PANTHER Gene Information

Gene Symbol(s):

101761852

Organism:

Setaria italica

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Tree

Gene Name:

Malate dehydrogenase

Gene ID:

SETIT_022252mg

Protein ID:

K3Z6T3

Persistent Id:

PTN004268470

Alternate Ids:

AGNK02001801(EMBL)	XM_004962326(refSeq)
514751605(GI)	K3Z6T3(Synonym)
SETIT_022252mg(Ensembl)	K3Z6T3_SETIT(UniProtKB-ID)
101761852(GeneID)	RCV18134(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	MALATE AND LACTATE DEHYDROGENASE (PTHR11540)
PANTHER Subfamily:	MALATE DEHYDROGENASE, MITOCHONDRIAL (PTHR11540:SF16)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	dehydrogenase

Pathway Categories:

Pyruvate metabolism

Lactate Dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-malate dehydrogenase (NAD+) activity, oxidoreductase activity
GO BP Complete:	malate metabolic process, tricarboxylic acid cycle
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6971\|UniProtKB=P40926	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000019316.4\|UniProtKB=H2QUS9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011790.3\|UniProtKB=G3R803	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009917.4\|UniProtKB=G7MNY8	Macaca mulatta	O
MOUSE\|MGI=MGI=97050\|UniProtKB=P08249	Mus musculus	O
RAT\|RGD=619719\|UniProtKB=P04636	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009462\|UniProtKB=Q32LG3	Bos taurus	O
PIG\|Gene=MDH2\|UniProtKB=P00346	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000025486.4\|UniProtKB=A0A480KJB8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000023094.3\|UniProtKB=F6TYW4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000600\|UniProtKB=K0J107	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023313.1\|UniProtKB=A0A8I3S3J3	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845021959.1\|UniProtKB=A0A8I3S5A9	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845024163.1\|UniProtKB=A0A8I3PHB7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845019601.1\|UniProtKB=A0A8I3MS45	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000013680.3\|UniProtKB=F6QQ58	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001378.4\|UniProtKB=F7EM18	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010029614.1\|UniProtKB=E1BVT3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001457.4\|UniProtKB=H9G589	Anolis carolinensis	O
XENLA\|Gene=mdh2.S\|UniProtKB=Q6GR58	Xenopus laevis	O
XENLA\|Gene=mdh2.L\|UniProtKB=Q6B4U5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-971714\|UniProtKB=F6T7F0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005748.2\|UniProtKB=H2LMF5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-2143\|UniProtKB=Q7T334	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001699.1\|UniProtKB=W5M0R3	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008796.3\|UniProtKB=F6SCN2	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_114460\|UniProtKB=C3Z482	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115926793\|UniProtKB=A0A7M7PEH1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587163\|UniProtKB=A0A7M7RDC7	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003162\|UniProtKB=O02640	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035534\|UniProtKB=A8XLN4	Caenorhabditis briggsae	O
DROME\|FlyBase=FBgn0036328\|UniProtKB=Q9VU29	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036327\|UniProtKB=Q9VU28	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0262559\|UniProtKB=Q9VEB1	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001903\|UniProtKB=Q7PYE7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007643\|UniProtKB=D2A2I7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC012844\|UniProtKB=D6X178	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC005504\|UniProtKB=D6WXV9	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC015050\|UniProtKB=D2A663	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_301215\|UniProtKB=E9HGX0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003528\|UniProtKB=B7PH44	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG185773\|UniProtKB=T1FN98	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG104724\|UniProtKB=T1EDN4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215948\|UniProtKB=A7SQS1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g248519\|UniProtKB=A7T1J0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG34967\|UniProtKB=B3SFB4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_38523\|UniProtKB=A9V8G5	Monosiga brevicollis	O
YEAST\|SGD=S000005486\|UniProtKB=P22133	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADL164C\|UniProtKB=Q75AT4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000184598\|UniProtKB=Q5A5S6	Candida albicans	O
CANAL\|CGD=CAL0000181993\|UniProtKB=P83778	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E14190g\|UniProtKB=Q6C5X9	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05031\|UniProtKB=Q5B349	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_06499\|UniProtKB=C8V0H6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G05210\|UniProtKB=Q4WDM0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06211\|UniProtKB=U9WGI5	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_08975\|UniProtKB=A7EUG8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09027\|UniProtKB=Q0UGT7	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNG03100\|UniProtKB=Q5KDR0	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_11161\|UniProtKB=A0A0D1BZ90	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_04865\|UniProtKB=E3K352	Puccinia graminis	O
YEAST\|SGD=S000002236\|UniProtKB=P32419	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR252W\|UniProtKB=Q759M4	Eremothecium gossypii	O
YEAST\|SGD=S000001568\|UniProtKB=P17505	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR152C\|UniProtKB=Q759X1	Eremothecium gossypii	O
CANAL\|CGD=CAL0000181799\|UniProtKB=Q5AMP4	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D16753g\|UniProtKB=Q6C8V3	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06717\|UniProtKB=C8V1V3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_7G05740\|UniProtKB=Q4WGP3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU04899\|UniProtKB=Q7S1D6	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_13825\|UniProtKB=A7F894	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_05974\|UniProtKB=Q0UQJ0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPCC306.08c\|UniProtKB=Q9Y7R8	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01753\|UniProtKB=B6JYT4	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNG03490\|UniProtKB=Q5KDL9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00403\|UniProtKB=A0A0D1CG83	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_17218\|UniProtKB=E3L321	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_17222\|UniProtKB=F4P7E9	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_13896\|UniProtKB=F4PAW7	Batrachochytrium dendrobatidis	O
LEIMA\|EnsemblGenome=LMJF_19_0710\|UniProtKB=Q4QDF0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.61.0980\|UniProtKB=Q387X2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_34_0130\|UniProtKB=Q4Q3J5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.5120\|UniProtKB=Q38BZ0	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_34_0150\|UniProtKB=Q4Q3J3	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_34_0160\|UniProtKB=Q4Q3J2	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_34_0140\|UniProtKB=Q4Q3J4	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.5110\|UniProtKB=Q38BY9	Trypanosoma brucei	O
PLAF7\|EnsemblGenome=PF3D7_0618500\|UniProtKB=C6KT25	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1325200\|UniProtKB=Q8IE66	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1324900\|UniProtKB=Q76NM3	Plasmodium falciparum	O
THAPS\|EnsemblGenome=THAPSDRAFT_20726\|UniProtKB=B8BQC2	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GAF9_PHYRM\|UniProtKB=H3GAF9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_03g194850v5\|UniProtKB=P93106	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00025p00227200\|UniProtKB=W1PXC6	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00010p00262600\|UniProtKB=W1NG77	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_149G00220\|UniProtKB=A0A0K9PWM7	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g25700\|UniProtKB=A0A804J8J2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g04330\|UniProtKB=A0A804JCI7	Musa acuminata subsp. malaccensis	O
SORBI\|EnsemblGenome=SORBI_3007G137600\|UniProtKB=A0A1Z5R9Q9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb041400\|UniProtKB=B4FG53	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb179730\|UniProtKB=B4FFV3	Zea mays	O
ORYSJ\|EnsemblGenome=Os01g0829800\|UniProtKB=Q5QLS8	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os08g0434300\|UniProtKB=Q0J5H3	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g02920v3\|UniProtKB=A0A0Q3EEA9	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_3g37140v3\|UniProtKB=I1I7H2	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0721800\|UniProtKB=A0A8I6YEP1	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G289400\|UniProtKB=A0A3B6SJ79	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G386600\|UniProtKB=A0A3B6RJT2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G383100\|UniProtKB=A0A3B6TNQ3	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0082380\|UniProtKB=M0Z6C2	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1A02G348500\|UniProtKB=A0A3B5Y542	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G351500\|UniProtKB=A0A3B5ZZP1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G363100\|UniProtKB=A0A3B5Z2I2	Triticum aestivum	O
NELNU\|Gene=LOC104610142\|UniProtKB=A0A1U8B2I0	Nelumbo nucifera	O
SPIOL\|Gene=LOC110799436\|UniProtKB=A0A9R0J4L2	Spinacia oleracea	O
SPIOL\|Gene=LOC110778437\|UniProtKB=A0A9R0HZE7	Spinacia oleracea	O
HELAN\|Gene_ORFName=HanXRQr2_Chr02g0062351\|UniProtKB=A0A9K3P0V1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400199860\|UniProtKB=A0A9R1XIA2	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C900472560\|UniProtKB=A0A9R1UDY5	Lactuca sativa	O
HELAN\|Gene_ORFName=HanXRQr2_Chr09g0408921\|UniProtKB=A0A9K3I9W5	Helianthus annuus	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a006525mg\|UniProtKB=A0A022QAV0	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a007296mg\|UniProtKB=A0A022R7W7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_10458\|UniProtKB=A0A1U8G5G0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400019511\|UniProtKB=M1BPZ5	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g115990.2\|UniProtKB=A0A3Q7GH43	Solanum lycopersicum	O
TOBAC\|Gene=LOC107783258\|UniProtKB=A0A1S3Z5T7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107821463\|UniProtKB=A0A1S4CQ52	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi17g00607\|UniProtKB=F6GT74	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K02475\|UniProtKB=A0A059A667	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C03P71710.1\|UniProtKB=A0A078IB61	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A06P20100.1\|UniProtKB=A0A078J8R8	Brassica napus	O
BRACM\|EnsemblGenome=Bra018137\|UniProtKB=M4DNQ0	Brassica campestris	O
ARATH\|TAIR=locus=2079177\|UniProtKB=Q9SN86	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107912129\|UniProtKB=A0A1U8K3X3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107926717\|UniProtKB=A0A1U8LEV5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107953505\|UniProtKB=A0A1U8NZE2	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_014018\|UniProtKB=A0A061G4A3	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g015131mg\|UniProtKB=A0A067ENV0	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_017G101900v3\|UniProtKB=A0A2K1X5Y8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G112800v3\|UniProtKB=B9N7N3	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_017G102000v3\|UniProtKB=A0A2K1X5Z6	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_14G078500\|UniProtKB=A0A2C9UJZ5	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_06G091900\|UniProtKB=A0A2C9VPC3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1471880\|UniProtKB=B9RLY1	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_17G100600\|UniProtKB=C6TGD9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G026300\|UniProtKB=I1JZP0	Glycine max	O
JUGRE\|Gene=LOC108995464\|UniProtKB=A0A2I4F4L8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_1G009760\|UniProtKB=A0A0A0LSB1	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_7G394650\|UniProtKB=A0A0A0KAR9	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G194400\|UniProtKB=A0A251Q2N0	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_5G194200\|UniProtKB=M5W9G3	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_133026\|UniProtKB=D8T6I0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_133168\|UniProtKB=D8T6P0	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c14_9020\|UniProtKB=A0A2K1JH02	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_6520\|UniProtKB=A0A2K1J2Y5	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0068s0019\|UniProtKB=A0A2R6WPM7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001330100\|UniProtKB=A0A0U9HJR8	Klebsormidium nitens	O
PYRAE\|EnsemblGenome=PAE2370\|UniProtKB=Q8ZVB2	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_0819\|UniProtKB=Q8TSH7	Methanosarcina acetivorans	O
CHLAA\|EnsemblGenome=Caur_0900\|UniProtKB=P80040	Chloroflexus aurantiacus	O
BACSU\|EnsemblGenome=BSU_29120\|UniProtKB=P49814	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4592\|UniProtKB=Q817F9	Bacillus cereus	O
GLOVI\|EnsemblGenome=BAC90483\|UniProtKB=Q7NHJ3	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA10470\|UniProtKB=Q55383	Synechocystis	O
BACTN\|EnsemblGenome=BT_3911\|UniProtKB=Q8A0W0	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB7652\|UniProtKB=Q7UNC6	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1665\|UniProtKB=O67581	Aquifex aeolicus	O
AQUAE\|EnsemblGenome=aq_1782\|UniProtKB=O67655	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1587\|UniProtKB=B5YGI4	Thermodesulfovibrio yellowstonii	O
GEOSL\|EnsemblGenome=GSU1466\|UniProtKB=Q74D53	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC45721\|UniProtKB=Q89X59	Bradyrhizobium diazoefficiens	O