PANTHER Gene Information

Gene Symbol(s):

Thbs4

Organism:

Rattus norvegicus

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Gene Name:

Thrombospondin-4

Gene ID:

62046

Protein ID:

P49744

Persistent Id:

PTN000023727

Alternate Ids:

CAA62002(EMBL-CDS)	TSP4(Synonym)
TSP4_RAT(UniProtKB-ID)	Thbs4(Symbol)
929835(GI)	62046(RGD)
X89963(EMBL)
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PANTHER Classification

PANTHER Family:	THROMBOSPONDIN (PTHR10199)
PANTHER Subfamily:	THROMBOSPONDIN-4 (PTHR10199:SF92)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	collagen-containing extracellular matrix
PANTHER protein class:	cell adhesion molecule

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	growth factor activity, identical protein binding, collagen binding, calcium ion binding, fibronectin binding, integrin binding, heparin binding, laminin-1 binding
GO BP Complete:	negative regulation of angiogenesis, signal transduction, positive regulation of neutrophil chemotaxis, nervous system development, neuron projection morphogenesis, cell adhesion, response to unfolded protein, tissue remodeling, myoblast migration, positive regulation of cell division, behavioral response to pain, regulation of tissue remodeling, positive regulation of endothelial cell proliferation, response to endoplasmic reticulum stress, positive regulation of peptidyl-tyrosine phosphorylation, endothelial cell-cell adhesion
GO CC Complete:	basement membrane, extracellular space, sarcoplasmic reticulum, collagen-containing extracellular matrix, endoplasmic reticulum, neuromuscular junction, extracellular region

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signaling by PDGF, Signaling by Receptor Tyrosine Kinases, Signal Transduction

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11788\|UniProtKB=P35443	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017031.6\|UniProtKB=H2QR56	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000027002.2\|UniProtKB=G3SD95	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003143.4\|UniProtKB=F7EPG2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1101779\|UniProtKB=Q9Z1T2	Mus musculus	LDO
BOVIN\|Gene=THBS4\|UniProtKB=Q3SWW8	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000012866.6\|UniProtKB=A0A452DJ62	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000014117.5\|UniProtKB=A0A5G2QTC8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019665.4\|UniProtKB=F7E0P3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003879.6\|UniProtKB=M3W148	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006098.1\|UniProtKB=A0A8I3MW94	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019706.4\|UniProtKB=F6TBV7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000044275.1\|UniProtKB=A0A6I8PBP0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010122.1\|UniProtKB=F1NBP0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016545.4\|UniProtKB=A0A803TQZ9	Anolis carolinensis	LDO
XENLA\|Gene=thbs4.S\|UniProtKB=Q6DE79	Xenopus laevis	O
XENLA\|Gene=thbs4\|UniProtKB=Q06441	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1008367\|UniProtKB=Q08D10	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008957.2\|UniProtKB=H2LYL4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-080215-11\|UniProtKB=A0A0R4I9N1	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000004949.2\|UniProtKB=H2LJP8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-020708-4\|UniProtKB=Q8JGW0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006036.1\|UniProtKB=W5MFY7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008607.3\|UniProtKB=F6TNY6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000002742.3\|UniProtKB=F6T2M3	Ciona intestinalis	O
BRAFL\|Gene=LOC118424195\|UniProtKB=A0A9J7N3D6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406477\|UniProtKB=A0A9J7HMR6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424189\|UniProtKB=A0A9J7LUX3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407522\|UniProtKB=A0A9J7HQ75	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407525\|UniProtKB=A0A9J7HQD1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407520\|UniProtKB=A0A9J7KKQ5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407973\|UniProtKB=A0A9J7HU68	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413002\|UniProtKB=A0A9J7KYE3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424184\|UniProtKB=A0A9J7LUB6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406912\|UniProtKB=A0A9J7HRR9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC576669\|UniProtKB=A0A7M7N867	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0038181\|UniProtKB=Q8I0D4	Drosophila melanogaster	O
HELRO\|EnsemblGenome=HelroG161577\|UniProtKB=T1ERN0	helobdella robusta	O
DROME\|FlyBase=FBgn0031850\|UniProtKB=Q9VM97	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002157\|UniProtKB=Q7QK54	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033883\|UniProtKB=A0A139WE83	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_213033\|UniProtKB=E9GPT7	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW006623\|UniProtKB=B7PKY4	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g222681\|UniProtKB=A7T5P7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168100\|UniProtKB=A7S9R9	Nematostella vectensis	O