PANTHER Gene Information

Gene Symbol(s):

Kcnc1

Organism:

Rattus norvegicus

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Gene Name:

Potassium voltage-gated channel subfamily C member 1

Gene ID:

2955

Protein ID:

P25122

Persistent Id:

PTN000165555

Alternate Ids:

39978334(GI)	25327(GeneID)
X62840(EMBL)	ENSRNOG00000055401(Ensembl)
Voltage-gated potassium channel subunit Kv4(Synonym)	AAA41501(EMBL-CDS)
CHEMBL2321617(ChEMBL)	2955(RGD)
Kcnc1(Symbol)	KCNC1_RAT(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	VOLTAGE-GATED POTASSIUM CHANNEL (PTHR11537)
PANTHER Subfamily:	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 1 (PTHR11537:SF87)
PANTHER GO-slim Molecular Function:	delayed rectifier potassium channel activity
PANTHER GO-slim Biological Process:	potassium ion transmembrane transport action potential
PANTHER GO-slim Cellular Component:	voltage-gated potassium channel complex neuronal cell body postsynaptic membrane presynaptic membrane cell projection membrane axon terminus leading edge membrane dendrite
PANTHER protein class:	voltage-gated ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	voltage-gated potassium channel activity, protein binding, metal ion binding, delayed rectifier potassium channel activity, kinesin binding, voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential, transmembrane transporter binding
GO BP Complete:	positive regulation of potassium ion transmembrane transport, potassium ion transmembrane transport, cerebellum development, response to amine, globus pallidus development, protein homooligomerization, response to light intensity, regulation of potassium ion transmembrane transport, response to toxic substance, optic nerve development, corpus callosum development, positive regulation of voltage-gated potassium channel activity, response to nerve growth factor, protein tetramerization, response to auditory stimulus, regulation of monoatomic ion transmembrane transport, action potential, cellular response to xenobiotic stimulus, response to fibroblast growth factor, regulation of presynaptic membrane potential, positive regulation of monoatomic ion transmembrane transport, response to potassium ion
GO CC Complete:	presynaptic membrane, dendrite, dendrite membrane, postsynaptic membrane, voltage-gated potassium channel complex, axolemma, neuronal cell body membrane, neuronal cell body, axon terminus, cell surface, neuron projection membrane, calyx of Held

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Potassium Channels, Neuronal System, Voltage gated Potassium channels

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6233\|UniProtKB=P48547	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003407.6\|UniProtKB=H2Q386	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015717.3\|UniProtKB=G3RI47	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006403.4\|UniProtKB=F7GWN3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96667\|UniProtKB=P15388	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000005424.4\|UniProtKB=F1N553	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000013374.5\|UniProtKB=A0A287BDS8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000002236.3\|UniProtKB=F6V9F7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004974.5\|UniProtKB=M3W381	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000006734.4\|UniProtKB=F7CX06	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003052.3\|UniProtKB=F7B029	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024401.1\|UniProtKB=A0A8V0ZS84	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000055.4\|UniProtKB=G1K883	Anolis carolinensis	LDO
XENLA\|Gene=LOC108713698\|UniProtKB=A0A8J0V045	Xenopus laevis	O
XENLA\|Gene=LOC108715325\|UniProtKB=A0A1L8GEI7	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000005924.2\|UniProtKB=H2LN22	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-080414-3\|UniProtKB=F1Q4T7	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-061220-10\|UniProtKB=E0R7P5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006708.1\|UniProtKB=W5MI89	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014509.2\|UniProtKB=F6TMZ9	Ciona intestinalis	O
STRPU\|EnsemblGenome=LOC584187\|UniProtKB=A0A7M7P2Y7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004793\|UniProtKB=A0A3B1E007	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09488\|UniProtKB=A8X902	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278607\|UniProtKB=A0A2A6BWK5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008819\|UniProtKB=G5EC00	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00686\|UniProtKB=A8WNA6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109962\|UniProtKB=A0A2A6B8Z9	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00001202\|UniProtKB=G5EFC3	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00107109\|UniProtKB=A0A2A6B4U4	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0085395\|UniProtKB=A8DYR5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008202\|UniProtKB=A0A1S4GXL1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006642\|UniProtKB=D6WY23	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_44795\|UniProtKB=E9G2I2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_46499\|UniProtKB=E9G6G5	Daphnia pulex	O
DROME\|FlyBase=FBgn0003386\|UniProtKB=P17972	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008201\|UniProtKB=A0A1S4GXK3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP029240\|UniProtKB=A0A453YZ55	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006643\|UniProtKB=D6WY24	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_110446\|UniProtKB=E9H699	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW022993\|UniProtKB=B7QM66	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW006705\|UniProtKB=B7PPC8	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG92607\|UniProtKB=T1G8I9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG64770\|UniProtKB=T1FXY9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG75592\|UniProtKB=T1G267	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG63495\|UniProtKB=T1FXG5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG92925\|UniProtKB=T1G8N9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244196\|UniProtKB=A7SBV3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g21646\|UniProtKB=A7S0S6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209875\|UniProtKB=A7SBV4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g84068\|UniProtKB=A7RJY3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g104830\|UniProtKB=A7S4T1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208335\|UniProtKB=A7S8A5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228740\|UniProtKB=A7RTZ3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208071\|UniProtKB=A7S7P7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208336\|UniProtKB=A7S8A6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g114311\|UniProtKB=A7SDJ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g40487\|UniProtKB=A7RJZ5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243646\|UniProtKB=A7S8V6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213684\|UniProtKB=A7SKI2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218492\|UniProtKB=A7SWC0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210189\|UniProtKB=A7SCL7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g201105\|UniProtKB=A7RRN5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205988\|UniProtKB=A7S300	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247709\|UniProtKB=A7SVV4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g84119\|UniProtKB=A7RJZ6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g197698\|UniProtKB=A7RIP6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200301\|UniProtKB=A7RPU3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109242\|UniProtKB=A7S8W8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG1922\|UniProtKB=B3RLA1	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_8918\|UniProtKB=A9V1I5	Monosiga brevicollis	O
CRYNJ\|EnsemblGenome=CNB01080\|UniProtKB=Q5KMN4	Cryptococcus neoformans	O
PLAF7\|EnsemblGenome=PF3D7_1227200\|UniProtKB=Q8I5E6	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00032334001\|UniProtKB=A0BU85	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025187001\|UniProtKB=A0EAY6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003436001\|UniProtKB=A0E5K8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000712001\|UniProtKB=A0CJN3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000081001\|UniProtKB=Q6BFH0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000998001\|UniProtKB=A0CKG7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009073001\|UniProtKB=A0CPG4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029282001\|UniProtKB=A0BI79	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_3601\|UniProtKB=B8BY88	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_25101\|UniProtKB=B8LCD0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GVD0_PHYRM\|UniProtKB=H3GVD0	Phytophthora ramorum	O
PHYRM\|Gene=H3GVB5_PHYRM\|UniProtKB=H3GVB5	Phytophthora ramorum	O
PHYRM\|Gene=H3GS39_PHYRM\|UniProtKB=H3GS39	Phytophthora ramorum	O
PHYRM\|Gene=H3HCU8_PHYRM\|UniProtKB=H3HCU8	Phytophthora ramorum	O
PHYRM\|Gene=H3HCR2_PHYRM\|UniProtKB=H3HCR2	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g022150v5\|UniProtKB=A8HPX4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g432550v5\|UniProtKB=A8IB39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_11g468353v5\|UniProtKB=A0A2K3D845	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g330400v5\|UniProtKB=A0A2K3DJW6	Chlamydomonas reinhardtii	O
THEKO\|EnsemblGenome=TK1300\|UniProtKB=Q5JGQ8	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_0221\|UniProtKB=A9WC81	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO7196\|UniProtKB=Q9FBY6	Streptomyces coelicolor	O
LISMO\|Gene=Q8Y5K1_LISMO\|UniProtKB=Q8Y5K1	Listeria monocytogenes	O
DEIRA\|EnsemblGenome=DR_0830\|UniProtKB=Q9RW39	Deinococcus radiodurans	O
BACTN\|EnsemblGenome=BT_2572\|UniProtKB=Q8A4M7	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_4486\|UniProtKB=Q89Z91	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB12424\|UniProtKB=Q7UIN7	Rhodopirellula baltica	O
BRADU\|Gene=Q89CE1_BRADU\|UniProtKB=Q89CE1	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89I90_BRADU\|UniProtKB=Q89I90	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC3283\|UniProtKB=Q8P5Q3	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1496\|UniProtKB=Q9I3L6	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM1741\|UniProtKB=Q8ZP47	Salmonella typhimurium	O