PANTHER Gene Information

Gene Symbol(s):

clp1

Organism:

Schizosaccharomyces pombe

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Gene Name:

Tyrosine-protein phosphatase CDC14 homolog

Gene ID:

SPAC1782.09c

Protein ID:

Q9P7H1

Persistent Id:

PTN000597047

Alternate Ids:

3.1.3.48(EC)	26393807(GI)
FLP1_SCHPO(UniProtKB-ID)	NP_594716(refSeq)
CDC fourteen-like phosphatase 1(Synonym)	clp1(Symbol)
CAB76271(EMBL-CDS)	SPAC1782.09c(Ensembl_TRS)
SPAC1782.09c.1:pep(Ensembl_PRO)	CU329670(EMBL)
SPAC1782.09c(Ensembl)	2542358(GeneID)
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PANTHER Classification

PANTHER Family:	TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE (PTHR23339)
PANTHER Subfamily:	PROTEIN-TYROSINE-PHOSPHATASE (PTHR23339:SF27)
PANTHER GO-slim Molecular Function:	protein tyrosine phosphatase activity
PANTHER GO-slim Biological Process:	regulation of cytokinesis microtubule cytoskeleton organization positive regulation of cell cycle process positive regulation of cell division regulation of mitotic cell cycle phase transition
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	protein phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity, protein binding, protein tyrosine phosphatase activity
GO BP Complete:	positive regulation of septation initiation signaling, regulation of exit from mitosis, protein localization to mitotic spindle pole body, microtubule cytoskeleton organization, regulation of mitotic cytokinesis, positive regulation of mitotic actomyosin contractile ring assembly, DNA damage response, positive regulation of mitotic spindle elongation, mitotic cytokinesis checkpoint signaling, positive regulation of mitotic sister chromatid biorientation, positive regulation of exit from mitosis, response to mitotic cell cycle spindle assembly checkpoint signaling, positive regulation of mitotic cytokinesis, negative regulation of G2/M transition of mitotic cell cycle, positive regulation of cytokinesis
GO CC Complete:	cell division site, mitotic actomyosin contractile ring, intermediate layer, spindle pole, mitotic actomyosin contractile ring, kinetochore, nucleolus, mitotic spindle pole body, nucleoplasm, mitotic spindle midzone, nucleus, mitotic spindle, cytoplasm, nucleolar peripheral inclusion body, spindle pole body

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Regulation of mitotic cell cycle, APC/C-mediated degradation of cell cycle proteins, Signal Transduction, Cell Cycle, Mitotic, Cell Cycle, MAPK family signaling cascades, MAPK6/MAPK4 signaling, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase

Orthologs

ID	Organism	Type
HUMAN\|HGNC=22427\|UniProtKB=A4D256	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000048690.1\|UniProtKB=A0A2I3RRW8	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000047431.1\|UniProtKB=A0A2I3T3I7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000027917.2\|UniProtKB=G3RR83	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008002.3\|UniProtKB=A0A1D5QHC5	Macaca mulatta	O
HUMAN\|HGNC=1719\|UniProtKB=O60729	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021155.7\|UniProtKB=A0A2I3SFQ6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000021155.7\|UniProtKB=A0A2I3SFQ6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008986.3\|UniProtKB=G3R0U4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005997.4\|UniProtKB=F6UDW4	Macaca mulatta	O
MOUSE\|MGI=MGI=2441808\|UniProtKB=Q6PFY9	Mus musculus	O
RAT\|RGD=1311163\|UniProtKB=A0A8I5YC46	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000011589.6\|UniProtKB=A0A3Q1N5B2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027557.4\|UniProtKB=A0A286ZK37	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000029122.3\|UniProtKB=A0A9L0TGJ8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000024293.4\|UniProtKB=A0A337SP80	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003296.1\|UniProtKB=A0A8I3MKA6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012388.3\|UniProtKB=F7BZ82	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000544.4\|UniProtKB=F6XN43	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010010844.1\|UniProtKB=A0A1D5PXT4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012788.4\|UniProtKB=A0A803T948	Anolis carolinensis	O
XENLA\|Gene=cdc14b.S\|UniProtKB=A0A8J1LMV0	Xenopus laevis	O
XENLA\|Gene=cdc14b.L\|UniProtKB=A0A8J0V493	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-977314\|UniProtKB=A4IJ03	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003939.3\|UniProtKB=A0A3B3IE46	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000009181.1\|UniProtKB=W5MS44	lepisosteus oculatus	O
HUMAN\|HGNC=1718\|UniProtKB=Q9UNH5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001007.6\|UniProtKB=K7CBN5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006770.3\|UniProtKB=A0A2I2Z2L9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000019106.4\|UniProtKB=A0A5F7ZH83	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2442676\|UniProtKB=Q6GQT0	Mus musculus	LDO
RAT\|RGD=1304649\|UniProtKB=A0A8I6B415	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031439.4\|UniProtKB=E1BLR2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006864.5\|UniProtKB=F1S565	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016838.4\|UniProtKB=A0A9L0TJN3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002505.6\|UniProtKB=A0A5F5XPU6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012548.1\|UniProtKB=A0A8I3NCU0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003521.4\|UniProtKB=A0A5F8GIY5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001831.3\|UniProtKB=A0A6I8NIE7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023710.1\|UniProtKB=A0A8V0ZW37	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003158.3\|UniProtKB=G1KBN9	Anolis carolinensis	LDO
XENLA\|Gene=cdc14a.L\|UniProtKB=Q6GLY3	Xenopus laevis	O
XENLA\|Gene=cdc14a.S\|UniProtKB=A0A1L8GGF5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-960625\|UniProtKB=F7EMN5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013619.2\|UniProtKB=H2MES1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1214\|UniProtKB=Q7SXZ4	Danio rerio	O
DANRE\|Gene=cdc14b\|UniProtKB=A0A8M2BE48	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-070705-309\|UniProtKB=A0A0R4IVA4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000000103.1\|UniProtKB=W5LVG2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007516.3\|UniProtKB=F6UJI9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118431778\|UniProtKB=A0A9J7MD02	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115918471\|UniProtKB=A0A7M7SW78	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000383\|UniProtKB=P81299	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG02450\|UniProtKB=A8WUA9	Caenorhabditis briggsae	LDO
CAEBR\|Gene_ORFName=CBG02452\|UniProtKB=A8WUA7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112238\|UniProtKB=A0A2A6B9B7	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031952\|UniProtKB=Q9VLW7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029670\|UniProtKB=A0A453Z0L5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008603\|UniProtKB=D6WTN6	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001964\|UniProtKB=A0A139WA89	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_201727\|UniProtKB=E9HA32	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000542\|UniProtKB=B7P3Q9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG188439\|UniProtKB=T1FPZ6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG91786\|UniProtKB=T1G889	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG77242\|UniProtKB=T1G2U9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210849\|UniProtKB=A7SE41	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g11161\|UniProtKB=A7SDJ9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG27920\|UniProtKB=B3S2H1	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_33516\|UniProtKB=A9V5U2	Monosiga brevicollis	LDO
YEAST\|SGD=S000001924\|UniProtKB=Q00684	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL025W\|UniProtKB=Q757N7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000180943\|UniProtKB=Q59NH8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E16038g\|UniProtKB=Q6C5Q7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05057\|UniProtKB=Q5B323	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G12250\|UniProtKB=Q4WY95	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03246\|UniProtKB=Q7SCM5	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_12669\|UniProtKB=A7F4Z4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_10769\|UniProtKB=Q0UBU5	Phaeosphaeria nodorum	LDO
SCHJY\|EnsemblGenome=SJAG_00082\|UniProtKB=B6JUY3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA04770\|UniProtKB=Q5KNZ4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06187\|UniProtKB=A0A0D1BUL5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_13987\|UniProtKB=E3KTJ1	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_22794\|UniProtKB=F4NXK9	Batrachochytrium dendrobatidis	LDO
LEIMA\|EnsemblGenome=LMJF_09_0420\|UniProtKB=Q4QHY2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.4270\|UniProtKB=Q382T8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_9270\|UniProtKB=A8BAI9	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_362610\|UniProtKB=A2E639	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_168700\|UniProtKB=A2FHE7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_458950\|UniProtKB=A2E6A0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_490830\|UniProtKB=A2E026	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_479730\|UniProtKB=A2F8F0	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00024658001\|UniProtKB=A0E9G0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00030541001\|UniProtKB=A0BMY7	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00010135001\|UniProtKB=A0CSU6	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_14971\|UniProtKB=B8LD57	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G9E5_PHYRM\|UniProtKB=H3G9E5	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G5J9_PHYRM\|UniProtKB=H3G5J9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g105400v5\|UniProtKB=A0A2K3E2J4	Chlamydomonas reinhardtii	LDO
TOBAC\|Gene=LOC107822933\|UniProtKB=A0A1S4CUV2	Nicotiana tabacum	LDO
SELML\|EnsemblGenome=SELMODRAFT_91859\|UniProtKB=D8RE91	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_3248\|UniProtKB=D8STT9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c27_7750\|UniProtKB=A0A7I4CZ80	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0079s0039\|UniProtKB=A0A2R6WKZ6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001630070\|UniProtKB=A0A1Y1I320	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1760\|UniProtKB=A9A3V6	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0177\|UniProtKB=B1L3A8	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0609\|UniProtKB=B1L4I3	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO2453\|UniProtKB=Q97VZ7	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1536\|UniProtKB=Q8ZX04	Pyrobaculum aerophilum	O
METJA\|EnsemblGenome=MJ_ECL20\|UniProtKB=Q60280	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0215\|UniProtKB=Q57668	Methanocaldococcus jannaschii	O
THEKO\|EnsemblGenome=TK0241\|UniProtKB=Q8X270	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_0153\|UniProtKB=A9WBK0	Chloroflexus aurantiacus	O
DEIRA\|EnsemblGenome=DR_2161\|UniProtKB=Q9RSG3	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NLX9_GLOVI\|UniProtKB=Q7NLX9	Gloeobacter violaceus	O
SHEON\|Gene_OrderedLocusName=SO_0090\|UniProtKB=Q8EKK2	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1070\|UniProtKB=Q9KT35	Vibrio cholerae	O