PANTHER Gene Information

Gene Symbol(s):

Ear1

Organism:

Rattus norvegicus

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Gene Name:

Eosinophil-associated, ribonuclease A family, member 1

Gene ID:

2324564

Protein ID:

E9PU07

Persistent Id:

PTN000893250

Alternate Ids:

E9PU07_RAT(UniProtKB-ID)	XM_002728193(refSeq)
ENSRNOP00000021645(Ensembl_PRO)	100361909(GeneID)
2324564(RGD)	293353587(GI)
ENSRNOG00000062969(Ensembl)	ENSRNOT00000021645(Ensembl_TRS)
CDG32039(EMBL-CDS)	HG328963(EMBL)
E9PU07(Synonym)
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PANTHER Classification

PANTHER Family:	RIBONUCLEASE (PTHR11437)
PANTHER Subfamily:	EOSINOPHIL CATIONIC PROTEIN (PTHR11437:SF3)
PANTHER GO-slim Molecular Function:	RNA nuclease activity
PANTHER GO-slim Biological Process:	defense response to Gram-positive bacterium chemotaxis innate immune response
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	endoribonuclease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleic acid binding, endonuclease activity, RNA nuclease activity
GO BP Complete:	chemotaxis, innate immune response in mucosa, defense response to Gram-positive bacterium
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neutrophil degranulation, Immune System, Innate Immune System, Antimicrobial peptides

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10045\|UniProtKB=P10153	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000006106\|UniProtKB=P47785	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000043975\|UniProtKB=P47782	Gorilla gorilla gorilla	O
HUMAN\|HGNC=10046\|UniProtKB=P12724	Homo sapiens	LDO
PANTR\|Gene=RNASE3\|UniProtKB=P47780	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000037139\|UniProtKB=P47778	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000057298.1\|UniProtKB=F7CXX5	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000056509.1\|UniProtKB=F7GKX7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1890464\|UniProtKB=Q923L6	Mus musculus	O
MOUSE\|MGI=MGI=3528616\|UniProtKB=F6YUX7	Mus musculus	O
MOUSE\|MGI=MGI=1890465\|UniProtKB=Q8K196	Mus musculus	LDO
MOUSE\|MGI=MGI=108020\|UniProtKB=P97425	Mus musculus	O
MOUSE\|MGI=MGI=1858237\|UniProtKB=O35290	Mus musculus	O
MOUSE\|MGI=MGI=1890463\|UniProtKB=Q923L7	Mus musculus	O
MOUSE\|MGI=MGI=1858598\|UniProtKB=O35292	Mus musculus	O
MOUSE\|MGI=MGI=108021\|UniProtKB=P97426	Mus musculus	O
MOUSE\|MGI=MGI=1858238\|UniProtKB=O35291	Mus musculus	O
BOVIN\|Ensembl=ENSBTAG00000025664.5\|UniProtKB=F1MGC2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049914.1\|UniProtKB=A0A3Q1LIW8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005022353.1\|UniProtKB=A0A287AE25	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000002332.3\|UniProtKB=F6UTM9	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000050142.1\|UniProtKB=A0A5F8G595	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000024491.1\|UniProtKB=F7E3I3	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000007034.3\|UniProtKB=F7E387	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000045391.1\|UniProtKB=A0A5F8GQE1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001916.2\|UniProtKB=F6ZXU1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010008443\|UniProtKB=P30374	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010011433\|UniProtKB=P27043	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010002667.1\|UniProtKB=A0A8V0X6Y3	Gallus gallus	O
CHICK\|Gene=RNL2_CHICK\|UniProtKB=P81476	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007894.3\|UniProtKB=H9GD65	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000036212.1\|UniProtKB=A0A803T5A2	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000039056.1\|UniProtKB=A0A803TLP8	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000043896.1\|UniProtKB=H9GAD6	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000039552.1\|UniProtKB=A0A803SKJ8	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000038211.1\|UniProtKB=H9GAD8	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000006418.2\|UniProtKB=H2LPS5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022214.1\|UniProtKB=A0A3B3I9G7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029417.1\|UniProtKB=A0A3B3HT95	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029156.1\|UniProtKB=A0A3B3H7B7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029743.1\|UniProtKB=A0A3B3I5P0	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000022465.1\|UniProtKB=A0A3B3HMY3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000025191.1\|UniProtKB=A0A3B3IDR8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000030644.1\|UniProtKB=A0A3B3HSH1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050809-5\|UniProtKB=A5HAK0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050208-420\|UniProtKB=A5HAK1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017307.1\|UniProtKB=W5NLA3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000001488.1\|UniProtKB=W5M017	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000017306.1\|UniProtKB=W5NLA2	lepisosteus oculatus	O