PANTHER Gene Information

Gene Symbol(s):

Desi1

Organism:

Rattus norvegicus

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Gene Name:

Desumoylating isopeptidase 1

Gene ID:

1305776

Protein ID:

Q4KM30

Persistent Id:

PTN000272341

Alternate Ids:

3.4.-.-(EC)	DeSI-1(Synonym)
Desi1(Symbol)	NP_001020874(refSeq)
AAH98857(EMBL-CDS)	123782093(GI)
315160(GeneID)	1305776(RGD)
DESI1_RAT(UniProtKB-ID)	BC098857(EMBL)
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PANTHER Classification

PANTHER Family:	DESUMOYLATING ISOPEPTIDASE (PTHR12378)
PANTHER Subfamily:	DESUMOYLATING ISOPEPTIDASE 1 (PTHR12378:SF7)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	protein modification by small protein removal
PANTHER GO-slim Cellular Component:
PANTHER protein class:	cysteine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	identical protein binding, palmitoyl-(protein) hydrolase activity, long-chain fatty acyl-CoA hydrolase activity, deSUMOylase activity, peptidase activity, importin-alpha family protein binding
GO BP Complete:	macromolecule depalmitoylation, protein desumoylation, proteolysis, protein export from nucleus, regulation of proteasomal ubiquitin-dependent protein catabolic process, protein modification by small protein removal
GO CC Complete:	nucleus, cytosol, protein-containing complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24577\|UniProtKB=Q6ICB0	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014433.4\|UniProtKB=A0A2I3SBP1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015877.3\|UniProtKB=A0A2I2Z916	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000050219.1\|UniProtKB=G7N3Z4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=106313\|UniProtKB=Q9CQT7	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000047942.2\|UniProtKB=G3N176	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000034265.3\|UniProtKB=A0A480K058	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011960.4\|UniProtKB=F6VE96	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000033281.3\|UniProtKB=A0A2I2UWM2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016514.1\|UniProtKB=A0A8I3NV77	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016577.3\|UniProtKB=H9H700	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000044638.1\|UniProtKB=A0A6I8NR53	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010831.1\|UniProtKB=A0A8V0Y1Y5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004597.3\|UniProtKB=G1KCY7	Anolis carolinensis	LDO
XENLA\|Gene=desi1\|UniProtKB=Q6GLM5	Xenopus laevis	O
XENLA\|Gene=desi1.S\|UniProtKB=A0A1L8GGR6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-998981\|UniProtKB=A0A803JE79	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013243.2\|UniProtKB=H2MDF1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-936\|UniProtKB=Q7ZTH7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1657\|UniProtKB=Q6PC81	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011526.1\|UniProtKB=W5N0K1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014597.2\|UniProtKB=F6SYB9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428911\|UniProtKB=A0A9J7M5K4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105445099\|UniProtKB=A0A7M7T591	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC593529\|UniProtKB=A0A7M7SYG4	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC005716\|UniProtKB=D6WWN5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033356\|UniProtKB=A0A139WGN5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC006219\|UniProtKB=A0A139WDU8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_198868\|UniProtKB=E9GVF2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004844\|UniProtKB=B7PE88	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG64188\|UniProtKB=T1FXR1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83774\|UniProtKB=A7RJX2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG17307\|UniProtKB=B3RPZ4	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000200680\|UniProtKB=Q5AJX5	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F09812g\|UniProtKB=Q6C289	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06915\|UniProtKB=Q5AXR5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G13640\|UniProtKB=Q4WVX4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03714\|UniProtKB=Q1K7Y6	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00115\|UniProtKB=A7E493	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_16047\|UniProtKB=Q0TWX3	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNK01620\|UniProtKB=Q5K9K8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04578\|UniProtKB=A0A0D1DY72	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04168\|UniProtKB=E3K1N7	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0292886\|UniProtKB=Q54CK2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_149119\|UniProtKB=F0ZCW5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_1330\|UniProtKB=Q4Q5E9	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6150\|UniProtKB=Q381Y2	Trypanosoma brucei	LDO
GIAIC\|Gene_ORFName=GL50803_0024425\|UniProtKB=A0A644F9E9	Giardia intestinalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1217900\|UniProtKB=Q8I5M9	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00026519001\|UniProtKB=A0EFV5	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00024055001\|UniProtKB=A0E7R0	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_38948\|UniProtKB=B8BSV3	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GSB2_PHYRM\|UniProtKB=H3GSB2	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g662450v5\|UniProtKB=A0A2K3CTN3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g555850v5\|UniProtKB=A8IYR6	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00067p00169770\|UniProtKB=U5DER6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_206G00130\|UniProtKB=A0A0K9PLH1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g33060\|UniProtKB=A0A804IWN4	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g12670\|UniProtKB=A0A804J3S2	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3001G222200\|UniProtKB=A0A1B6QKA6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb221910\|UniProtKB=A0A804PB67	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0472400\|UniProtKB=Q337L1	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g28530v3\|UniProtKB=A0A2K2CZT6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0042110\|UniProtKB=F2DBG9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G169200\|UniProtKB=A0A3B5YVS4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G151600\|UniProtKB=A0A3B5XXW8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G148600\|UniProtKB=A0A3B5ZSJ9	Triticum aestivum	LDO
SETIT\|EnsemblGenome=SETIT_018112mg\|UniProtKB=K3YV16	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G341800\|UniProtKB=C5XVT5	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb258670\|UniProtKB=A0A1D6HP63	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0814000\|UniProtKB=Q6K3E0	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g55090v3\|UniProtKB=I1IDT4	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0628660\|UniProtKB=F2E3I1	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6D02G369300\|UniProtKB=A0A3B6QNU3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G384300\|UniProtKB=A0A3B6NWF6	Triticum aestivum	O
NELNU\|Gene=LOC104589375\|UniProtKB=A0A1U7ZET9	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_007655\|UniProtKB=A0A1U8ABD4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110775510\|UniProtKB=A0A9R0HRT4	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0169171\|UniProtKB=A0A251UYE9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0249621\|UniProtKB=A0A251TH06	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800424660\|UniProtKB=A0A9R1US30	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0421111\|UniProtKB=A0A251TF79	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0676971\|UniProtKB=A0A251S754	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500294380\|UniProtKB=A0A9R1V9D8	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C900460280\|UniProtKB=A0A9R1WU34	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a012018mg\|UniProtKB=A0A022S4Q6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_23362\|UniProtKB=A0A2G2YS35	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017659\|UniProtKB=M1BHT4	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g061310.3\|UniProtKB=A0A3Q7I303	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107822016\|UniProtKB=A0A1S4CSE2	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107759334\|UniProtKB=A0A1S3WYK0	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00914\|UniProtKB=F6I015	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K02178\|UniProtKB=A0A059A577	Eucalyptus grandis	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K021731\|UniProtKB=A0A059A432	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00055672001\|UniProtKB=A0A078JJZ0	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00057489001\|UniProtKB=A0A078H8V8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029621\|UniProtKB=M4ELF3	Brassica campestris	O
BRACM\|EnsemblGenome=Bra040360\|UniProtKB=M4FGY2	Brassica campestris	LDO
ARATH\|TAIR=locus=2098560\|UniProtKB=Q9SFT9	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107939000\|UniProtKB=A0A1U8MLT4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924547\|UniProtKB=A0A1U8L7G4	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107912579\|UniProtKB=A0A1U8K5Q9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_002959\|UniProtKB=A0A061DM98	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_002G241700v3\|UniProtKB=B9GNJ9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_13G045400\|UniProtKB=A0A2C9UQ49	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1720950\|UniProtKB=B9S535	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G354700\|UniProtKB=I1KZA2	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_18G170900\|UniProtKB=C6THR3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g058510\|UniProtKB=G7L195	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr10_12880\|UniProtKB=A0A2I4EQI9	Juglans regia	O
JUGRE\|EnsemblGenome=Jr01_17760\|UniProtKB=A0A6P9E770	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G627710\|UniProtKB=A0A0A0L8S4	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_7G339120\|UniProtKB=A0A0A0K6Q6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G203600\|UniProtKB=M5W6T2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_6987\|UniProtKB=D8RZV9	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_99026\|UniProtKB=D8RPY8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_105471\|UniProtKB=D8RZN9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c11_1330\|UniProtKB=A0A2K1JT67	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c14_10250\|UniProtKB=A0A7I4AQD7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0051s0047\|UniProtKB=A0A2R6WX87	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001050090\|UniProtKB=A0A1Y1HUD5	Klebsormidium nitens	LDO