PANTHER Gene Information

Gene Symbol(s):

rnhC

Organism:

Streptococcus pneumoniae

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Gene Name:

Ribonuclease HIII

Gene ID:

spr0365

Protein ID:

P59660

Persistent Id:

PTN001658641

Alternate Ids:

RNH3_STRR6(UniProtKB-ID)	15457925(GI)
3.1.26.4(EC)	WP_000146861(refSeq)
AAK99169(EMBL-CDS)	spr0365(Ensembl)
AAK99169(Ensembl_TRS)	AE007317(EMBL)
RNase HIII(Synonym)	rnhC(Symbol)
66805595(GeneID)	AAK99169(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	RIBONUCLEASE H2 SUBUNIT A (PTHR10954)
PANTHER Subfamily:	RIBONUCLEASE (PTHR10954:SF23)
PANTHER GO-slim Molecular Function:	RNA endonuclease activity
PANTHER GO-slim Biological Process:	DNA replication mismatch repair RNA catabolic process
PANTHER GO-slim Cellular Component:	catalytic complex intracellular protein-containing complex
PANTHER protein class:	endoribonuclease

Pathway Categories:

DNA replication

RNase H

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, RNA-DNA hybrid ribonuclease activity, RNA binding, metal ion binding, endonuclease activity
GO BP Complete:	RNA metabolic process, mismatch repair, DNA replication, removal of RNA primer, RNA catabolic process
GO CC Complete:	cytoplasm, ribonuclease H2 complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18518\|UniProtKB=O75792	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010542.4\|UniProtKB=H2QFH0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005846.3\|UniProtKB=G3QSS9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000045010.2\|UniProtKB=F6U5A6	Macaca mulatta	O
MOUSE\|MGI=MGI=1916974\|UniProtKB=Q9CWY8	Mus musculus	O
RAT\|RGD=1307248\|UniProtKB=Q5U209	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000009661\|UniProtKB=Q2TBT5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005032933.1\|UniProtKB=F1SDX8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007013.3\|UniProtKB=A0A9L0RYB3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000000474.5\|UniProtKB=M3VUU3	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015846.1\|UniProtKB=A0A8I3P1A1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006997.4\|UniProtKB=F6XVJ9	Monodelphis domestica	O
ANOCA\|Ensembl=ENSACAG00000003338.4\|UniProtKB=H9G7E1	Anolis carolinensis	O
XENLA\|Gene=rnaseh2a.L\|UniProtKB=Q4FZN2	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-945840\|UniProtKB=Q6P7L6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004042.2\|UniProtKB=H2LGF8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040426-976\|UniProtKB=Q6IQM9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007890.1\|UniProtKB=W5MMH3	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006190.3\|UniProtKB=F7B1W3	Ciona intestinalis	O
BRAFL\|Gene=LOC118414461\|UniProtKB=A0A9J7L1F4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC763203\|UniProtKB=A0A7M7G456	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004383\|UniProtKB=Q9U6P6	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00027367\|UniProtKB=A8WYE0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00304301\|UniProtKB=A0A8R1Z2J5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0031252\|UniProtKB=Q9VPP5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007741\|UniProtKB=A0A1S4GW38	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC011359\|UniProtKB=D6X470	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_230884\|UniProtKB=E9GHZ3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW001993\|UniProtKB=B7PAV9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG73260\|UniProtKB=T1G1C2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210941\|UniProtKB=A7SEB2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG51212\|UniProtKB=B3SDM2	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25972\|UniProtKB=A9V104	Monosiga brevicollis	O
YEAST\|SGD=S000005016\|UniProtKB=P53942	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AER363W\|UniProtKB=Q756A4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000175451\|UniProtKB=Q5AGX6	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_D23661g\|UniProtKB=Q6C813	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_05114\|UniProtKB=Q5B2W6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G07600\|UniProtKB=Q4WJ14	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09608\|UniProtKB=Q9P5X8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01636\|UniProtKB=A7E8K8	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01231\|UniProtKB=Q0V433	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC4G9.02\|UniProtKB=Q10236	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02039\|UniProtKB=B6JZJ9	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNI02520\|UniProtKB=Q5KBH4	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_06131\|UniProtKB=A0A0D1DQ00	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_16050\|UniProtKB=E3L1N8	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_10935\|UniProtKB=E3KMX0	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_8789\|UniProtKB=F4NV99	Batrachochytrium dendrobatidis	O
ENTH1\|Gene_ORFName=EHI_134360\|UniProtKB=B1N370	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_084700\|UniProtKB=C4M1K1	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0292584\|UniProtKB=Q54D13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_26608\|UniProtKB=F0Z8W3	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_0640\|UniProtKB=Q8ISS8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.2140\|UniProtKB=Q38B94	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_6483\|UniProtKB=A8B5I7	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_262310\|UniProtKB=A2DUE3	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0623900\|UniProtKB=C6KT75	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00029875001\|UniProtKB=A0BL27	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029234001\|UniProtKB=A0BI31	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_17008\|UniProtKB=B8C1R2	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GW85_PHYRM\|UniProtKB=H3GW85	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_17g701350v5\|UniProtKB=A0A2K3CNY2	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00040p00093940\|UniProtKB=W1PSK0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_89G00230\|UniProtKB=A0A0K9NKD4	Zostera marina	O
MUSAM\|EnsemblGenome=Ma02_g02890\|UniProtKB=A0A804HYN3	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_010697mg\|UniProtKB=K3Y905	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G040300\|UniProtKB=C5YS45	Sorghum bicolor	O
SETIT\|EnsemblGenome=SETIT_012525mg\|UniProtKB=K3YE64	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G241600\|UniProtKB=C5Z8P5	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb406890\|UniProtKB=K7UBU5	Zea mays	O
ORYSJ\|EnsemblGenome=Os11g0153900\|UniProtKB=Q53QG3	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g42210v3\|UniProtKB=I1IU91	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0460390\|UniProtKB=A0A8I6YQF0	Hordeum vulgare subsp. vulgare	O
NELNU\|Gene=LOC104589003\|UniProtKB=A0A1U7YY08	Nelumbo nucifera	O
SPIOL\|Gene=LOC110790891\|UniProtKB=A0A9R0IL43	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0660611\|UniProtKB=A0A251TBD0	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200088800\|UniProtKB=A0A9R1WFI8	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a010913mg\|UniProtKB=A0A022RE79	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_29720\|UniProtKB=A0A2G2Y6A8	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400023970\|UniProtKB=M1C7Q6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc11g006860.2\|UniProtKB=A0A3Q7IPB9	Solanum lycopersicum	O
TOBAC\|Gene=LOC107791603\|UniProtKB=A0A1S3ZXU9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107771872\|UniProtKB=A0A1S3Y3T9	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi13g00975\|UniProtKB=F6HPY3	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_G02689\|UniProtKB=A0A059BHP0	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C04P55060.1\|UniProtKB=A0A078J1G4	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00080473001\|UniProtKB=A0A078JTV6	Brassica napus	O
BRACM\|EnsemblGenome=Bra032040\|UniProtKB=M4ETB0	Brassica campestris	O
ARATH\|TAIR=locus=2040189\|UniProtKB=Q9SEZ6	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107904365\|UniProtKB=A0A1U8J799	Gossypium hirsutum	O
GOSHI\|Gene=LOC107904187\|UniProtKB=A0A1U8J6K6	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_044005\|UniProtKB=A0A061FQ66	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g022427mg\|UniProtKB=A0A067DS68	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_010G239600v3\|UniProtKB=A0A2K1YZD8	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G019800v3\|UniProtKB=B9HKP4	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_10G062100\|UniProtKB=A0A2C9V3M9	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1539780\|UniProtKB=B9RPT7	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_20G111500\|UniProtKB=I1NFE4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G278500\|UniProtKB=I1LF08	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g111980\|UniProtKB=A0A072W210	Medicago truncatula	O
JUGRE\|Gene=LOC109002154\|UniProtKB=A0A6P9EFB5	Juglans regia	O
JUGRE\|EnsemblGenome=Jr14_04870\|UniProtKB=A0A2I4E2R8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G015800\|UniProtKB=A0A0A0KTZ4	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_2G069600\|UniProtKB=M5X1Z0	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_233940\|UniProtKB=D8SFY2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_439531\|UniProtKB=D8R5Q9	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c13_7860\|UniProtKB=A0A2K1JL69	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0006s0052\|UniProtKB=A0A2R6XPH6	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003340010\|UniProtKB=A0A1Y1IEK7	Klebsormidium nitens	O
DICDI\|dictyBase=DDB_G0277705\|UniProtKB=Q54ZA4	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_11524\|UniProtKB=F0ZWY3	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_36_0330\|UniProtKB=Q8WSZ0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.2470\|UniProtKB=Q38BC8	Trypanosoma brucei	LDO
LEIMA\|EnsemblGenome=LMJF_13_0050\|UniProtKB=Q4QGE9	Leishmania major	O
THAPS\|EnsemblGenome=THAPSDRAFT_7542\|UniProtKB=B8C6T8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_18530\|UniProtKB=B8C0U6	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G7Z9_PHYRM\|UniProtKB=H3G7Z9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_13g561900v5\|UniProtKB=A0A2K3CYZ5	Chlamydomonas reinhardtii	LDO
SELML\|EnsemblGenome=SELMODRAFT_450428\|UniProtKB=D8RCY3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_19600\|UniProtKB=A0A2K1L292	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0023s0164\|UniProtKB=A0A2R6XCN5	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001830070\|UniProtKB=A0A1Y1I4C1	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1393\|UniProtKB=A9A3M7	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_1147\|UniProtKB=B1L614	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0703\|UniProtKB=B1L4S5	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_0350\|UniProtKB=B1L3S7	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO2384\|UniProtKB=Q97W56	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1216\|UniProtKB=Q8ZXL6	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_1959\|UniProtKB=Q8TPF4	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0135\|UniProtKB=Q57599	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_1984G\|UniProtKB=Q9HNR3	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0805\|UniProtKB=O74035	Thermococcus kodakaraensis	LDO
MYCGE\|Gene_OrderedLocusName=MG199\|UniProtKB=P47441	mycoplasma genitalium	LDO
STAA8\|EnsemblGenome=SAOUHSC_01095\|UniProtKB=Q2FZD7	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99306\|UniProtKB=Q8Y7P5	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_28620\|UniProtKB=P94541	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4556\|UniProtKB=Q817J0	Bacillus cereus	LDO
CHLTR\|EnsemblGenome=CT_008\|UniProtKB=O84011	Chlamydia trachomatis	LDO