PANTHER Gene Information   
Gene Symbol(s): Cnot8
Organism: Rattus norvegicus
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Gene Name: poly(A)-specific ribonuclease
Gene ID: 1306401
Protein ID: Q5U2U9
Persistent Id: PTN000084104
Alternate Ids:
XP_006246454(refSeq) 564372040(GI)
Q5U2U9_RAT(UniProtKB-ID) 363603(GeneID)
1306401(RGD) ENSRNOG00000002630(Ensembl)
Q5U2U9(Synonym) ENSRNOT00000003555(Ensembl_TRS)
ENSRNOP00000003555(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT (PTHR10797)
PANTHER Subfamily: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 8 (PTHR10797:SF1)  
PANTHER GO-slim Molecular Function: 3'-5'-RNA exonuclease activity
PANTHER GO-slim Biological Process: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
PANTHER GO-slim Cellular Component: CCR4-NOT complex
P-body
PANTHER protein class: mRNA polyadenylation factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: nucleic acid binding, poly(A)-specific ribonuclease activity, 3'-5'-RNA exonuclease activity
GO BP Complete: biological_process, positive regulation of mRNA catabolic process, positive regulation of cell population proliferation, miRNA-mediated gene silencing by mRNA destabilization
GO CC Complete: nucleus, CCR4-NOT complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Generic Transcription Pathway, TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain, TP53 Regulates Transcription of Cell Cycle Genes, Transcriptional Regulation by TP53, Gene expression (Transcription), RNA Polymerase II Transcription

Orthologs