PANTHER Gene Information

Gene Symbol(s):

Ube4a

Organism:

Rattus norvegicus

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Gene Name:

Ubiquitin conjugation factor E4 A

Gene ID:

1303173

Protein ID:

Q6P7A2

Persistent Id:

PTN000358182

Alternate Ids:

UBE4A_RAT(UniProtKB-ID)	AAH61761(EMBL-CDS)
Ube4a{ECO:0000312\|RGD:1303173}(Symbol)	NM_207610(refSeq)
315608(GeneID)	1303173(RGD)
2.3.2.27 {ECO:0000250\|UniProtKB:E9Q735}(EC)	RING-type E3 ubiquitin transferase E4 A(Synonym)
BC061761(EMBL)	38197420(GI)
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PANTHER Classification

PANTHER Family:	UBIQUITINATION FACTOR E4 (PTHR13931)
PANTHER Subfamily:	UBIQUITIN CONJUGATION FACTOR E4 A (PTHR13931:SF16)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	protein polyubiquitination ERAD pathway
PANTHER GO-slim Cellular Component:	nucleus cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin protein ligase activity, ubiquitin-ubiquitin ligase activity
GO BP Complete:	protein polyubiquitination, ubiquitin-dependent protein catabolic process, ERAD pathway
GO CC Complete:	nucleus, ubiquitin ligase complex, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Class I MHC mediated antigen processing & presentation, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Adaptive Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=12499\|UniProtKB=Q14139	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004341.5\|UniProtKB=K6ZZ85	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000011416.3\|UniProtKB=A0A2I2ZD19	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000045160.2\|UniProtKB=H9G1Y1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2154580\|UniProtKB=E9Q735	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000019725\|UniProtKB=A5PKG6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015095.5\|UniProtKB=A0A5G2QH63	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011764.4\|UniProtKB=A0A9L0RZB3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011778.6\|UniProtKB=M3WFR4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845002347.1\|UniProtKB=A0A8I3RS55	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000013491.4\|UniProtKB=F7F8S8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005343.3\|UniProtKB=F6X8P8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024283.1\|UniProtKB=A0A8V0ZZ44	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007112.4\|UniProtKB=H9GCF3	Anolis carolinensis	LDO
XENLA\|Gene=ube4a.S\|UniProtKB=Q4FZX1	Xenopus laevis	O
XENLA\|Gene=ube4a.L\|UniProtKB=A0A1L8FLJ3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-922256\|UniProtKB=F6VBF6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007707.2\|UniProtKB=H2LU81	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070410-21\|UniProtKB=E7F6E1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003975.1\|UniProtKB=W5M8S9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006881.3\|UniProtKB=F6YV51	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC581667\|UniProtKB=A0A7M7SV09	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0028467\|UniProtKB=Q9U4F8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001681\|UniProtKB=Q7PUV9	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002590\|UniProtKB=D6WFJ1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_56866\|UniProtKB=E9H124	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW012014\|UniProtKB=B7QAW7	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g240861\|UniProtKB=A7RUX2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG60429\|UniProtKB=B3S870	Trichoplax adhaerens	LDO
YEAST\|SGD=S000002349\|UniProtKB=P54860	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR096C\|UniProtKB=Q75A24	Eremothecium gossypii	O
CANAL\|CGD=CAL0000195094\|UniProtKB=Q5AND8	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D12452g\|UniProtKB=Q6C9B7	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10556\|UniProtKB=C8V8J9	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G07340\|UniProtKB=Q4WNY0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03357\|UniProtKB=V5IN07	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_03940\|UniProtKB=A7EF49	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_04835\|UniProtKB=Q0UTS9	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC20H4.10\|UniProtKB=Q9HE05	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02685\|UniProtKB=B6K0W7	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNL04300\|UniProtKB=Q5K8W1	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04327\|UniProtKB=A0A0D1BZS3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_11097\|UniProtKB=E3KND2	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11100\|UniProtKB=E3KND5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_34827\|UniProtKB=F4NZS7	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_138180\|UniProtKB=C4M3H2	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0292264\|UniProtKB=O44007	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_59083\|UniProtKB=F1A496	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_1010\|UniProtKB=Q4Q7K2	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.6.2460\|UniProtKB=Q584R0	Trypanosoma brucei	O
TRIV3\|Gene_ORFName=TVAG_126330\|UniProtKB=A2ED21	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0826500\|UniProtKB=C0H4Y0	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00018248001\|UniProtKB=A0DLL3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031221001\|UniProtKB=A0BR25	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028431001\|UniProtKB=A0BFS9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016901001\|UniProtKB=A0DHJ7	Paramecium tetraurelia	O
PHYRM\|Gene=H3HCX8_PHYRM\|UniProtKB=H3HCX8	Phytophthora ramorum	O
PHYRM\|Gene=H3HD31_PHYRM\|UniProtKB=H3HD31	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_12g510300v5\|UniProtKB=A0A2K3D2N2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g398350v5\|UniProtKB=A0A2K3DD15	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00177p00048180\|UniProtKB=W1PSR9	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_287G00040\|UniProtKB=A0A0K9PCZ8	Zostera marina	O
MUSAM\|EnsemblGenome=Ma10_g11900\|UniProtKB=A0A804KV87	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_034048mg\|UniProtKB=K4A594	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G333100\|UniProtKB=C5WWH4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb020370\|UniProtKB=A0A1D6K5Z1	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb393280\|UniProtKB=K7WCZ1	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0427900\|UniProtKB=Q75I67	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g16140v3\|UniProtKB=I1GQS1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0737910\|UniProtKB=A0A8I6YGT2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7D02G464800\|UniProtKB=A0A3B6TXN5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G477300\|UniProtKB=A0A3B6RQT0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G378900\|UniProtKB=A0A3B6SJ14	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_010238\|UniProtKB=A0A1U8A897	Nelumbo nucifera	O
SPIOL\|Gene=LOC110799797\|UniProtKB=A0A9R0K7Y4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0711061\|UniProtKB=A0A251SBK3	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr09g0400911\|UniProtKB=A0A9K3I8I5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400222180\|UniProtKB=A0A9R1VUL1	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000649mg\|UniProtKB=A0A022RYW6	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_07032\|UniProtKB=A0A1U8G055	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400007132\|UniProtKB=M1AAI0	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g074770.3\|UniProtKB=A0A3Q7H302	Solanum lycopersicum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400001440\|UniProtKB=M0ZM28	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc02g088550.3\|UniProtKB=A0A3Q7FAR2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107827966\|UniProtKB=A0A1S4DB64	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777862\|UniProtKB=A0A1S3YMJ6	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g02016\|UniProtKB=D7SXH7	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I01989\|UniProtKB=A0A059ARB1	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00035211001\|UniProtKB=A0A078GM66	Brassica napus	O
BRACM\|EnsemblGenome=Bra023516\|UniProtKB=M4E413	Brassica campestris	O
BRACM\|EnsemblGenome=Bra008700\|UniProtKB=M4CWV3	Brassica campestris	O
ARATH\|TAIR=locus=2180862\|UniProtKB=Q9LF41	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107888562\|UniProtKB=A0A1U8HXV3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_018688\|UniProtKB=A0A061EGQ1	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g001583mg\|UniProtKB=A0A067FZE7	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_004G121200v3\|UniProtKB=A0A2K2ATG5	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G122400v3\|UniProtKB=A0A2K2ATI5	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_017G089600v3\|UniProtKB=B9IK34	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G099400\|UniProtKB=A0A2C9WJG6	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0169100\|UniProtKB=B9T3S8	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_19G027200\|UniProtKB=A0A368UGC3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G059200\|UniProtKB=I1LWP5	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g013690\|UniProtKB=G7KLS4	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr01_10770\|UniProtKB=A0A2I4E8W8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G824780\|UniProtKB=A0A0A0LCQ5	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G259400\|UniProtKB=M5X3L3	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_142432\|UniProtKB=D8QZQ6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_162102\|UniProtKB=D8T8W5	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c15_20630\|UniProtKB=A0A2K1JDW3	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0052s0078\|UniProtKB=A0A2R6WWR1	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003310040\|UniProtKB=A0A1Y1IAV4	Klebsormidium nitens	O