PANTHER Gene Information

Gene Symbol(s):

Ing4

Organism:

Rattus norvegicus

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Gene Name:

Inhibitor of growth protein

Gene ID:

1309407

Protein ID:

A0A8J8YN55

Persistent Id:

PTN000036022

Alternate Ids:

1309407(RGD)	A0A8J8YN55_RAT(UniProtKB-ID)
A0A8J8YN55(Synonym)	ENSRNOT00000024116(Ensembl_TRS)
ENSRNOP00000024116(Ensembl_PRO)	ENSRNOG00000023363(Ensembl)
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PANTHER Classification

PANTHER Family:	INHIBITOR OF GROWTH PROTEIN (PTHR10333)
PANTHER Subfamily:	INHIBITOR OF GROWTH PROTEIN 4 (PTHR10333:SF106)
PANTHER GO-slim Molecular Function:	methylated histone binding
PANTHER GO-slim Biological Process:	positive regulation of apoptotic process regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	transcription coactivator activity, metal ion binding, methylated histone binding, histone H4K16 acetyltransferase activity, histone H3K14 acetyltransferase activity, histone H4K8 acetyltransferase activity, histone H4K5 acetyltransferase activity, histone H4K12 acetyltransferase activity
GO BP Complete:	negative regulation of growth, positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, negative regulation of cell population proliferation, regulation of DNA-templated transcription, protein acetylation, chromatin remodeling, regulation of cell cycle G2/M phase transition, negative regulation of DNA-templated transcription, regulation of cell growth, positive regulation of DNA-templated transcription, DNA replication-dependent chromatin disassembly, positive regulation of apoptotic process, regulation of DNA biosynthetic process, regulation of cell cycle
GO CC Complete:	nucleus, intermediate filament cytoskeleton, cytosol, histone acetyltransferase complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

HATs acetylate histones, Chromatin modifying enzymes, Chromatin organization

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19423\|UniProtKB=Q9UNL4	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004583.6\|UniProtKB=H2Q5A9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016035.3\|UniProtKB=G3RIX2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016985.4\|UniProtKB=A0A1D5R9G0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=107307\|UniProtKB=Q8C0D7	Mus musculus	LDO
BOVIN\|Gene=ING4\|UniProtKB=Q3T095	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000017064.4\|UniProtKB=F1MD09	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000044078.2\|UniProtKB=F1SL45	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024784.4\|UniProtKB=A0A5F5Q1H6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006880.6\|UniProtKB=A0A2I2U6Q5	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000018103.4\|UniProtKB=A0A5F8H269	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000036657.1\|UniProtKB=A0A6I8NLX7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021674.1\|UniProtKB=A0A8V0ZLF3	Gallus gallus	O
CHICK\|Gene_ORFName=RCJMB04_8l5\|UniProtKB=Q5ZKY4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006150.4\|UniProtKB=H9GB24	Anolis carolinensis	LDO
XENLA\|Gene=ing4.S\|UniProtKB=A0A8J1LBB7	Xenopus laevis	O
XENLA\|Gene=ing4.L\|UniProtKB=A0A8J0TA97	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1013994\|UniProtKB=A0A6I8R8V9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012172.2\|UniProtKB=H2M9N9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050522-47\|UniProtKB=Q4VBS0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007026.1\|UniProtKB=W5MJF7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006273.3\|UniProtKB=F6V2A4	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_114530\|UniProtKB=C3ZSF3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115921070\|UniProtKB=A0A7M7NB58	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892388\|UniProtKB=A0A7M7HNP5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC589170\|UniProtKB=A0A7M7NWI7	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00110930\|UniProtKB=A0A2A6B9U8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032516\|UniProtKB=Q9VJY8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009992\|UniProtKB=Q7Q136	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC031978\|UniProtKB=A0A139WP05	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013703\|UniProtKB=D6WK90	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308315\|UniProtKB=E9H799	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG185182\|UniProtKB=T1FMH3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG184897\|UniProtKB=T1FM50	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230105\|UniProtKB=A7SFP0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50425\|UniProtKB=B3S007	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25212\|UniProtKB=A9UYR1	Monosiga brevicollis	LDO
YEAST\|SGD=S000001132\|UniProtKB=P38806	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AEL100W\|UniProtKB=Q757W2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000174600\|UniProtKB=Q5AHB8	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E14773g\|UniProtKB=Q6C5V7	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_09126\|UniProtKB=Q5ARF4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G01870\|UniProtKB=Q4WAM9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02796\|UniProtKB=V5IQP9	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04237\|UniProtKB=A7EFZ6	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00461\|UniProtKB=Q0V6A3	Phaeosphaeria nodorum	O
YEAST\|SGD=S000005041\|UniProtKB=P50947	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL263W\|UniProtKB=Q75B40	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000188113\|UniProtKB=A0A1D8PIP3	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E08822g\|UniProtKB=Q6C6K6	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05570\|UniProtKB=Q5B1L0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G11660\|UniProtKB=Q4WQ59	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03461\|UniProtKB=Q7RWJ4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_06103\|UniProtKB=A7ELA6	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06442\|UniProtKB=Q0UP72	Phaeosphaeria nodorum	LDO
CANAL\|CGD=CAL0000191789\|UniProtKB=A0A1D8PIA8	Candida albicans	O
EMENI\|EnsemblGenome=ANIA_02857\|UniProtKB=Q5B9C3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G11940\|UniProtKB=Q4WY63	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00070\|UniProtKB=Q7RX80	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07346\|UniProtKB=A7EPU7	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05780\|UniProtKB=Q0UR34	Phaeosphaeria nodorum	O
PHANO\|Gene_ORFName=SNOG_02383\|UniProtKB=Q0V0T1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC3G9.08\|UniProtKB=O42871	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03628\|UniProtKB=B6K4R6	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPBC1709.11c\|UniProtKB=O74736	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03230\|UniProtKB=B6K3P0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG02500\|UniProtKB=Q5KDX1	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNK01390\|UniProtKB=Q5K9N1	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03244\|UniProtKB=A0A0D1CPX3	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_03543\|UniProtKB=A0A0D1E1D5	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_11302\|UniProtKB=A0A0D1CY55	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_22441\|UniProtKB=H6QUG2	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_07538\|UniProtKB=E3KDD2	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11257\|UniProtKB=E3KLB3	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_35913\|UniProtKB=F4PAL3	Batrachochytrium dendrobatidis	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_48259\|UniProtKB=F0ZNF5	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00037638001\|UniProtKB=A0CEI3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035517001\|UniProtKB=A0C6H1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010382001\|UniProtKB=A0CTN1	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00034555001\|UniProtKB=A0C2R0	Paramecium tetraurelia	O
PHYRM\|Gene=H3GPF2_PHYRM\|UniProtKB=H3GPF2	Phytophthora ramorum	O
PHYRM\|Gene=H3G7E0_PHYRM\|UniProtKB=H3G7E0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g357650v5\|UniProtKB=A0A2K3DLR4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g668200v5\|UniProtKB=A0A2K3CUF1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00004p00078450\|UniProtKB=W1NEG4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_17G00310\|UniProtKB=A0A0K9PR70	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g08680\|UniProtKB=A0A804J2E0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_037150mg\|UniProtKB=K4AE43	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G090400\|UniProtKB=C5X153	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb057160\|UniProtKB=B4F827	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0748200\|UniProtKB=Q10CW4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_5g17460v3\|UniProtKB=I1J0A0	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_1g08690v3\|UniProtKB=I1GNB5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0510370\|UniProtKB=A0A8I6YV71	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G396600\|UniProtKB=A0A3B6MZ89	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G386800\|UniProtKB=A0A3B6KPJ0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G391700\|UniProtKB=A0A3B6LTG6	Triticum aestivum	LDO
NELNU\|Gene=LOC104606301\|UniProtKB=A0A1U8Q889	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110802219\|UniProtKB=A0A9R0KA79	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0510951\|UniProtKB=A0A251VDQ2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0037071\|UniProtKB=A0A251VQW3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C100024380\|UniProtKB=A0A9R1WK71	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a013805mg\|UniProtKB=A0A022Q9A5	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a012465mg\|UniProtKB=A0A022R1M1	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_06741\|UniProtKB=A0A2G3ABQ8	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_32766\|UniProtKB=A0A1U8EKV3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400008367\|UniProtKB=M1AFC8	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107762963\|UniProtKB=A0A1S3XAB5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi08g01824\|UniProtKB=D7TI56	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02091\|UniProtKB=A0A059DGH7	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra040776\|UniProtKB=A0A397ZKZ7	Brassica campestris	LDO
ARATH\|TAIR=locus=2020063\|UniProtKB=B3H615	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107942847\|UniProtKB=A0A1U8MZ32	Gossypium hirsutum	O
GOSHI\|Gene=LOC107888442\|UniProtKB=A0A1U8HPT8	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_026456\|UniProtKB=A0A061F9Q6	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g024980mg\|UniProtKB=A0A067EV14	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_013G058800v3\|UniProtKB=B9I5Y6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_019G033800v3\|UniProtKB=B9IPP2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_08G150000\|UniProtKB=A0A2C9VGG2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1121770\|UniProtKB=B9SHH0	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_19G110500\|UniProtKB=C6TJE0	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_16G041900\|UniProtKB=A0A0R0FL58	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_7g085450\|UniProtKB=A2Q5P5	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_00150\|UniProtKB=A0A2I4DUL2	Juglans regia	LDO
JUGRE\|Gene=LOC118348476\|UniProtKB=A0A6P9EF82	Juglans regia	O
JUGRE\|EnsemblGenome=Jr04_22550\|UniProtKB=A0A2I4GSV3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G192170\|UniProtKB=A0A0A0KWF6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_7G003300\|UniProtKB=M5VRL6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_154381\|UniProtKB=D8REZ2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_17740\|UniProtKB=A9T6D5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0099s0054\|UniProtKB=A0A2R6WF15	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003120030\|UniProtKB=A0A1Y1IDJ9	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001780090\|UniProtKB=A0A1Y1HZS1	Klebsormidium nitens	LDO