PANTHER Gene Information

Gene Symbol(s):

Cfi

Organism:

Rattus norvegicus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Complement factor I

Gene ID:

620429

Protein ID:

Q9WUW3

Persistent Id:

PTN001546808

Alternate Ids:

CAB41688(EMBL-CDS)	BC089798(EMBL)
620429(RGD)	13162353(GI)
CFAI_RAT(UniProtKB-ID)	C3B/C4B inactivator(Synonym)
NM_024157(refSeq)	Q5EBC4(AltAccession)
79126(GeneID)	3.4.21.45(EC)
Cfi(Symbol)
Show All

PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	COMPLEMENT FACTOR I (PTHR24253:SF91)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metal ion binding, serine-type endopeptidase activity
GO BP Complete:	complement activation, cellular response to interleukin-6, complement activation, classical pathway, innate immune response, proteolysis
GO CC Complete:	extracellular space, membrane, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Complement cascade, Immune System, Innate Immune System, Regulation of Complement cascade

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5394\|UniProtKB=P05156	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000031127.5\|UniProtKB=K7ABU9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003371.4\|UniProtKB=A0A2I2Y2K4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000021226.4\|UniProtKB=F7HTT9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=105937\|UniProtKB=Q61129	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000034501.4\|UniProtKB=A0A3Q1MF14	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000009138.6\|UniProtKB=A0A287AQ20	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013869.4\|UniProtKB=A0A9L0RE17	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000105.6\|UniProtKB=A0A2I2U350	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029982.1\|UniProtKB=A0A8I3Q318	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005914.4\|UniProtKB=F6R2B1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000003664.3\|UniProtKB=F7E768	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003845.1\|UniProtKB=A0A8V0XKE8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000029395.2\|UniProtKB=R4G924	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000010059.4\|UniProtKB=G1KJP9	Anolis carolinensis	LDO
XENLA\|Gene=cfi.L\|UniProtKB=Q03711	Xenopus laevis	O
XENLA\|Gene=cfi.S\|UniProtKB=Q7ZTR2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5953276\|UniProtKB=Q4V785	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002364.2\|UniProtKB=H2LAM8	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000012242.1\|UniProtKB=W5N354	lepisosteus oculatus	LDO
ANOGA\|EnsemblGenome=AGAP028218\|UniProtKB=A0A1S4HEF2	Anopheles gambiae	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	O