PANTHER Gene Information

Gene Symbol(s):

Klkb1

Organism:

Rattus norvegicus

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Gene Name:

Plasma kallikrein

Gene ID:

67382

Protein ID:

P14272

Persistent Id:

PTN000668689

Alternate Ids:

Klk3(Synonym)	3.4.21.34(EC)
67382(RGD)	CHEMBL4105792(ChEMBL)
205011(GI)	M58590(EMBL)
AAA42069(EMBL-CDS)	Klkb1(Symbol)
KLKB1_RAT(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	PLASMA KALLIKREIN (PTHR24253:SF64)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

Blood coagulation

Prekallikrein

Blood coagulation

kallikrein

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	serine-type endopeptidase activity
GO BP Complete:	inflammatory response, liver regeneration, positive regulation of fibrinolysis, plasminogen activation, blood coagulation, fibrinolysis
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Degradation of the extracellular matrix, Formation of Fibrin Clot (Clotting Cascade), Activation of Matrix Metalloproteinases, Intrinsic Pathway of Fibrin Clot Formation, Hemostasis, Extracellular matrix organization

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6371\|UniProtKB=P03952	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000048789.1\|UniProtKB=A0A2I3TJS6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000026546.2\|UniProtKB=G3RZ73	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011633.4\|UniProtKB=A0A1D5Q7U7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=102849\|UniProtKB=P26262	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000009501\|UniProtKB=Q2KJ63	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005037241.1\|UniProtKB=A0A8D1M4K5	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000031525.4\|UniProtKB=A0A5F5XC24	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019450.1\|UniProtKB=A0A5K1VKB9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004972.4\|UniProtKB=A0A5F8GV34	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043904.1\|UniProtKB=A0A6I8P844	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010015065.1\|UniProtKB=A0A8V0YQV6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001300.4\|UniProtKB=G1K9G8	Anolis carolinensis	O
XENLA\|Gene=klkb1.L\|UniProtKB=A0A8J1M5A3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-985051\|UniProtKB=F6YRB8	Xenopus tropicalis	O
DANRE\|ZFIN=ZDB-GENE-040426-834\|UniProtKB=F1RBG3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015110.1\|UniProtKB=W5ND89	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000006898.2\|UniProtKB=H2LRG8	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000006813.1\|UniProtKB=W5MIL9	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000003449.3\|UniProtKB=F6WXY4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020629.1\|UniProtKB=H2XQG4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000012084.2\|UniProtKB=F6XVK2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001370.3\|UniProtKB=F6S9V9	Ciona intestinalis	O
BRAFL\|Gene=LOC118407680\|UniProtKB=A0A9J7HQK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406062\|UniProtKB=A0A9J7HLJ5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC594731\|UniProtKB=A0A7M7SZC5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC756308\|UniProtKB=A0A7M7P3U8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC588084\|UniProtKB=A0A7M7SZU0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890793\|UniProtKB=A0A7M7NU74	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC753460\|UniProtKB=A0A7M7P0R8	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00206066\|UniProtKB=A0A2A6BXF2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0033363\|UniProtKB=A1Z7M5	Drosophila melanogaster	O
TRICA\|EnsemblGenome=TC008657\|UniProtKB=D6WT56	Tribolium castaneum	O
DROME\|FlyBase=FBgn0033365\|UniProtKB=A1Z7M7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009000\|UniProtKB=A0A1S4H0L6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008653\|UniProtKB=D6WT60	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_49881\|UniProtKB=E9GFB8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW012701\|UniProtKB=B7QAI1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW015718\|UniProtKB=B7P1X4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001619\|UniProtKB=B7P4W5	Ixodes scapularis	O
DROME\|FlyBase=FBgn0286782\|UniProtKB=B7YZU2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008995\|UniProtKB=A0A1S4GZT1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033856\|UniProtKB=A0A139WEY0	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW001620\|UniProtKB=B7P4W6	Ixodes scapularis	O
DROME\|FlyBase=FBgn0035501\|UniProtKB=Q9VZH5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002811\|UniProtKB=A0A1S4GG73	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP013089\|UniProtKB=F5HKL0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP002813\|UniProtKB=Q7QCV0	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_226573\|UniProtKB=E9H0K2	Daphnia pulex	O
DROME\|FlyBase=FBgn0033192\|UniProtKB=A1Z709	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP004571\|UniProtKB=A0A1S4GM58	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004568\|UniProtKB=A0A1S4GLF3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP008649\|UniProtKB=A0A1S4GYV4	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004570\|UniProtKB=A0A1S4GM14	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012037\|UniProtKB=Q7PZR2	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006631\|UniProtKB=A0A1S4GSR0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000250\|UniProtKB=D6WBS5	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC007026\|UniProtKB=D2A2P2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC010781\|UniProtKB=D6W7Q1	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347753\|UniProtKB=E9GLZ3	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347752\|UniProtKB=E9GLZ2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347754\|UniProtKB=E9GLZ6	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_317027\|UniProtKB=E9GEP9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW024505\|UniProtKB=B7PWZ1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002979\|UniProtKB=B7P8G5	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG178982\|UniProtKB=T1FE04	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	O