PANTHER Gene Information   
Gene Symbol(s): TRADD
Organism: Sus scrofa
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Gene Name: Tumor necrosis factor receptor type 1-associated DEATH domain protein
Gene ID: ENSSSCG00005009895.1
Protein ID: A0A287BPE4
Persistent Id: PTN001429498
Alternate Ids:
XM_013992385(refSeq) HDB98251(EMBL-CDS)
ENSSSCP00000057975(Ensembl_PRO) A0A287BPE4_PIG(UniProtKB-ID)
DQIR01242774(EMBL) ENSSSCT00000046588(Ensembl_TRS)
927226423(GI) ENSSSCG00005009895(Ensembl)
A0A287BPE4(Synonym)
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PANTHER Classification
PANTHER Family: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN (PTHR14913)
PANTHER Subfamily: TUMOR NECROSIS FACTOR RECEPTOR TYPE 1-ASSOCIATED DEATH DOMAIN PROTEIN (PTHR14913:SF0)  
PANTHER GO-slim Molecular Function: receptor tyrosine kinase binding
signaling receptor complex adaptor activity
PANTHER GO-slim Biological Process: extrinsic apoptotic signaling pathway
PANTHER GO-slim Cellular Component: receptor complex
PANTHER protein class:
Pathway Categories: Apoptosis signaling pathway
   TNFR1 associated death domain

GO MF Complete: identical protein binding, transmembrane receptor protein tyrosine kinase adaptor activity, death domain binding
GO BP Complete: tumor necrosis factor-mediated signaling pathway, TRAIL-activated apoptotic signaling pathway, positive regulation of inflammatory response, positive regulation of canonical NF-kappaB signal transduction, extrinsic apoptotic signaling pathway, cell surface receptor protein tyrosine kinase signaling pathway, canonical NF-kappaB signal transduction, positive regulation of hair follicle development, positive regulation of cell migration
GO CC Complete: nucleus, cytoskeleton, cytoplasm, tumor necrosis factor receptor superfamily complex, plasma membrane
Reactome Pathways: Regulation of TNFR1 signaling, Apoptosis, RIPK1-mediated regulated necrosis, Signal Transduction, TNF signaling, Dimerization of procaspase-8, TNFR1-induced proapoptotic signaling, TNFR1-induced NF-kappa-B signaling pathway, Caspase activation via extrinsic apoptotic signalling pathway, Programmed Cell Death, Death Receptor Signaling, Caspase activation via Death Receptors in the presence of ligand, Regulated Necrosis, Regulation by c-FLIP, Regulation of necroptotic cell death, CASP8 activity is inhibited