PANTHER Gene Information

Gene Symbol(s):

Oca2

Organism:

Rattus norvegicus

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Gene Name:

OCA2 melanosomal transmembrane protein

Gene ID:

2318412

Protein ID:

Q4LEV3

Persistent Id:

PTN000815015

Alternate Ids:

407339767(GI)	AB191343(EMBL)
Q4LEV3_RAT(UniProtKB-ID)	NP_001258422(refSeq)
BAE03195(EMBL-CDS)	ENSRNOG00000014465(Ensembl)
ENSRNOT00000019498(Ensembl_TRS)	Q4LEV3(Synonym)
ENSRNOP00000019498(Ensembl_PRO)	2318412(RGD)
100365773(GeneID)
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PANTHER Classification

PANTHER Family:	P PROTEIN (PTHR43568)
PANTHER Subfamily:	P PROTEIN (PTHR43568:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	chloride channel activity
GO BP Complete:	cell population proliferation, biological_process, melanin biosynthetic process, developmental pigmentation, melanocyte differentiation, spermatid development, chloride transmembrane transport, pigmentation, melanin biosynthetic process from tyrosine, lysosomal lumen pH elevation
GO CC Complete:	endoplasmic reticulum membrane, melanosome membrane, endosome membrane, lysosomal membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Melanin biosynthesis, Metabolism, Metabolism of amino acids and derivatives

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8101\|UniProtKB=Q04671	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006834.6\|UniProtKB=A0A2I3TCV4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000005900.3\|UniProtKB=G3QSY0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012027.4\|UniProtKB=F7GY63	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97454\|UniProtKB=Q62052	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000009831.6\|UniProtKB=E1BA42	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000057372.1\|UniProtKB=A0A8W4FBC9	Sus scrofa	LDO
PIG\|Gene=Oca2\|UniProtKB=Q8MIQ9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009637.4\|UniProtKB=A0A3Q2H3M1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000153.6\|UniProtKB=M3VU67	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016997.1\|UniProtKB=A0A1Y6D565	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000700.4\|UniProtKB=F6WLQ8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000031582.2\|UniProtKB=A0A6I8PE97	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002896.1\|UniProtKB=A0A8V0XEN3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011098.4\|UniProtKB=G1KKX6	Anolis carolinensis	LDO
XENLA\|Gene=LOC108708435\|UniProtKB=A0A1L8HH36	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-989255\|UniProtKB=A0A6I8PWG6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015893.2\|UniProtKB=A0A3B3HU53	Oryzias latipes	LDO
DANRE\|Ensembl=ENSDARG00000114560.1\|UniProtKB=A0A2R8Q6Z4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000008282.1\|UniProtKB=W5MNX6	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118406957\|UniProtKB=A0A9J7KK19	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115922213\|UniProtKB=A0A7M7NLC2	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC575044\|UniProtKB=A0A7M7NGZ5	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0036329\|UniProtKB=Q9VU30	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0051693\|UniProtKB=Q7KRS1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0035332\|UniProtKB=Q9W024	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0031649\|UniProtKB=Q9VR48	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0041150\|UniProtKB=Q9VR47	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009283\|UniProtKB=A0A1S4H1G3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP009284\|UniProtKB=A0A1S4H0M1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015853\|UniProtKB=D2A4A9	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW012184\|UniProtKB=B7QBQ2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW019606\|UniProtKB=B7PWY8	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW005393\|UniProtKB=B7PPP5	Ixodes scapularis	LDO
IXOSC\|EnsemblGenome=ISCW012165\|UniProtKB=B7QEJ7	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122951\|UniProtKB=A7SLS9	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_29712\|UniProtKB=A9VBW9	Monosiga brevicollis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_262258\|UniProtKB=B8C016	Thalassiosira pseudonana	LDO
RICCO\|Gene_ORFName=RCOM_2056740\|UniProtKB=B9TKL1	Ricinus communis	LDO
MYCTU\|Gene_OrderedLocusName=Rv2685\|UniProtKB=P9WPD7	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv2684\|UniProtKB=P9WPD9	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO0497\|UniProtKB=A5HZ42	Clostridium botulinum	LDO
BACCR\|EnsemblGenome=BC_3463\|UniProtKB=Q81AU3	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_3117\|UniProtKB=Q81BN5	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_4911\|UniProtKB=Q816E9	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1045\|UniProtKB=Q9X0D5	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_0934\|UniProtKB=Q9X032	Thermotoga maritima	LDO
SYNY3\|EnsemblGenome=BAA18751\|UniProtKB=P74635	Synechocystis	LDO
RHOBA\|EnsemblGenome=RB6716\|UniProtKB=Q7UPU4	Rhodopirellula baltica	LDO
THEYD\|EnsemblGenome=THEYE_A0731\|UniProtKB=B5YK08	Thermodesulfovibrio yellowstonii	LDO
FUSNN\|EnsemblGenome=FN1924\|UniProtKB=Q8RHS4	Fusobacterium nucleatum	O
FUSNN\|EnsemblGenome=FN1925\|UniProtKB=Q8RHS3	Fusobacterium nucleatum	LDO
SALTY\|EnsemblGenome=STM0836\|UniProtKB=Q8ZQN1	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAA35499\|UniProtKB=P75788	Escherichia coli	LDO