PANTHER Gene Information

Gene Symbol(s):

pfh1

Organism:

Schizosaccharomyces pombe

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Gene Name:

ATP-dependent DNA helicase pfh1

Gene ID:

SPBC887.14c

Protein ID:

Q9UUA2

Persistent Id:

PTN000588807

Alternate Ids:

SPBC887.14c(Ensembl)	19113280(GI)
CU329671(EMBL)	AAC26139(EMBL-CDS)
PIF1(Synonym)	pfh1(Symbol)
PIF1_SCHPO(UniProtKB-ID)	2541213(GeneID)
NM_001022408(refSeq)	O74239(AltAccession)
3.6.4.12 {ECO:0000255\|HAMAP-Rule:MF_03176}(EC)
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PANTHER Classification

PANTHER Family:	DNA HELICASE-RELATED (PTHR23274)
PANTHER Subfamily:	ATP-DEPENDENT DNA HELICASE PIF1 (PTHR23274:SF11)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, ATP binding, RNA binding, G-quadruplex DNA binding, flap-structured DNA binding, DNA/DNA annealing activity, ATP-dependent protein-DNA complex displacement activity, single-stranded DNA helicase activity, 5'-3' DNA/RNA helicase activity, single-stranded DNA binding, 5'-3' DNA helicase activity
GO BP Complete:	mitochondrial DNA repair, G-quadruplex DNA unwinding, mitotic recombination-dependent replication fork processing, DNA recombination, removal of RNA primer involved in mitotic DNA replication, telomere maintenance, replication fork processing, DNA strand elongation involved in mitotic DNA replication, replication fork reversal, mitochondrial genome maintenance
GO CC Complete:	nucleus, mitochondrial chromosome, site of double-strand break, mitochondrion, nuclear replication fork, rDNA heterochromatin, chromosome, telomeric repeat region, nucleolus, chromatin, nuclear replisome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=26220\|UniProtKB=Q9H611	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007166.3\|UniProtKB=K7BQX3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012347.3\|UniProtKB=G3S8K9	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=2143057\|UniProtKB=Q80SX8	Mus musculus	LDO
RAT\|RGD=1586053\|UniProtKB=Q1HG60	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007638.5\|UniProtKB=F1MMJ1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004548.5\|UniProtKB=F1S0B3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005316.4\|UniProtKB=A0A9L0R620	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000011335.6\|UniProtKB=M3WEX7	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000010476.4\|UniProtKB=F7ET02	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001139.5\|UniProtKB=F6R806	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022480.1\|UniProtKB=A0A8V0ZR10	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013162.4\|UniProtKB=G1KND2	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000008579.2\|UniProtKB=H2LXB4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4928\|UniProtKB=Q7ZV90	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004184.1\|UniProtKB=W5M9F7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002828.3\|UniProtKB=F6WYU9	Ciona intestinalis	LDO
CAEEL\|WormBase=WBGene00008695\|UniProtKB=O02243	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00004028\|UniProtKB=G5EFV7	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029368\|UniProtKB=A8X541	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00027672\|UniProtKB=A8WZ54	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00203407\|UniProtKB=A0A8R1YLI9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0031540\|UniProtKB=Q9VQR3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007775\|UniProtKB=Q7Q395	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_118315\|UniProtKB=E9HVD9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_338047\|UniProtKB=E9I2G8	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_247612\|UniProtKB=E9GST4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_253307\|UniProtKB=E9H4I9	Daphnia pulex	LDO
YEAST\|SGD=S000001073\|UniProtKB=P38766	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER233C\|UniProtKB=Q756M1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000174602\|UniProtKB=A0A1D8PRM6	Candida albicans	LDO
YEAST\|SGD=S000004526\|UniProtKB=P07271	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AER128W\|UniProtKB=Q756Y6	Eremothecium gossypii	O
CANAL\|CGD=CAL0000185430\|UniProtKB=Q59RQ0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_A03927g\|UniProtKB=Q6CHW9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D02607g\|UniProtKB=Q6CAI0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D09669g\|UniProtKB=Q6C9N7	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A11539g\|UniProtKB=Q6CH79	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_B12892g\|UniProtKB=Q6CEU3	Yarrowia lipolytica	LDO
EMENI\|Gene_ORFName=AN6895\|UniProtKB=Q5AXT5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G13370\|UniProtKB=Q4WVU7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07519\|UniProtKB=U9W8Y3	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_00870\|UniProtKB=Q0V544	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU00428\|UniProtKB=Q7RXT1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07493\|UniProtKB=A7EQ93	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_03340\|UniProtKB=A7EDF0	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_10457\|UniProtKB=Q0UCQ7	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNC04645\|UniProtKB=A0A0S2LIE3	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNH02480\|UniProtKB=Q5KCW7	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC02830\|UniProtKB=Q5KKJ1	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02718\|UniProtKB=A0A0D1DZD7	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_06292\|UniProtKB=E3K7N8	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_19486\|UniProtKB=E3LA34	Puccinia graminis	LDO
ENTH1\|EnsemblGenome=CL6EHI_014050\|UniProtKB=C4LXP4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_192830\|UniProtKB=C4M921	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0293212\|UniProtKB=Q54C21	Dictyostelium discoideum	LDO
DICDI\|dictyBase=DDB_G0277925\|UniProtKB=Q54Z42	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0268430\|UniProtKB=Q55FJ4	Dictyostelium discoideum	O
LEIMA\|EnsemblGenome=LMJF_11_0320\|UniProtKB=Q4QH48	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.02.4740\|UniProtKB=Q384Y0	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_11_0330\|UniProtKB=Q4QH47	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.6420\|UniProtKB=Q381V6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb11.02.4730\|UniProtKB=Q384Y1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_21_1190\|UniProtKB=Q4QC77	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.7240\|UniProtKB=Q38CE9	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_28_2530\|UniProtKB=Q4Q810	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.3660\|UniProtKB=Q383A1	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_07_1020\|UniProtKB=Q4QII5	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.8.3560\|UniProtKB=Q580X6	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.8.700\|UniProtKB=Q57YG0	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_16747\|UniProtKB=A8BBU9	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_172600\|UniProtKB=A2DF11	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_352730\|UniProtKB=A2EG75	Trichomonas vaginalis	O
PHYRM\|Gene=H3GS12_PHYRM\|UniProtKB=H3GS12	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g551550v5\|UniProtKB=A0A2K3D646	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g296150v5\|UniProtKB=A0A2K3DQP7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g485438v5\|UniProtKB=A0A2K3D1R3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g685613v5\|UniProtKB=A0A2K3CW35	Chlamydomonas reinhardtii	LDO
NELNU\|Gene_ORFName=HUJ06_026511\|UniProtKB=A0A1U8BEI6	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_026512\|UniProtKB=A0A1U8B2Z3	Nelumbo nucifera	LDO
CAPAN\|EnsemblGenome=T459_23767\|UniProtKB=A0A2G2YTB6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_20386\|UniProtKB=A0A2G2Z4J0	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017364\|UniProtKB=M1BGL4	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc07g055900.1\|UniProtKB=A0A3Q7HDF5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107825343\|UniProtKB=A0A1S4D2R7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107787401\|UniProtKB=A0A1S3ZIZ9	Nicotiana tabacum	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K01193\|UniProtKB=A0A059A130	Eucalyptus grandis	LDO
THECC\|EnsemblGenome=TCM_001831\|UniProtKB=A0A061DJT2	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_007G054500v3\|UniProtKB=U5G804	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G085900\|UniProtKB=A0A2C9WC44	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1195020\|UniProtKB=B9S328	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G310900\|UniProtKB=K7LA09	Glycine max	LDO
JUGRE\|EnsemblGenome=Jr10_13650\|UniProtKB=A0A2I4EYT3	Juglans regia	LDO
PRUPE\|EnsemblGenome=PRUPE_3G170200\|UniProtKB=A0A251Q1C1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_451566\|UniProtKB=D8SVL5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_451567\|UniProtKB=D8RVZ3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c19_4830\|UniProtKB=A0A2K1IX83	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_2590\|UniProtKB=A0A2K1ITR8	Physcomitrella patens	LDO
BACTN\|EnsemblGenome=BT_0721\|UniProtKB=Q8A9U4	Bacteroides thetaiotaomicron	LDO
BACTN\|EnsemblGenome=BT_4130\|UniProtKB=Q8A091	Bacteroides thetaiotaomicron	O
THEYD\|EnsemblGenome=THEYE_A0975\|UniProtKB=B5YKP3	Thermodesulfovibrio yellowstonii	LDO
GEOSL\|EnsemblGenome=GSU0763\|UniProtKB=Q74F46	Geobacter sulfurreducens	LDO