PANTHER Gene Information

Gene Symbol(s):

Tb08.26N11.280

Organism:

Trypanosoma brucei

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Gene Name:

Pitrilysin-like metalloprotease

Gene ID:

Tb927.8.1860

Protein ID:

Q581Z6

Persistent Id:

PTN002453141

Alternate Ids:

AAX79407(EMBL-CDS)	3659170(GeneID)
CP000071(EMBL)	Q581Z6(Synonym)
XM_841926(refSeq)	72392437(GI)
Q581Z6_TRYB2(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	PRESEQUENCE PROTEASE (PTHR43016)
PANTHER Subfamily:	PRESEQUENCE PROTEASE, MITOCHONDRIAL (PTHR43016:SF13)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	metalloprotease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	metalloendopeptidase activity
GO BP Complete:	proteolysis, protein processing
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17663\|UniProtKB=Q5JRX3	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002244.7\|UniProtKB=H2R1S7	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000004938.4\|UniProtKB=F7A1F3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1916867\|UniProtKB=Q8K411	Mus musculus	LDO
RAT\|RGD=1310998\|UniProtKB=A0A0G2K6D5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002685.6\|UniProtKB=F1MFA3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011157.5\|UniProtKB=A0A287BCS4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000398.3\|UniProtKB=A0A9L0SK33	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003238.6\|UniProtKB=A0A5F5XWB5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003172.1\|UniProtKB=A0A8I3MRV7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006591.4\|UniProtKB=A0A5F8H771	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006085.3\|UniProtKB=A0A6I8NDF6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010005485.1\|UniProtKB=A0A8V0XRX1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008286.4\|UniProtKB=G1KHM5	Anolis carolinensis	LDO
XENLA\|Gene=pitrm1.L\|UniProtKB=A0A1L8FVA3	Xenopus laevis	O
XENLA\|Gene=pitrm1\|UniProtKB=Q6PF24	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-952658\|UniProtKB=Q28BR5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005710.3\|UniProtKB=H2LMA6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2876\|UniProtKB=Q7ZVZ6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010785.1\|UniProtKB=W5MXW4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007312.3\|UniProtKB=F6Z3I0	Ciona intestinalis	LDO
STRPU\|EnsemblGenome=LOC588072\|UniProtKB=A0A7M7RFD1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020757\|UniProtKB=Q9TZ33	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037976\|UniProtKB=A8XTN0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00098223\|UniProtKB=A0A2A6C7M5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0033005\|UniProtKB=Q9V9E3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP006616\|UniProtKB=Q7Q564	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC010168\|UniProtKB=D6WT63	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_310892\|UniProtKB=E9FVX4	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG193706\|UniProtKB=T1FVA2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88690\|UniProtKB=A7RPA0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG25744\|UniProtKB=B3RYN5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_25023\|UniProtKB=A9UXJ5	Monosiga brevicollis	LDO
YEAST\|SGD=S000002838\|UniProtKB=P32898	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADR184W\|UniProtKB=Q759T9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000201699\|UniProtKB=Q5A301	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F21615g\|UniProtKB=Q6C0U8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03853\|UniProtKB=Q5B6H7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G07910\|UniProtKB=Q4WP38	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01272\|UniProtKB=Q7S7C0	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_12205\|UniProtKB=A7F2Q7	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03534\|UniProtKB=Q0UXI0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC119.17\|UniProtKB=O42908	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04533\|UniProtKB=B6K729	Schizosaccharomyces japonicus	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_34122\|UniProtKB=F4NRE5	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_124430\|UniProtKB=C4LZH9	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0271506\|UniProtKB=Q8MP58	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_158791\|UniProtKB=F1A2H7	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_07_0100\|UniProtKB=Q4QIT4	Leishmania major	LDO
GIAIC\|EnsemblGenome=GL50803_9508\|UniProtKB=A8BNI1	Giardia intestinalis	LDO
GIAIC\|EnsemblGenome=GL50803_93551\|UniProtKB=A8BTG2	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_317610\|UniProtKB=A2FTL0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_016860\|UniProtKB=A2ER24	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_371040\|UniProtKB=A2G6B8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_484640\|UniProtKB=A2F1Z2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_087590\|UniProtKB=A2FDT5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_151080\|UniProtKB=A2FM20	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1360800\|UniProtKB=Q76NL8	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00031746001\|UniProtKB=A0BSJ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009763001\|UniProtKB=A0CRN1	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_264129\|UniProtKB=B8CC58	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_22863\|UniProtKB=B8C3L2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GVT4_PHYRM\|UniProtKB=H3GVT4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_01g020918v5\|UniProtKB=A0A2K3E651	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00126p00013900\|UniProtKB=W1NN83	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_68G00860\|UniProtKB=A0A0K9NSC0	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g14630\|UniProtKB=A0A804KJK5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016164mg\|UniProtKB=K3YPH2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G307100\|UniProtKB=A0A194YTJ5	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb255690\|UniProtKB=A0A804PNL1	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_3g58166v3\|UniProtKB=I1IEX5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0616430\|UniProtKB=F2CRM6	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G343300\|UniProtKB=A0A3B6PQ08	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G292700\|UniProtKB=A0A3B6QKG3	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G313400\|UniProtKB=A0A3B6NU14	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_015546\|UniProtKB=A0A1U8ANJ0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110790868\|UniProtKB=A0A9R0IL32	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0304721\|UniProtKB=A0A251UD24	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200061400\|UniProtKB=A0A9R1WIF4	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0448081\|UniProtKB=A0A251TKR0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500270780\|UniProtKB=A0A9R1X9R3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000907mg\|UniProtKB=A0A022RD97	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_33015\|UniProtKB=A0A2G2Y051	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400025820\|UniProtKB=M1CFH9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g108600.3\|UniProtKB=A0A3Q7ESN3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107820951\|UniProtKB=A0A1S4CNI5	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107815835\|UniProtKB=A0A1S4C789	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi03g00485\|UniProtKB=F6HQC5	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G01465\|UniProtKB=A0A059BD29	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00039059001\|UniProtKB=A0A078GSF0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A06P03570.1\|UniProtKB=A0A078ILX4	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra018811\|UniProtKB=M4DQL8	Brassica campestris	LDO
ARATH\|TAIR=locus=2012176\|UniProtKB=Q8VY06	Arabidopsis thaliana	LDO
BRANA\|EnsemblGenome=GSBRNA2T00065272001\|UniProtKB=A0A078JQH7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00005618001\|UniProtKB=A0A078G0P4	Brassica napus	O
BRACM\|EnsemblGenome=Bra037536\|UniProtKB=M4F8X4	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C03P50190.1\|UniProtKB=A0A078GEC9	Brassica napus	O
BRACM\|EnsemblGenome=Bra001738\|UniProtKB=M4CC08	Brassica campestris	O
ARATH\|TAIR=locus=2094138\|UniProtKB=Q9LJL3	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107940729\|UniProtKB=A0A1U8MVW5	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_007031\|UniProtKB=A0A061E0T6	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_004G142300v3\|UniProtKB=A0A2K2AUM6	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_009G103700v3\|UniProtKB=A0A2K1Z5T3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_10G066200\|UniProtKB=A0A2C9V404	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0813880\|UniProtKB=B9RY20	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_01G244900\|UniProtKB=A0A0R4J2L6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g004680\|UniProtKB=A0A072UDY2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr13_05950\|UniProtKB=A0A2I4FV98	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G073760\|UniProtKB=A0A0A0K809	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G122200\|UniProtKB=A0A251MWT2	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_8G122100\|UniProtKB=A0A251MWU3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_419272\|UniProtKB=D8S8E0	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_152047\|UniProtKB=D8S2U3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c5_3160\|UniProtKB=A0A2K1KI97	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0813s0001\|UniProtKB=A0A2R6VYD9	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0138s0034\|UniProtKB=A0A2R6W6X3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_005600040\|UniProtKB=A0A1Y1INT0	Klebsormidium nitens	LDO