PANTHER Gene Information

Gene Symbol(s):

Septin4

Organism:

Rattus norvegicus

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Gene Name:

Septin-4

Gene ID:

1308781

Protein ID:

A0A096MJN4

Persistent Id:

PTN002315366

Alternate Ids:

AABR07030186(EMBL)	ENSRNOG00000007367(Ensembl)
ENSRNOP00000068198(Ensembl_PRO)	287606(GeneID)
XP_017452610(refSeq)	SEPT4_RAT(UniProtKB-ID)
Arts{ECO:0000250\|UniProtKB:O43236}(Synonym)	1308781(RGD)
2203845938(GI)	Septin4{ECO:0000312\|RGD:1308781}(Symbol)
ENSRNOT00000076026(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	SEPTIN (PTHR18884)
PANTHER Subfamily:	SEPTIN-4 (PTHR18884:SF71)
PANTHER GO-slim Molecular Function:	GTPase activity
PANTHER GO-slim Biological Process:	protein localization regulation of exocytosis cytoskeleton-dependent cytokinesis
PANTHER GO-slim Cellular Component:	cell cortex protein-containing complex microtubule cytoskeleton synaptic vesicle cell division site
PANTHER protein class:	cytoskeletal protein

Pathway Categories:

Parkinson disease

Cell division cycle-related protein 1

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	magnesium ion binding, GTP binding, identical protein binding, GTPase activity, molecular adaptor activity
GO BP Complete:	cytoskeleton-dependent cytokinesis, tissue morphogenesis, spermatid development, spermatogenesis, sperm mitochondrion organization, hematopoietic stem cell homeostasis, protein localization, spermatid differentiation, brain development, cell division, neuron migration, flagellated sperm motility, sperm capacitation, negative regulation of stem cell proliferation, positive regulation of apoptotic process, cell differentiation, positive regulation of protein ubiquitination, regulation of exocytosis, positive regulation of intrinsic apoptotic signaling pathway
GO CC Complete:	microtubule cytoskeleton, cell division site, synaptic vesicle, perikaryon, cell projection, axon terminus, nucleoplasm, septin ring, dopaminergic synapse, dendrite, motile cilium, presynapse, cytoskeleton, cytoplasm, sperm annulus, mitochondrion, transport vesicle, septin complex, sperm flagellum, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Apoptotic factor-mediated response, Apoptosis, Programmed Cell Death, Intrinsic Pathway for Apoptosis, Release of apoptotic factors from the mitochondria, SMAC, XIAP-regulated apoptotic response

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9165\|UniProtKB=O43236	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009455.6\|UniProtKB=A0A2I3SHG8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013814.3\|UniProtKB=G3RD82	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008423.4\|UniProtKB=F6VBY7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1270156\|UniProtKB=P28661	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000015368.6\|UniProtKB=A0A3Q1MXU1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005016917.1\|UniProtKB=F1RRN6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020248.4\|UniProtKB=F6UN58	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004488.6\|UniProtKB=M3W298	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021290.1\|UniProtKB=A0A8I3P8G9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014657.4\|UniProtKB=A0A5F8G6T3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000042891.1\|UniProtKB=A0A6I8PHS4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029585.1\|UniProtKB=A0A8V1AMU0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000041095.1\|UniProtKB=A0A803T323	Anolis carolinensis	LDO
XENLA\|Gene=LOC108707995\|UniProtKB=A0A8J0UCT0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-983580\|UniProtKB=A0A8J0QME6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000002766.2\|UniProtKB=A0A3B3HL60	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007856.2\|UniProtKB=H2LUR2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070424-28\|UniProtKB=A3KNM3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-051120-87\|UniProtKB=Q32LU3	Danio rerio	O
DANRE\|Gene=sept4b\|UniProtKB=A0A8M9QPP7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002731.1\|UniProtKB=W5M4A5	lepisosteus oculatus	O
BRAFL\|Gene=LOC118425521\|UniProtKB=A0A9J7N515	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC587790\|UniProtKB=A0A7M7MYV7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105445967\|UniProtKB=A0A7M7PCG8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00015956\|UniProtKB=H2KYV3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034807\|UniProtKB=A8XJL1	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0259923\|UniProtKB=Q0KHR7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000768\|UniProtKB=A0A1S4G9T6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006627\|UniProtKB=D6WXZ1	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_107198\|UniProtKB=E9GWA3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW018707\|UniProtKB=B7PKQ6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG68096\|UniProtKB=T1FZA2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g239234\|UniProtKB=A7RLX3	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27671\|UniProtKB=A9V5Z3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21013\|UniProtKB=A9UP35	Monosiga brevicollis	O
YEAST\|SGD=S000003291\|UniProtKB=P41901	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR571W\|UniProtKB=Q752K3	Eremothecium gossypii	O
YEAST\|SGD=S000001149\|UniProtKB=P32468	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AER238C\|UniProtKB=Q756L6	Eremothecium gossypii	O
CANAL\|CGD=CAL0000192509\|UniProtKB=A0A1D8PGH0	Candida albicans	O
CANAL\|CGD=CAL0000175669\|UniProtKB=A0A1D8PCY5	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F26873g\|UniProtKB=Q6C088	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D27148g\|UniProtKB=Q6C7L3	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_08182\|UniProtKB=C8V742	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G03080\|UniProtKB=Q4WEI0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03795\|UniProtKB=Q1K7H5	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07713\|UniProtKB=A7EQW0	Sclerotinia sclerotiorum	O
SCHPO\|PomBase=SPCC188.12\|UniProtKB=Q09883	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03688\|UniProtKB=B6K4X4	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC9G1.11c\|UniProtKB=P48009	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03374\|UniProtKB=B6K425	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC02440\|UniProtKB=Q5KKN2	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_03599\|UniProtKB=A0A0D1C4D8	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_15677\|UniProtKB=E3KZ03	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33494\|UniProtKB=F4P7H5	Batrachochytrium dendrobatidis	O
YEAST\|SGD=S000004306\|UniProtKB=P32457	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR111C\|UniProtKB=Q754F9	Eremothecium gossypii	O
CANAL\|CGD=CAL0000192358\|UniProtKB=A0A1D8PD83	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D23595g\|UniProtKB=Q6C816	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06688\|UniProtKB=C8V1M3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G05370\|UniProtKB=Q4WGK7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08297\|UniProtKB=V5IMG4	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_13230\|UniProtKB=A7F6K1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_13464\|UniProtKB=Q0U450	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC4F10.11\|UniProtKB=O36023	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01277\|UniProtKB=B6K085	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNF00500\|UniProtKB=Q5KFU8	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10503\|UniProtKB=A0A0D1DV64	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_21853\|UniProtKB=H6QSR8	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_04248\|UniProtKB=E3K2X2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_36444\|UniProtKB=F4NVA9	Batrachochytrium dendrobatidis	O
PARTE\|EnsemblGenome=GSPATT00037648001\|UniProtKB=Q3SED9	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_06g281600v5\|UniProtKB=A0A2K3DPP2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g556250v5\|UniProtKB=A8IYS5	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_000160380\|UniProtKB=A0A1Y1HJC8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_009280030\|UniProtKB=A0A1Y1ITX3	Klebsormidium nitens	O