PANTHER Gene Information   
Gene Symbol(s): Mmp3
Organism: Rattus norvegicus
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Gene Name: Stromelysin-1
Gene ID: 621317
Protein ID: P03957
Persistent Id: PTN000024092
Alternate Ids:
3.4.24.17 {ECO:0000269|PubMed:1963430, ECO:0000269|PubMed:1988438, ECO:0000269|PubMed:2841336}(EC) X02601(EMBL)
621317(RGD) 57461(GI)
MMP3(Synonym) MMP3_RAT(UniProtKB-ID)
CAA26448(EMBL-CDS) Mmp3(Symbol)
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PANTHER Classification
PANTHER Family: MATRIX METALLOPROTEINASE (PTHR10201)
PANTHER Subfamily: STROMELYSIN-1 (PTHR10201:SF215)  
PANTHER GO-slim Molecular Function: metalloendopeptidase activity
PANTHER GO-slim Biological Process: catabolic process
extracellular matrix organization
PANTHER GO-slim Cellular Component:
PANTHER protein class: metalloprotease
Pathway Categories: CCKR signaling map
   MMP3
Plasminogen activating cascade
   Matrix metalloprotease 3
Plasminogen activating cascade
   pro-Matrix metalloprotease 3

GO MF Complete: zinc ion binding, endopeptidase activity, peptidase activity, metalloendopeptidase activity, metallopeptidase activity, protein-containing complex binding
GO BP Complete: response to cytokine, protein catabolic process, response to amino acid, female pregnancy, response to mechanical stimulus, cellular response to cell-matrix adhesion, cellular response to amino acid stimulus, response to hypoxia, cellular response to UV-A, innate immune response, proteolysis, extracellular matrix organization, response to estradiol, response to interleukin-1, cellular response to interleukin-1, collagen catabolic process, response to lipopolysaccharide, regulation of cell migration, cellular response to reactive oxygen species, positive regulation of protein-containing complex assembly, positive regulation of cell migration, response to tumor necrosis factor, negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, negative regulation of reactive oxygen species metabolic process
GO CC Complete: dendrite, extracellular space, mitochondrion, cell body, cytosol, protein-containing complex, extracellular matrix, extracellular region
Reactome Pathways: Signaling by GPCR, Activation of Matrix Metalloproteinases, ESR-mediated signaling, Collagen formation, Extra-nuclear estrogen signaling, Signal Transduction, Assembly of collagen fibrils and other multimeric structures, EGFR Transactivation by Gastrin, Extracellular matrix organization, Gastrin-CREB signalling pathway via PKC and MAPK, Degradation of the extracellular matrix, GPCR downstream signalling, Signaling by Nuclear Receptors, G alpha (q) signalling events, Collagen degradation