PANTHER Gene Information

Gene Symbol(s):

Tb08.29H22.450

Organism:

Trypanosoma brucei

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Gene Name:

Adenosine deaminase

Gene ID:

Tb927.8.4270

Protein ID:

Q57W08

Persistent Id:

PTN002261427

Alternate Ids:

CP000071(EMBL)	XP_847258(refSeq)
AAX70211(EMBL-CDS)	70803288(GI)
3659432(GeneID)	Q57W08(Synonym)
Q57W08_TRYB2(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ADENOSINE DEAMINASE (PTHR11409)
PANTHER Subfamily:	ADENOSINE DEAMINASE-LIKE PROTEIN (PTHR11409:SF42)
PANTHER GO-slim Molecular Function:	adenosine deaminase activity
PANTHER GO-slim Biological Process:	small molecule biosynthetic process nucleobase-containing compound biosynthetic process purine-containing compound biosynthetic process purine nucleoside catabolic process adenosine metabolic process purine nucleobase metabolic process carbohydrate derivative biosynthetic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	deaminase

Pathway Categories:

Adenine and hypoxanthine salvage pathway

Deoxyadenosine deaminase

Adenine and hypoxanthine salvage pathway

Adenosine deaminase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	adenosine deaminase activity
GO BP Complete:	adenosine catabolic process, inosine biosynthetic process
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1839\|UniProtKB=Q9NZK5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014036.5\|UniProtKB=A0A2J8Q1Z0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007790.3\|UniProtKB=G3QXR5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002529.4\|UniProtKB=F7GX39	Macaca mulatta	O
BOVIN\|Ensembl=ENSBTAG00000017313.6\|UniProtKB=F1N144	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000035218.3\|UniProtKB=A0A287BDN3	Sus scrofa	O
PIG\|Gene=ADA2\|UniProtKB=P58780	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000046556.1\|UniProtKB=F6ZNG8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000012168.6\|UniProtKB=A0A2I2U868	Felis catus	O
MONDO\|Ensembl=ENSMODG00000018443.3\|UniProtKB=F7CUH1	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002303.2\|UniProtKB=F7AK06	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011860.1\|UniProtKB=F1NML7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012247.4\|UniProtKB=G1KM25	Anolis carolinensis	O
XENLA\|Gene=ada2.S\|UniProtKB=A0A1L8GQN6	Xenopus laevis	O
XENLA\|Gene=ada2\|UniProtKB=Q2VQV9	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000044241\|UniProtKB=A0A803JM66	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015798.2\|UniProtKB=H2MM44	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-041210-77\|UniProtKB=F6NKG5	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000015874.2\|UniProtKB=H2MME2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030902-4\|UniProtKB=P58781	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016578.1\|UniProtKB=W5NIL8	lepisosteus oculatus	O
BRAFL\|Gene=LOC118425705\|UniProtKB=A0A9J7LY73	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC583310\|UniProtKB=A0A7M7P2H0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100894124\|UniProtKB=A0A7M7P2A7	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0036751\|UniProtKB=Q9VVK4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0043025\|UniProtKB=Q8IQR3	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033952\|UniProtKB=Q7KGG1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0038172\|UniProtKB=Q9VFS1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0038173\|UniProtKB=Q9VFS0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036752\|UniProtKB=Q9VVK5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005283\|UniProtKB=Q7QI64	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006906\|UniProtKB=A0A1S4GU77	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006907\|UniProtKB=Q7QIJ5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003178\|UniProtKB=D6WEK1	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC003279\|UniProtKB=D6WEK0	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307202\|UniProtKB=E9H0U5	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG112911\|UniProtKB=T1EFN3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82370\|UniProtKB=T1G4R4	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG134508\|UniProtKB=T1EI50	helobdella robusta	O
EMENI\|EnsemblGenome=ANIA_02494\|UniProtKB=Q5BAD6	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_05492\|UniProtKB=C8VGC5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G15090\|UniProtKB=Q4WZ26	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_6G13180\|UniProtKB=Q4WLK7	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU04048\|UniProtKB=Q7RZG8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_00352\|UniProtKB=A7E4Y0	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_10346\|UniProtKB=Q0UD18	Phaeosphaeria nodorum	O
NEUCR\|EnsemblGenome=NCU04642\|UniProtKB=V5IL15	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_00879\|UniProtKB=A7E6F4	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_11491\|UniProtKB=Q0U9S3	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01794\|UniProtKB=A0A0D1E3E4	Ustilago maydis	O
DICDI\|dictyBase=DDB_G0275179\|UniProtKB=Q553U5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_48090\|UniProtKB=F0ZMR4	Dictyostelium purpureum	O
HUMAN\|HGNC=31853\|UniProtKB=Q6DHV7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006991.6\|UniProtKB=H2Q9A4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015145.3\|UniProtKB=G3RGN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017067.4\|UniProtKB=A0A1D5R8D4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923144\|UniProtKB=Q80SY6	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000014476.5\|UniProtKB=F1N1T1	Bos taurus	O
BOVIN\|Gene=ADAL\|UniProtKB=Q0VC13	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000004710.5\|UniProtKB=F1SI59	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014340.4\|UniProtKB=F7DTZ5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013329.6\|UniProtKB=M3WIN5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845022940.1\|UniProtKB=A0A8I3PTR4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017822.4\|UniProtKB=F6ZXC8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000038255.1\|UniProtKB=A0A6I8NF53	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024897.1\|UniProtKB=A0A8V1A525	Gallus gallus	LDO
XENLA\|Gene=LOC446867\|UniProtKB=A0A1L8GT51	Xenopus laevis	O
XENLA\|Gene=adal-a\|UniProtKB=Q4V831	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5873451\|UniProtKB=F6WHH6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004847.2\|UniProtKB=H2LJB8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050913-145\|UniProtKB=Q4V9P6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014596.1\|UniProtKB=W5NBF3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021692.1\|UniProtKB=H2XZK6	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118409276\|UniProtKB=A0A9J7KJB1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589264\|UniProtKB=A0A7M7N8C2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00016632\|UniProtKB=Q8IG39	Caenorhabditis elegans	LDO
DROME\|FlyBase=FBgn0037661\|UniProtKB=Q9VHH7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005158\|UniProtKB=Q7Q9M2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC010107\|UniProtKB=D6WSK3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_322499\|UniProtKB=E9GW70	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG110129\|UniProtKB=T1EEZ6	helobdella robusta	LDO
EMENI\|EnsemblGenome=ANIA_00662\|UniProtKB=C8VRT4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G13240\|UniProtKB=A4GYZ1	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00438\|UniProtKB=Q7RXS1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03484\|UniProtKB=A7EDU4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_16046\|UniProtKB=Q0TWX4	Phaeosphaeria nodorum	LDO
USTMA\|EnsemblGenome=UMAG_00564\|UniProtKB=A0A0D1EA55	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_20019\|UniProtKB=F4P626	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_005040\|UniProtKB=C4M098	Entamoeba histolytica	LDO
LEIMA\|EnsemblGenome=LMJF_10_0840\|UniProtKB=Q4QHD0	Leishmania major	LDO
PARTE\|EnsemblGenome=GSPATT00004773001\|UniProtKB=A0BIN4	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_37724\|UniProtKB=B8CD03	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HEA8_PHYRM\|UniProtKB=H3HEA8	Phytophthora ramorum	O
PHYRM\|Gene=H3GVM4_PHYRM\|UniProtKB=H3GVM4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g161000v5\|UniProtKB=A0A2K3DWE2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00062p00059690\|UniProtKB=U5DGJ5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_38G01020\|UniProtKB=A0A0K9P4Q6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g00790\|UniProtKB=A0A804KR63	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_030174mg\|UniProtKB=K3ZU93	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G405200\|UniProtKB=C5X4S2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb110820\|UniProtKB=A0A804MTR4	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os07g0661000\|UniProtKB=Q8H3U7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g18815v3\|UniProtKB=I1GRH9	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_1g11465v3\|UniProtKB=A0A0Q3GTD7	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_1g18810v3\|UniProtKB=I1GRH8	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0116500\|UniProtKB=A0A8I6X315	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2D02G129800\|UniProtKB=A0A3B6DB89	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G129900\|UniProtKB=A0A3B6D8C0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G127600\|UniProtKB=A0A3B6ATG7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS2D02G130200\|UniProtKB=A0A3B6D826	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G127500\|UniProtKB=A0A3B6AUB2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G149500\|UniProtKB=A0A3B6C140	Triticum aestivum	LDO
NELNU\|Gene=LOC104610888\|UniProtKB=A0A1U8B582	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104604849\|UniProtKB=A0A1U8AXD3	Nelumbo nucifera	O
SPIOL\|Gene=LOC110790735\|UniProtKB=A0A9R0JYG5	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0753891\|UniProtKB=A0A251RZM2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400180300\|UniProtKB=A0A9R1VT73	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a008719mg\|UniProtKB=A0A022QMV2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_25062\|UniProtKB=A0A2G2YJN9	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400011257\|UniProtKB=M1ASJ3	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g005310.3\|UniProtKB=A0A3Q7I9E4	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107769250\|UniProtKB=A0A1S3XVG9	Nicotiana tabacum	O
TOBAC\|Gene=LOC107794872\|UniProtKB=A0A1S4A8D5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00044\|UniProtKB=A5C4M9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D01304\|UniProtKB=A0A059CF19	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P26050.1\|UniProtKB=A0A078FUH6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029523\|UniProtKB=M4EL56	Brassica campestris	LDO
ARATH\|TAIR=locus=2138967\|UniProtKB=Q8LPL7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107961981\|UniProtKB=A0A1U8PR56	Gossypium hirsutum	O
GOSHI\|Gene=LOC107901944\|UniProtKB=A0A1U8J4P9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030190\|UniProtKB=A0A061GGH1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g017943mg\|UniProtKB=A0A067GJ72	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_011G000100v3\|UniProtKB=U7E1R7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G010200\|UniProtKB=A0A2C9U8L8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0905310\|UniProtKB=B9RXP2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G015300\|UniProtKB=A0A0R0F6Y7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_07G258900\|UniProtKB=I1KNB5	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g131840\|UniProtKB=G7JI14	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_13G206500\|UniProtKB=I1M119	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G106200\|UniProtKB=I1MFF9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g022780\|UniProtKB=A0A072VF98	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr04_14390\|UniProtKB=A0A2I4FPB7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G514840\|UniProtKB=A0A0A0KHV0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G024100\|UniProtKB=A0A251PEM7	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_87459\|UniProtKB=D8R7L9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_138763\|UniProtKB=D8TG07	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c11_7970\|UniProtKB=A0A2K1JTV9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0023s0135\|UniProtKB=A0A2R6XCK1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003780170\|UniProtKB=A0A1Y1IFF9	Klebsormidium nitens	LDO
CHLAA\|EnsemblGenome=Caur_3337\|UniProtKB=A9WJQ7	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO7268\|UniProtKB=Q9X7T2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4901\|UniProtKB=Q9AK25	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3313c\|UniProtKB=P63907	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO0991\|UniProtKB=A5I0I2	Clostridium botulinum	O
GLOVI\|Gene=Q7NPD4_GLOVI\|UniProtKB=Q7NPD4	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_3969\|UniProtKB=Q8EZ87	Leptospira interrogans	O
LEPIN\|EnsemblGenome=LA_3783\|UniProtKB=Q8EZR9	Leptospira interrogans	O
SHEON\|Gene_OrderedLocusName=SO_4731\|UniProtKB=Q8E8D4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_2751\|UniProtKB=Q9KNI7	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0294\|UniProtKB=Q8PDP1	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM1463\|UniProtKB=Q8ZPL9	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA15374\|UniProtKB=P22333	Escherichia coli	O