PANTHER Gene Information

Gene Symbol(s):

Doc2b

Organism:

Rattus norvegicus

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Gene Name:

Double C2-like domain-containing protein beta

Gene ID:

620519

Protein ID:

P70610

Persistent Id:

PTN000002071

Alternate Ids:

U70778(EMBL)	AAB47747(EMBL-CDS)
541881710(GI)	DOC2B(Synonym)
DOC2B_RAT(UniProtKB-ID)	81820(GeneID)
620519(RGD)	NM_031142(refSeq)
Doc2b(Symbol)
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PANTHER Classification

PANTHER Family:	RABPHILIN, ISOFORM A (PTHR45729)
PANTHER Subfamily:	DOUBLE C2-LIKE DOMAIN-CONTAINING PROTEIN BETA (PTHR45729:SF9)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	exocytosis regulation of exocytosis neurotransmitter secretion
PANTHER GO-slim Cellular Component:	synapse
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	syntaxin binding, metal ion binding, calcium ion binding, calcium-dependent phospholipid binding
GO BP Complete:	calcium ion-regulated exocytosis of neurotransmitter, positive regulation of vesicle fusion, calcium-dependent activation of synaptic vesicle fusion, protein localization, spontaneous neurotransmitter secretion, positive regulation of insulin secretion, exocytosis, positive regulation of calcium ion-dependent exocytosis, neurotransmitter secretion
GO CC Complete:	extrinsic component of synaptic vesicle membrane, presynapse, cytoplasm, membrane, SNARE complex, synapse, glutamatergic synapse, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2986\|UniProtKB=Q14184	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000034564.3\|UniProtKB=H2RB74	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000025264.2\|UniProtKB=G3RXD2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005222.4\|UniProtKB=F7C329	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1100497\|UniProtKB=P70169	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000025140.5\|UniProtKB=F1N0W4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039412.3\|UniProtKB=A0A287BHY3	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000022608.4\|UniProtKB=M3X3X2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013995.1\|UniProtKB=A0A8I3NUH3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000038227.1\|UniProtKB=A0A5F8GB72	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000036409.1\|UniProtKB=A0A6I8NBR6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029778.1\|UniProtKB=E1BVF7	Gallus gallus	LDO
XENLA\|Gene=doc2b.L\|UniProtKB=A0A1L8HG28	Xenopus laevis	O
XENLA\|Gene=doc2b.S\|UniProtKB=A0A8J1ME98	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6032690\|UniProtKB=A0A6I8QM45	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000023518.1\|UniProtKB=A0A3B3I6V2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-081104-451\|UniProtKB=B0V2S0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006958.1\|UniProtKB=W5MJ63	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000020889.2\|UniProtKB=H2LY63	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000462.2\|UniProtKB=H2L484	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000189.2\|UniProtKB=A0A3B3H5N7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000015189.2\|UniProtKB=A0A3B3ICE7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090615-1\|UniProtKB=A0A8M6YYK0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002007.1\|UniProtKB=W5M1R9	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118425793\|UniProtKB=A0A9J7LYT5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115926813\|UniProtKB=A0A7M7PBS5	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004316\|UniProtKB=P41885	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036477\|UniProtKB=A8XPI5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090434\|UniProtKB=A0A2A6BP17	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0030230\|UniProtKB=Q9W2R9	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC015653\|UniProtKB=D2A657	Tribolium castaneum	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g206051\|UniProtKB=A7S352	Nematostella vectensis	O
TRIAD\|Gene_ORFName=TRIADDRAFT_59690\|UniProtKB=B3S664	Trichoplax adhaerens	O