PANTHER Gene Information   
Gene Symbol(s): Ryr1
Organism: Rattus norvegicus
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Gene Name: Ryanodine receptor 1
Gene ID: 1586637
Protein ID: F1LMY4
Persistent Id: PTN000346478
Alternate Ids:
1586637(RGD) Skeletal muscle ryanodine receptor(Synonym)
AF011788(EMBL) Ryr1{ECO:0000312|RGD:1586637}(Symbol)
378523612(GI) AAD48899(EMBL-CDS)
RYR1_RAT(UniProtKB-ID) O35208(AltAccession)
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PANTHER Classification
PANTHER Family: B30.2/SPRY DOMAIN-CONTAINING PROTEIN (PTHR46399)
PANTHER Subfamily: RYANODINE RECEPTOR 1 (PTHR46399:SF10)  
PANTHER GO-slim Molecular Function: calcium channel activity
ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process: release of sequestered calcium ion into cytosol
striated muscle contraction
PANTHER GO-slim Cellular Component: bounding membrane of organelle
calcium channel complex
endoplasmic reticulum membrane
Z disc
sarcoplasmic reticulum
sarcolemma
PANTHER protein class:
Pathway Categories: Beta1 adrenergic receptor signaling pathway
   ER-type Ca2+ channel
CCKR signaling map
   RYR1/2/3
Beta2 adrenergic receptor signaling pathway
   ER-type Ca2+ channel

GO MF Complete: ATP binding, ryanodine-sensitive calcium-release channel activity, calmodulin binding, protein binding, calcium-induced calcium release activity, calcium channel activity, calcium ion binding, protease binding, voltage-gated calcium channel activity, enzyme binding
GO BP Complete: response to caloric restriction, outflow tract morphogenesis, striated muscle contraction, skin development, response to hypoxia, protein homotetramerization, skeletal muscle contraction, cellular response to calcium ion, skeletal muscle fiber development, muscle contraction, calcium ion transport, calcium ion transmembrane transport, release of sequestered calcium ion into cytosol, cellular response to caffeine, calcium-mediated signaling, response to electrical stimulus, cellular response to ATP, response to muscle activity, regulation of cytosolic calcium ion concentration, intracellular calcium ion homeostasis, ossification involved in bone maturation, regulation of response to osmotic stress, release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, sarcoplasmic reticulum calcium ion transport, response to estradiol, response to caffeine, negative regulation of transforming growth factor beta receptor signaling pathway
GO CC Complete: sarcoplasmic reticulum, smooth endoplasmic reticulum, organelle membrane, plasma membrane, cytoplasmic side of plasma membrane, Z disc, T-tubule, calcium channel complex, perinuclear region of cytoplasm, cytoplasm, cell cortex, sarcolemma, ryanodine receptor complex, membrane, extrinsic component of cytoplasmic side of plasma membrane, I band, vesicle, terminal cisterna, protein-containing complex, sarcomere, junctional membrane complex, sarcoplasmic reticulum membrane
Reactome Pathways: Muscle contraction, Ion channel transport, Stimuli-sensing channels, Transport of small molecules, Ion homeostasis, Cardiac conduction