PANTHER Gene Information

Gene Symbol(s):

Kcnd2

Organism:

Rattus norvegicus

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Potassium voltage-gated channel subfamily D member 2

Gene ID:

68393

Protein ID:

Q63881

Persistent Id:

PTN000165428

Alternate Ids:

65180(GeneID)	38257805(GI)
AAB19939(EMBL-CDS)	S64320(EMBL)
68393(RGD)	CHEMBL1075227(ChEMBL)
Kcnd2(Symbol)	KCND2(Synonym)
Q99249(AltAccession)	NM_031730(refSeq)
KCND2_RAT(UniProtKB-ID)
Show All

PANTHER Classification

PANTHER Family:	VOLTAGE-GATED POTASSIUM CHANNEL (PTHR11537)
PANTHER Subfamily:	POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY D MEMBER 2 (PTHR11537:SF265)
PANTHER GO-slim Molecular Function:	voltage-gated potassium channel activity
PANTHER GO-slim Biological Process:	potassium ion transmembrane transport action potential
PANTHER GO-slim Cellular Component:	voltage-gated potassium channel complex neuronal cell body postsynaptic membrane dendritic spine
PANTHER protein class:	voltage-gated ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	monoatomic ion channel activity, voltage-gated potassium channel activity, protein binding, metal ion binding, A-type (transient outward) potassium channel activity, potassium channel activity, voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential, protein-containing complex binding
GO BP Complete:	regulation of postsynaptic membrane potential, potassium ion transmembrane transport, cardiac muscle cell action potential, protein homooligomerization, membrane repolarization, potassium ion transport, cellular response to mechanical stimulus, locomotor rhythm, muscle contraction, sensory perception of pain, action potential, cellular response to xenobiotic stimulus, cellular response to hypoxia, neuronal action potential
GO CC Complete:	voltage-gated potassium channel complex, neuronal cell body membrane, neuronal cell body, perikaryon, plasma membrane raft, Kv4.2-KChIP2 channel complex, plasma membrane, GABA-ergic synapse, T-tubule, dendrite, caveola, potassium channel complex, anchoring junction, perinuclear endoplasmic reticulum, postsynaptic membrane, sarcolemma, membrane, dendritic spine, postsynaptic specialization membrane, glutamatergic synapse

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Potassium Channels, Muscle contraction, Neuronal System, Phase 1 - inactivation of fast Na+ channels, Cardiac conduction, Voltage gated Potassium channels

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6238\|UniProtKB=Q9NZV8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000047469.1\|UniProtKB=K7BBB6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043715.1\|UniProtKB=A0A2I2YDN6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000023308.4\|UniProtKB=F7FAN1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=102663\|UniProtKB=Q9Z0V2	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000032077.4\|UniProtKB=F1MVI5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005009652.1\|UniProtKB=A0A8D1W095	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000002703.4\|UniProtKB=F6U3G2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000007877.4\|UniProtKB=M3W8J5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845006842.1\|UniProtKB=A0A8I3NFJ8	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845010446.1\|UniProtKB=A0A8I3RXY5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010033.4\|UniProtKB=F6TUH7	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000024535.3\|UniProtKB=F7F5R2	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010001419.1\|UniProtKB=E1BS72	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007207.3\|UniProtKB=G1KG88	Anolis carolinensis	LDO
XENLA\|Gene=LOC108712359\|UniProtKB=A0A8J1MSN5	Xenopus laevis	O
XENLA\|Gene=LOC108711141\|UniProtKB=A0A8J1MLP2	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000033363\|UniProtKB=A0A6I8PXE5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000021857.1\|UniProtKB=A0A3B3HRE6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004270.2\|UniProtKB=H2LH88	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041210-70\|UniProtKB=Q5VSI1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000015789.1\|UniProtKB=W5NFM9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004803.3\|UniProtKB=F6REB0	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_78444\|UniProtKB=C3Z458	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421157\|UniProtKB=A0A9J7MWK8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418913\|UniProtKB=A0A9J7MW09	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408964\|UniProtKB=A0A9J7KLS9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430021\|UniProtKB=A0A9J7NBM2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404346\|UniProtKB=A0A9J7HJN0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404602\|UniProtKB=A0A9J7HJV4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426672\|UniProtKB=A0A9J7N6T0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425700\|UniProtKB=A0A9J7LXR2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416426\|UniProtKB=A0A9J7MQW7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415127\|UniProtKB=A0A9J7L4Q9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415128\|UniProtKB=A0A9J7L3A5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425708\|UniProtKB=A0A9J7LWY6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425718\|UniProtKB=A0A9J7LWY8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415892\|UniProtKB=A0A9J7L600	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC582202\|UniProtKB=A0A7M7PTR7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022240\|UniProtKB=Q95XD1	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG05460\|UniProtKB=A8WZX5	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00106676\|UniProtKB=A0A8R1YFL8	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0005564\|UniProtKB=P17971	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007046\|UniProtKB=Q7QIS7	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004130\|UniProtKB=D6W6N1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_20278\|UniProtKB=E9GRI2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW001662\|UniProtKB=A0A1S4KNL0	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG162251\|UniProtKB=T1ESF0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG84384\|UniProtKB=T1G5I2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG72163\|UniProtKB=T1G0W6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g1485\|UniProtKB=A7RI86	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g85827\|UniProtKB=A7RLC9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g137731\|UniProtKB=A7SYB8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90372\|UniProtKB=A7RQS3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90231\|UniProtKB=A7RQS2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149024\|UniProtKB=A7T7L8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218758\|UniProtKB=A7SWW3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g1001\|UniProtKB=A7RLG2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g86018\|UniProtKB=A7RLC8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228549\|UniProtKB=A7RQS4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g135889\|UniProtKB=A7SWW6	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_8918\|UniProtKB=A9V1I5	Monosiga brevicollis	O
CRYNJ\|EnsemblGenome=CNB01080\|UniProtKB=Q5KMN4	Cryptococcus neoformans	O
PLAF7\|EnsemblGenome=PF3D7_1227200\|UniProtKB=Q8I5E6	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00032334001\|UniProtKB=A0BU85	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025187001\|UniProtKB=A0EAY6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003436001\|UniProtKB=A0E5K8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000712001\|UniProtKB=A0CJN3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000081001\|UniProtKB=Q6BFH0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00000998001\|UniProtKB=A0CKG7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009073001\|UniProtKB=A0CPG4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029282001\|UniProtKB=A0BI79	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_3601\|UniProtKB=B8BY88	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_25101\|UniProtKB=B8LCD0	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GVD0_PHYRM\|UniProtKB=H3GVD0	Phytophthora ramorum	O
PHYRM\|Gene=H3GVB5_PHYRM\|UniProtKB=H3GVB5	Phytophthora ramorum	O
PHYRM\|Gene=H3GS39_PHYRM\|UniProtKB=H3GS39	Phytophthora ramorum	O
PHYRM\|Gene=H3HCU8_PHYRM\|UniProtKB=H3HCU8	Phytophthora ramorum	O
PHYRM\|Gene=H3HCR2_PHYRM\|UniProtKB=H3HCR2	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g022150v5\|UniProtKB=A8HPX4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g432550v5\|UniProtKB=A8IB39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_11g468353v5\|UniProtKB=A0A2K3D845	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g330400v5\|UniProtKB=A0A2K3DJW6	Chlamydomonas reinhardtii	O
THEKO\|EnsemblGenome=TK1300\|UniProtKB=Q5JGQ8	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_0221\|UniProtKB=A9WC81	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO7196\|UniProtKB=Q9FBY6	Streptomyces coelicolor	O
LISMO\|Gene=Q8Y5K1_LISMO\|UniProtKB=Q8Y5K1	Listeria monocytogenes	O
DEIRA\|EnsemblGenome=DR_0830\|UniProtKB=Q9RW39	Deinococcus radiodurans	O
BACTN\|EnsemblGenome=BT_2572\|UniProtKB=Q8A4M7	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_4486\|UniProtKB=Q89Z91	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB12424\|UniProtKB=Q7UIN7	Rhodopirellula baltica	O
BRADU\|Gene=Q89CE1_BRADU\|UniProtKB=Q89CE1	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89I90_BRADU\|UniProtKB=Q89I90	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC3283\|UniProtKB=Q8P5Q3	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1496\|UniProtKB=Q9I3L6	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM1741\|UniProtKB=Q8ZP47	Salmonella typhimurium	O