI)	I3LGX7_PIG(UniProtKB-ID)
DQIR01144439(EMBL)	ENSSSCG00000028923(Ensembl)
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PANTHER Classification

PANTHER Family:	AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED (PTHR11690)
PANTHER Subfamily:	AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT BETA (PTHR11690:SF18)
PANTHER GO-slim Molecular Function:	sodium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	sodium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ligand-gated sodium channel activity, WW domain binding
GO BP Complete:	response to food, multicellular organism growth, cellular response to aldosterone, sensory perception of taste, erythrocyte homeostasis, potassium ion homeostasis, aldosterone metabolic process, neutrophil activation involved in immune response, intracellular sodium ion homeostasis, epithelial fluid transport, response to xenobiotic stimulus, renal system process, leukocyte activation involved in inflammatory response, mucus secretion, multicellular organismal-level water homeostasis, cellular response to acidic pH, gene expression, artery smooth muscle contraction, sodium ion transmembrane transport, neutrophil-mediated killing of bacterium, sodium ion import across plasma membrane
GO CC Complete:	sodium channel complex, cytoplasmic vesicle membrane, extracellular exosome, external side of plasma membrane, plasma membrane, apical plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Sensory perception of salty taste, Sensory perception of taste, Stimuli-sensing channels, Ion channel transport, Transport of small molecules, Sensory Perception

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10600\|UniProtKB=P51168	Homo sapiens	LDO
PANTR\|Gene=SCNN1B\|UniProtKB=H2QAR6	Pan troglodytes	LDO
PANTR\|Ensembl=ENSPTRG00000007884.4\|UniProtKB=A0A2I3SU17	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001543.3\|UniProtKB=G3RMU9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000524.4\|UniProtKB=F7A3T9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104696\|UniProtKB=Q9WU38	Mus musculus	LDO
RAT\|RGD=3640\|UniProtKB=P37090	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012290\|UniProtKB=A5D7U4	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000014993.4\|UniProtKB=A0A3Q2H7F7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005173.6\|UniProtKB=M3W3L7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845001896.1\|UniProtKB=A0A8I3N0E7	Canis lupus familiaris	LDO
CANLF\|Ensembl=ENSCAFG00000017687\|UniProtKB=Q95165	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006819.3\|UniProtKB=F6PGF0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014301.3\|UniProtKB=A0A6I8N545	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017490.1\|UniProtKB=A0A8V0Z1H1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000508.4\|UniProtKB=H9G438	Anolis carolinensis	LDO
XENLA\|Gene=scnn1b-b\|UniProtKB=O13262	Xenopus laevis	O
XENLA\|Gene=scnn1b-a\|UniProtKB=P51169	Xenopus laevis	O
XENLA\|Gene=scnn1b.L\|UniProtKB=Q6DE38	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-949109\|UniProtKB=Q0V998	Xenopus tropicalis	LDO
BRAFL\|Gene=LOC118428532\|UniProtKB=A0A9J7N9P2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409427\|UniProtKB=A0A9J7HVH7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409702\|UniProtKB=A0A9J7KMS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429346\|UniProtKB=A0A9J7NAG0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892792\|UniProtKB=A0A7M7N8Z6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891497\|UniProtKB=A0A7M7SUT4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580984\|UniProtKB=A0A7M7HLK0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441174\|UniProtKB=A0A7M7HF55	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100894064\|UniProtKB=A0A7M7SUH3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891818\|UniProtKB=A0A7M7NFP2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891272\|UniProtKB=A0A7M7SV08	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594671\|UniProtKB=A0A7M7PLZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893645\|UniProtKB=A0A7M7LW68	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889460\|UniProtKB=A0A7M7HQL8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889526\|UniProtKB=A0A7M7HK48	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590960\|UniProtKB=A0A7M7N8K7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105436466\|UniProtKB=A0A7M7N8V4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890654\|UniProtKB=A0A7M7N7N9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446529\|UniProtKB=A0A7M7SUJ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891438\|UniProtKB=A0A7M7N919	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763355\|UniProtKB=A0A7M7GA14	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00012116\|UniProtKB=P91835	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00319\|UniProtKB=A8WMP7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112486\|UniProtKB=A0A2A6CCV0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277773\|UniProtKB=A0A2A6CCE7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00012137\|UniProtKB=Q22851	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11871\|UniProtKB=A8XE73	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280100\|UniProtKB=A0A2A6CNI2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095582\|UniProtKB=A0A2A6C4I7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116949\|UniProtKB=A0A2A6CKV1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279138\|UniProtKB=A0A2A6C436	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096276\|UniProtKB=A0A2A6BKI1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101632\|UniProtKB=A0A2A6BNT5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00104647\|UniProtKB=A0A2A6B9T3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00118917\|UniProtKB=A0A2A6CKT1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101834\|UniProtKB=A0A2A6CMD1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095667\|UniProtKB=A0A2A6C296	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117455\|UniProtKB=A0A2A6CGP7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272665\|UniProtKB=A0A2A6CL11	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101230\|UniProtKB=A0A2A6BXY3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00000950\|UniProtKB=P24585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16785\|UniProtKB=A8XPT2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00093227\|UniProtKB=A0A2A6CPP4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00093226\|UniProtKB=A0A2A6B2S3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279530\|UniProtKB=A0A2A6CM49	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00275338\|UniProtKB=A0A2A6BFR6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006748\|UniProtKB=Q21974	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05805\|UniProtKB=A8X1K9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00006832\|UniProtKB=Q09274	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00750\|UniProtKB=A8WN53	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099877\|UniProtKB=A0A2A6B6V6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015957\|UniProtKB=Q18077	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034808\|UniProtKB=A8XJL2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095216\|UniProtKB=A0A2A6CTU1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018906\|UniProtKB=Q20852	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013486\|UniProtKB=Q9U1T9	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013480\|UniProtKB=Q9XTS9	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013487\|UniProtKB=Q9U1T8	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00278527\|UniProtKB=A0A2A6C4X9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117929\|UniProtKB=A0A2A6CKC6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00282848\|UniProtKB=A0A2A6BSU9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096858\|UniProtKB=A0A2A6C5A6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101875\|UniProtKB=A0A2A6CSQ8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272170\|UniProtKB=A0A2A6BSL6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096852\|UniProtKB=A0A2A6C5E4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095605\|UniProtKB=A0A2A6C3N7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00000952\|UniProtKB=Q19038	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG07259\|UniProtKB=A8X543	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00089711\|UniProtKB=A0A2A6BEQ4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003174\|UniProtKB=P34886	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041260\|UniProtKB=Q60NC0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272421\|UniProtKB=A0A2A6BBZ6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003168\|UniProtKB=P24612	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036254\|UniProtKB=Q17298	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275832\|UniProtKB=A0A8R1YZS0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091439\|UniProtKB=A0A2A6C9S0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00010334\|UniProtKB=G5EFH3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17520\|UniProtKB=A8XRD5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00022815\|UniProtKB=O01635	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11997\|UniProtKB=A8XEB1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278793\|UniProtKB=A0A2A6C4B2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117196\|UniProtKB=A0A2A6BU03	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272164\|UniProtKB=A0A2A6BSZ7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00098838\|UniProtKB=A0A2A6CCT1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032602\|UniProtKB=Q9VJI4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010146\|UniProtKB=Q7Q0V0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC005481\|UniProtKB=D6WY25	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW017829\|UniProtKB=B7PEV5	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW028495\|UniProtKB=A0A905FYF3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002325\|UniProtKB=A0A1S4KQ07	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023720\|UniProtKB=B7QI61	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213150\|UniProtKB=A7SJB5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218891\|UniProtKB=A7SX71	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136400\|UniProtKB=A7SX80	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211338\|UniProtKB=A7SF69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215544\|UniProtKB=A7SPS2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215206\|UniProtKB=A7SP23	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211570\|UniProtKB=A7SFR0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205746\|UniProtKB=A7S2F2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211334\|UniProtKB=A7SF65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211571\|UniProtKB=A7SFR1	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54579\|UniProtKB=B3RSF6	Trichoplax adhaerens	O