PANTHER Gene Information   
Gene Symbol(s): Slc22a1
Organism: Rattus norvegicus
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Gene Name: Solute carrier family 22 member 1
Gene ID: 3224
Protein ID: Q63089
Persistent Id: PTN002782749
Alternate Ids:
81872095(GI) AAB67702(EMBL-CDS)
O35882(AltAccession) S22A1_RAT(UniProtKB-ID)
BC078883(EMBL) Oct1(Synonym)
3224(RGD) CHEMBL2073670(ChEMBL)
Slc22a1{ECO:0000312|RGD:3224}(Symbol) 24904(GeneID)
ENSRNOG00000016337(Ensembl)
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PANTHER Classification
PANTHER Family: SOLUTE CARRIER FAMILY 22 MEMBER (PTHR24064)
PANTHER Subfamily: SOLUTE CARRIER FAMILY 22 MEMBER 1 (PTHR24064:SF291)  
PANTHER GO-slim Molecular Function: organic cation transmembrane transporter activity
PANTHER GO-slim Biological Process: organic cation transport
PANTHER GO-slim Cellular Component:
PANTHER protein class: secondary carrier transporter
Pathway Categories: No pathway information available
GO MF Complete: pyrimidine nucleoside transmembrane transporter activity, putrescine transmembrane transporter activity, xenobiotic transmembrane transporter activity, thiamine transmembrane transporter activity, identical protein binding, organic cation transmembrane transporter activity, quaternary ammonium group transmembrane transporter activity, prostaglandin transmembrane transporter activity, dopamine:sodium symporter activity, (R)-carnitine transmembrane transporter activity, acetylcholine transmembrane transporter activity, norepinephrine:sodium symporter activity, monoamine transmembrane transporter activity, organic anion transmembrane transporter activity, neurotransmitter transmembrane transporter activity, spermidine transmembrane transporter activity, toxin transmembrane transporter activity
GO BP Complete: norepinephrine transport, quaternary ammonium group transport, dopamine transport, organic cation transport, acetylcholine transport, dopamine uptake, acyl carnitine transmembrane transport, norepinephrine uptake, neurotransmitter transport, epinephrine transport, monoatomic cation transport, xenobiotic transport across blood-brain barrier, serotonin transport, monoatomic cation transmembrane transport, spermidine transport, putrescine transport, cellular detoxification, thiamine transmembrane transport, monoamine transport, thiamine transport, (R)-carnitine transmembrane transport, spermidine transmembrane transport, serotonin uptake, establishment or maintenance of transmembrane electrochemical gradient, xenobiotic transport, metanephric proximal tubule development, prostaglandin transport
GO CC Complete: basal plasma membrane, lateral plasma membrane, presynapse, basolateral plasma membrane, plasma membrane, apical plasma membrane
Reactome Pathways: Abacavir transmembrane transport, Neurotransmitter clearance, Neurotransmitter release cycle, Norepinephrine Neurotransmitter Release Cycle, Organic cation transport, Drug ADME, Abacavir ADME, Neuronal System, Transmission across Chemical Synapses, Ciprofloxacin ADME, Na+/Cl- dependent neurotransmitter transporters, Transport of bile salts and organic acids, metal ions and amine compounds, Transport of small molecules, Organic cation/anion/zwitterion transport, SLC-mediated transmembrane transport