PANTHER Gene Information

Gene Symbol(s):

Mfsd2a

Organism:

Rattus norvegicus

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Gene Name:

Major facilitator superfamily domain containing 2A

Gene ID:

1310174

Protein ID:

B1WBW6

Persistent Id:

PTN000792827

Alternate Ids:

NM_001106683(refSeq)	B1WBW6_RAT(UniProtKB-ID)
ENSRNOT00000019080(Ensembl_TRS)	157821349(GI)
ENSRNOG00000014008(Ensembl)	B1WBW6(Synonym)
ENSRNOP00000019080(Ensembl_PRO)	298504(GeneID)
1310174(RGD)
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PANTHER Classification

PANTHER Family:	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN (PTHR11328)
PANTHER Subfamily:	SODIUM-DEPENDENT LYSOPHOSPHATIDYLCHOLINE SYMPORTER 1 (PTHR11328:SF29)
PANTHER GO-slim Molecular Function:	solute:sodium symporter activity phospholipid transporter activity carbohydrate derivative transmembrane transporter activity monocarboxylic acid transmembrane transporter activity
PANTHER GO-slim Biological Process:	carbohydrate derivative transport phospholipid translocation fatty acid transport circulatory system process
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	oleate transmembrane transporter activity, fatty acid transmembrane transporter activity, lysophosphatidylcholine flippase activity, symporter activity, lysophospholipid:sodium symporter activity, long-chain fatty acid transmembrane transporter activity
GO BP Complete:	regulation of multicellular organism growth, retina morphogenesis in camera-type eye, carbohydrate transport, regulation of dendrite development, positive regulation of cell growth, long-chain fatty acid transport, negative regulation of fatty acid beta-oxidation, fatty acid transport, transcytosis, cognition, regulation of phosphatidylcholine metabolic process, retinal pigment epithelium development, energy homeostasis, maintenance of blood-brain barrier, transmembrane transport, photoreceptor cell morphogenesis, regulation of neuron projection arborization, establishment of blood-brain barrier, hippocampus development, brain development, cellular response to starvation, regulation of phosphatidylethanolamine metabolic process, motor behavior, regulation of phosphatidylserine metabolic process, lipid transport across blood-brain barrier, positive regulation of triglyceride biosynthetic process, lysophospholipid translocation, very-low-density lipoprotein particle assembly, photoreceptor cell outer segment organization, lysophospholipid transport
GO CC Complete:	endoplasmic reticulum membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Phospholipid metabolism, Metabolism, Metabolism of lipids, Glycerophospholipid biosynthesis, Synthesis of PC

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25897\|UniProtKB=Q8NA29	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000581.7\|UniProtKB=K7CU99	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015275.3\|UniProtKB=G3RGZ3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011264.4\|UniProtKB=H9G0X9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923824\|UniProtKB=Q9DA75	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000013054.6\|UniProtKB=A6QQA1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000003669.5\|UniProtKB=F1SMC3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013728.4\|UniProtKB=F7ATY1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009858.6\|UniProtKB=A0A2I2UJ51	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011113.1\|UniProtKB=A0A8I3NTM8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017646.4\|UniProtKB=F6YKK1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000002711.3\|UniProtKB=F6UB84	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015097.1\|UniProtKB=A0A8V0YJN0	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00015023280\|UniProtKB=F1NCD6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004894.4\|UniProtKB=H9G9N2	Anolis carolinensis	LDO
XENLA\|Gene=mfsd2a.L\|UniProtKB=A5PKN7	Xenopus laevis	O
XENLA\|Gene=mfsd2a.S\|UniProtKB=A0A310TRD2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-951402\|UniProtKB=Q0IHM1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017199.2\|UniProtKB=H2MRZ0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000023807.1\|UniProtKB=H2MRY5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000005843.2\|UniProtKB=H2LMS8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041114-166\|UniProtKB=Q5U3U7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040801-89\|UniProtKB=Q6DEJ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002089.1\|UniProtKB=W5M234	lepisosteus oculatus	LDO
STRPU\|EnsemblGenome=LOC582692\|UniProtKB=A0A7M7NM89	Strongylocentrotus purpuratus	LDO
DICDI\|dictyBase=DDB_G0282159\|UniProtKB=Q54SX3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_50200\|UniProtKB=F0ZX93	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_324570\|UniProtKB=A2GB54	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_202220\|UniProtKB=A2DWP3	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_584690\|UniProtKB=A2GLK0	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0529200\|UniProtKB=Q8I3H5	Plasmodium falciparum	LDO
CHLAA\|EnsemblGenome=Caur_2083\|UniProtKB=A9WEY0	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_1783\|UniProtKB=A9WD33	Chloroflexus aurantiacus	LDO
BACSU\|EnsemblGenome=BSU_06160\|UniProtKB=O34368	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_17570\|UniProtKB=P94488	Bacillus subtilis	LDO
BACSU\|EnsemblGenome=BSU_12310\|UniProtKB=O34961	Bacillus subtilis	O
GLOVI\|Gene=Q7NEC1_GLOVI\|UniProtKB=Q7NEC1	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NDI5_GLOVI\|UniProtKB=Q7NDI5	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18257\|UniProtKB=P74168	Synechocystis	LDO
FUSNN\|EnsemblGenome=FN0222\|UniProtKB=Q8RGR4	Fusobacterium nucleatum	LDO
XANCP\|EnsemblGenome=XCC4121\|UniProtKB=Q8P3F0	Xanthomonas campestris	LDO
XANCP\|EnsemblGenome=XCC4078\|UniProtKB=Q8P3J3	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM4017\|UniProtKB=Q9L7R4	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO0995\|UniProtKB=A0A7Y8RHN7	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77433\|UniProtKB=P32136	Escherichia coli	O
SALTY\|EnsemblGenome=STM4299\|UniProtKB=P30878	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE78122\|UniProtKB=P02921	Escherichia coli	O
SALTY\|EnsemblGenome=STM4018\|UniProtKB=Q9L7R5	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA15367\|UniProtKB=P0CE44	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77432\|UniProtKB=P32137	Escherichia coli	O
SALTY\|EnsemblGenome=STM0149\|UniProtKB=H9L454	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM0042\|UniProtKB=Q8ZRZ1	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM4065\|UniProtKB=Q8ZKR3	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM3750\|UniProtKB=Q7CPH1	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO1226\|UniProtKB=Q0WHI1	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE76054\|UniProtKB=P75683	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77636\|UniProtKB=P31435	Escherichia coli	LDO