PANTHER Gene Information

Gene Symbol(s):

Lhx2

Organism:

Rattus norvegicus

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Gene Name:

LIM_homeobox protein Lhx2

Gene ID:

71076

Protein ID:

P36198

Persistent Id:

PTN000654437

Alternate Ids:

L06804(EMBL)	Lhx2(Symbol)
547852(GI)	LHX2_RAT(UniProtKB-ID)
LHX2(Synonym)	71076(RGD)
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PANTHER Classification

PANTHER Family:	LIM/HOMEOBOX PROTEIN LHX (PTHR24208)
PANTHER Subfamily:	LIM_HOMEOBOX PROTEIN LHX2 (PTHR24208:SF80)
PANTHER GO-slim Molecular Function:	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	neuron differentiation regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	homeodomain transcription factor

Pathway Categories:

Gonadotropin-releasing hormone receptor pathway

LHX2

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, chromatin binding, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	negative regulation of gene expression, epigenetic, telencephalon development, telencephalon regionalization, neuron differentiation, retina development in camera-type eye, nervous system development, mesoderm development, axon guidance, anatomical structure formation involved in morphogenesis, neurogenesis, brain development, cerebral cortex development, positive regulation of transcription by RNA polymerase II, olfactory bulb development, regulation of transcription by RNA polymerase II, dorsal/ventral pattern formation, neural tube closure, hair follicle development, maintenance of epithelial cell apical/basal polarity, positive regulation of DNA-templated transcription, axon extension, positive regulation of neural precursor cell proliferation, negative regulation of neurogenesis
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6594\|UniProtKB=P50458	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021351.4\|UniProtKB=H2QXV2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008475.3\|UniProtKB=G3QZH4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003671.4\|UniProtKB=F6TBF3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96785\|UniProtKB=Q9Z0S2	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000010990.6\|UniProtKB=E1BM14	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005586.5\|UniProtKB=C4TJC6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009405.4\|UniProtKB=A0A9L0R713	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006890.6\|UniProtKB=M3W6P1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010906.1\|UniProtKB=A0A8I3RW43	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000019739.5\|UniProtKB=F6X3T3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043102.1\|UniProtKB=A0A6I8NE48	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028411.1\|UniProtKB=A0A8V1ADM2	Gallus gallus	LDO
XENLA\|Gene=lhx2.L\|UniProtKB=A0A1L8F6B6	Xenopus laevis	LDO
XENLA\|Gene=lhx2.S\|UniProtKB=Q6K1E8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-490331\|UniProtKB=A0A803K5A2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016465.2\|UniProtKB=H2MPF5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-091118-109\|UniProtKB=E9QBI8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-051220-1\|UniProtKB=B0R107	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005257.1\|UniProtKB=W5MD70	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118421290\|UniProtKB=A0A9J7LK34	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421571\|UniProtKB=A0A9J7LL10	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_68976\|UniProtKB=C3ZG21	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC576656\|UniProtKB=A0A7M7PRL6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006654\|UniProtKB=G5EE86	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00023690\|UniProtKB=A8WML0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00098361\|UniProtKB=A0A2A6C864	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0267978\|UniProtKB=P29673	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008980\|UniProtKB=A0A1S4GZT4	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP008979\|UniProtKB=A0A1S4GZR6	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_13685\|UniProtKB=E9HQZ7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_65174\|UniProtKB=E9HQZ8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW022561\|UniProtKB=A0A1S4M1H9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG73313\|UniProtKB=T1G1C8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG150188\|UniProtKB=T1EKE7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98128\|UniProtKB=A7RYP5	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG14836\|UniProtKB=B3RP90	Trichoplax adhaerens	O
NEUCR\|EnsemblGenome=NCU09556\|UniProtKB=Q7S2A5	Neurospora crassa	O