PANTHER Gene Information

Gene Symbol(s):

Cldn18

Organism:

Rattus norvegicus

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Gene Name:

Claudin-18

Gene ID:

1359696

Protein ID:

Q5I0E5

Persistent Id:

PTN000243753

Alternate Ids:

CH473954(EMBL)	EDL77432(EMBL-CDS)
CLD18(Synonym)	Cldn18{ECO:0000312\|RGD:1359696}(Symbol)
XP_006243691(refSeq)	F1LNR6(AltAccession)
315953(GeneID)	149018792(GI)
CLD18_RAT(UniProtKB-ID)	1359696(RGD)
ENSRNOG00000030386(Ensembl)
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PANTHER Classification

PANTHER Family:	CLAUDIN (PTHR12002)
PANTHER Subfamily:	CLAUDIN-18 (PTHR12002:SF9)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cell-cell junction assembly cell adhesion
PANTHER GO-slim Cellular Component:	plasma membrane bicellular tight junction
PANTHER protein class:	tight junction

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	structural molecule activity
GO BP Complete:	organ growth, negative regulation of protein localization to nucleus, epithelial fluid transport, cell adhesion, negative regulation of bone resorption, cellular response to estrogen stimulus, response to ethanol, lung alveolus development, epithelial cell proliferation, digestive tract development, negative regulation of tumor necrosis factor-mediated signaling pathway, bicellular tight junction assembly, tight junction assembly, tight junction organization, negative regulation of osteoclast development, protein localization to nucleus
GO CC Complete:	bicellular tight junction, tight junction, cell-cell junction, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2039\|UniProtKB=P56856	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000013633.3\|UniProtKB=G3RCR4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009636.4\|UniProtKB=F6YQY3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1929209\|UniProtKB=P56857	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000014589\|UniProtKB=Q0VCN0	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000009410.4\|UniProtKB=A0A5F5PYP0	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845023238.1\|UniProtKB=A0A8I3PMY9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018549.4\|UniProtKB=F7GCU7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000049325.1\|UniProtKB=A0A6I8P8K5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024572.1\|UniProtKB=A0A8V1A2G7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009163.4\|UniProtKB=G1KIJ7	Anolis carolinensis	LDO
XENLA\|Gene=cldn18.S\|UniProtKB=A0A1L8G5A2	Xenopus laevis	O
XENLA\|Gene=cldn18.L\|UniProtKB=A0A1L8GBU4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-991171\|UniProtKB=A0A6I8RHA0	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-130530-867\|UniProtKB=A0A0G2L7R9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006200.1\|UniProtKB=W5MGH9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020534.1\|UniProtKB=H2Y1V9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023118.1\|UniProtKB=H2XNH4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006335.3\|UniProtKB=F6PX91	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000466.3\|UniProtKB=F6YW52	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013927.2\|UniProtKB=F6PQC6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008241.3\|UniProtKB=F6R4U4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000021125.1\|UniProtKB=H2XJV5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018196.1\|UniProtKB=A0A1W5BNS4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009650.3\|UniProtKB=F6WVA9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004592.3\|UniProtKB=F6PSB3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020956.1\|UniProtKB=H2XV98	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_77360\|UniProtKB=C3Z150	Branchiostoma floridae	O