PANTHER Gene Information

Gene Symbol(s):

Tb07.25D22.110

Organism:

Trypanosoma brucei

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Gene Name:

Trans-sialidase

Gene ID:

Tb927.7.6850

Protein ID:

Q57XJ2

Persistent Id:

PTN002239687

Alternate Ids:

Q57XJ2(Synonym)	3658905(GeneID)
AAX69677(EMBL-CDS)	CP000070(EMBL)
72392022(GI)	XM_841212(refSeq)
Q57XJ2_TRYB2(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	SIALIDASE (PTHR10628)
PANTHER Subfamily:	EXO-ALPHA-SIALIDASE (PTHR10628:SF30)
PANTHER GO-slim Molecular Function:	hydrolase activity, hydrolyzing O-glycosyl compounds
PANTHER GO-slim Biological Process:	carbohydrate derivative catabolic process ceramide metabolic process sphingolipid catabolic process glycolipid metabolic process carbohydrate catabolic process
PANTHER GO-slim Cellular Component:	cytoplasm intracellular membrane-bounded organelle membrane
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	exo-alpha-sialidase activity, sialyltransferase activity
GO BP Complete:	sialic acid transport, oligosaccharide catabolic process, ganglioside catabolic process
GO CC Complete:	cytoplasm, intracellular membrane-bounded organelle, membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7758\|UniProtKB=Q99519	Homo sapiens	O
MACMU\|Ensembl=ENSMMUG00000021707.4\|UniProtKB=F7EZS0	Macaca mulatta	O
MOUSE\|MGI=MGI=97305\|UniProtKB=O35657	Mus musculus	O
RAT\|RGD=3163\|UniProtKB=Q99PW3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000005674\|UniProtKB=A6BMK7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000001418.5\|UniProtKB=F1RQX3	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00070023485\|UniProtKB=A5PF10	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000024446.4\|UniProtKB=M3X3Z7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013021.1\|UniProtKB=A0A8I3NN43	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000050558.1\|UniProtKB=A0A6I8NGP9	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000012147.3\|UniProtKB=G1KLY3	Anolis carolinensis	O
XENLA\|Gene=neu1.L\|UniProtKB=A0A1L8F8G4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-959028\|UniProtKB=F6WK48	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000002057.2\|UniProtKB=H2L9M4	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060503-592\|UniProtKB=Q1LWP9	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007818.1\|UniProtKB=W5MM81	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_86823\|UniProtKB=C3Y2L4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421330\|UniProtKB=A0A9J7LK79	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419529\|UniProtKB=A0A9J7MWY5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421338\|UniProtKB=A0A9J7LLR0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421704\|UniProtKB=A0A9J7LLH2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421326\|UniProtKB=K0Q6T4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421322\|UniProtKB=A0A9J7LKG3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421323\|UniProtKB=A0A9J7LMG4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421335\|UniProtKB=A0A9J7LME1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421792\|UniProtKB=A0A9J7LNT0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421327\|UniProtKB=A0A9J7MZF3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421329\|UniProtKB=K0Q1U9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421341\|UniProtKB=A0A9J7LME8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421310\|UniProtKB=A0A9J7MWT1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421333\|UniProtKB=A0A9J7LKH2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421700\|UniProtKB=A0A9J7LLH7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100890176\|UniProtKB=A0A7M7NLG3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890097\|UniProtKB=A0A7M7GG24	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446099\|UniProtKB=A0A7M7NNL4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890017\|UniProtKB=A0A7M7NL73	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115922781\|UniProtKB=A0A7M7NR48	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585449\|UniProtKB=A0A7M7RFJ3	Strongylocentrotus purpuratus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g210903\|UniProtKB=A7SE79	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_22854\|UniProtKB=A9US97	Monosiga brevicollis	O
HUMAN\|HGNC=7760\|UniProtKB=Q9UQ49	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043132.1\|UniProtKB=K7BTR7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014507.3\|UniProtKB=G3REZ7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000010686.4\|UniProtKB=A0A1D5QH49	Macaca mulatta	O
MOUSE\|MGI=MGI=1355305\|UniProtKB=Q9JMH7	Mus musculus	O
RAT\|RGD=619881\|UniProtKB=Q99PW5	Rattus norvegicus	O
BOVIN\|Gene=NEU3\|UniProtKB=O97859	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000025931.4\|UniProtKB=F1MRJ3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000021638.4\|UniProtKB=A0A286ZR19	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006601.3\|UniProtKB=F7ADI2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000033977.3\|UniProtKB=A0A2I2UWF4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006035.1\|UniProtKB=A0A8I3MQZ3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000039572.1\|UniProtKB=A0A5F8H7G2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000039167.1\|UniProtKB=A0A6I8P0B1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010001886.1\|UniProtKB=A0A8V0X3Z6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000037556.1\|UniProtKB=A0A803T8N9	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000023263.2\|UniProtKB=H9GT35	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000025561.3\|UniProtKB=H9GQ66	Anolis carolinensis	O
XENLA\|Gene=neu3.3.L\|UniProtKB=A0A1L8HJW7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-22061928\|UniProtKB=A0A1B8Y474	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-6049935\|UniProtKB=F6V078	Xenopus tropicalis	O
XENLA\|Gene=neu3.1.S\|UniProtKB=A0A8J1MHM1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-996645\|UniProtKB=K0PUS8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000809.2\|UniProtKB=G3XKV7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000028485.1\|UniProtKB=G3XKV6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071220-2\|UniProtKB=A0A0R4IGG5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-071220-1\|UniProtKB=A0A2R8QGI8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-061103-511\|UniProtKB=A0JMM3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040801-262\|UniProtKB=Q4V9A4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-061201-39\|UniProtKB=I3ITP7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002179.1\|UniProtKB=W5M2E5	lepisosteus oculatus	O
HUMAN\|HGNC=7759\|UniProtKB=Q9Y3R4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000013049.3\|UniProtKB=H2QJM5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005494.3\|UniProtKB=G3QRW5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001651.3\|UniProtKB=F7G6S2	Macaca mulatta	O
MOUSE\|MGI=MGI=1344417\|UniProtKB=Q9JMH3	Mus musculus	O
RAT\|RGD=3164\|UniProtKB=Q64627	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020672.6\|UniProtKB=G5E5Q1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016297.3\|UniProtKB=F1SM45	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000030943.3\|UniProtKB=A0A9L0TJJ4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000038619.3\|UniProtKB=A0A2I2V0G9	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020896.1\|UniProtKB=A0A8I3PBB8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000010460.3\|UniProtKB=F7F7Q7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007781.4\|UniProtKB=A0A6I8NMD8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022942.1\|UniProtKB=A0A8V0ZQN0	Gallus gallus	O
HUMAN\|HGNC=21328\|UniProtKB=Q8WWR8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000052792.1\|UniProtKB=A0A2I3T7L0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000014302.3\|UniProtKB=G3REG3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000014405.4\|UniProtKB=A0A5F7ZYG2	Macaca mulatta	O
MOUSE\|MGI=MGI=2661364\|UniProtKB=Q8BZL1	Mus musculus	O
RAT\|RGD=1308624\|UniProtKB=D3ZWB7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000014833.6\|UniProtKB=E1BMN0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000037090.3\|UniProtKB=A0A287BP79	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021892.3\|UniProtKB=F6WZS4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004992.5\|UniProtKB=M3W397	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024166.1\|UniProtKB=A0A8I3PGV9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000037347.1\|UniProtKB=A0A5F8HF43	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000000861.4\|UniProtKB=F6XNF7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010024860.1\|UniProtKB=A0A8V1A0C4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000446.3\|UniProtKB=G1K8I1	Anolis carolinensis	O
XENLA\|Gene=neu4.S\|UniProtKB=A0A8J0VAY4	Xenopus laevis	O
XENLA\|Gene=neu4.L\|UniProtKB=A0A1L8GBQ4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-959717\|UniProtKB=K0PUT3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006455.2\|UniProtKB=H2LPW5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050522-125\|UniProtKB=Q503Z4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009785.1\|UniProtKB=W5MU88	lepisosteus oculatus	O
BRAFL\|Gene=LOC118406890\|UniProtKB=A0A9J7HP14	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583431\|UniProtKB=A0A7M7P356	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890472\|UniProtKB=A0A7M7P461	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115924908\|UniProtKB=A0A7M7NZ87	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764416\|UniProtKB=A0A7M7NZA6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755390\|UniProtKB=A0A7M7NZP4	Strongylocentrotus purpuratus	O
MONBE\|EnsemblGenome=MONBRDRAFT_28738\|UniProtKB=A9V918	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34360\|UniProtKB=A9VB55	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_28502\|UniProtKB=A9V8C6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_28715\|UniProtKB=A9V8Z4	Monosiga brevicollis	O
ASPFU\|EnsemblGenome=AFUA_4G13800\|UniProtKB=Q4WQS0	Neosartorya fumigata	O
TRIV3\|Gene_ORFName=TVAG_301370\|UniProtKB=A2E5F9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_499550\|UniProtKB=A2EIP2	Trichomonas vaginalis	O
BACTN\|EnsemblGenome=BT_3608\|UniProtKB=Q8A1Q1	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB3006\|UniProtKB=Q7UUX1	Rhodopirellula baltica	O
STRR6\|EnsemblGenome=spr1531\|UniProtKB=Q8CWP8	Streptococcus pneumoniae	O
STRR6\|EnsemblGenome=spr1536\|UniProtKB=P62576	Streptococcus pneumoniae	O
BACTN\|EnsemblGenome=BT_0455\|UniProtKB=Q8AAK9	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB8895\|UniProtKB=Q7UMD4	Rhodopirellula baltica	O
VIBCH\|EnsemblGenome=VC_1784\|UniProtKB=P0C6E9	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA2794\|UniProtKB=G3XCV3	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0928\|UniProtKB=P29768	Salmonella typhimurium	O