PANTHER Gene Information

Gene Symbol(s):

scnn1a

Organism:

Xenopus laevis

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Tree

Gene Name:

Amiloride-sensitive sodium channel subunit alpha

Gene ID:

scnn1a

Protein ID:

P51167

Persistent Id:

PTN008977729

Alternate Ids:

397811(GeneID)	Nonvoltage-gated sodium channel 1 subunit alpha(Synonym)
NP_001081392(refSeq)	968936(GI)
scnn1a(Symbol)	AAA74970(EMBL-CDS)
SCNNA_XENLA(UniProtKB-ID)	U23535(EMBL)
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PANTHER Classification

PANTHER Family:	AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED (PTHR11690)
PANTHER Subfamily:	AMILORIDE-SENSITIVE SODIUM CHANNEL SUBUNIT ALPHA (PTHR11690:SF124)
PANTHER GO-slim Molecular Function:	sodium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	sodium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ligand-gated sodium channel activity
GO BP Complete:	sodium ion transmembrane transport
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10599\|UniProtKB=P37088	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004571\|UniProtKB=H2Q5A1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010834.3\|UniProtKB=A0A2I2YQN1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020212.4\|UniProtKB=F6V9V4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=101782\|UniProtKB=Q61180	Mus musculus	LDO
RAT\|RGD=3639\|UniProtKB=P37089	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002631\|UniProtKB=P55270	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000707.5\|UniProtKB=A0A480QJ99	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000001443.3\|UniProtKB=A0A9L0TJP6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006869.6\|UniProtKB=A0A2I2URC6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029331.1\|UniProtKB=A0A8I3Q679	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000001688.3\|UniProtKB=A0A6I8PB29	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021866.1\|UniProtKB=A0A8V0ZTC6	Gallus gallus	LDO
CHICK\|Gene=SCNN1A\|UniProtKB=Q92075	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006704\|UniProtKB=H9GBX2	Anolis carolinensis	LDO
XENTR\|Xenbase=XB-GENE-996083\|UniProtKB=F7AE39	Xenopus tropicalis	LDO
BRAFL\|Gene=LOC118428532\|UniProtKB=A0A9J7N9P2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409427\|UniProtKB=A0A9J7HVH7	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118409702\|UniProtKB=A0A9J7KMS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429346\|UniProtKB=A0A9J7NAG0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892792\|UniProtKB=A0A7M7N8Z6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891497\|UniProtKB=A0A7M7SUT4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580984\|UniProtKB=A0A7M7HLK0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441174\|UniProtKB=A0A7M7HF55	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100894064\|UniProtKB=A0A7M7SUH3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891818\|UniProtKB=A0A7M7NFP2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891272\|UniProtKB=A0A7M7SV08	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594671\|UniProtKB=A0A7M7PLZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893645\|UniProtKB=A0A7M7LW68	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889460\|UniProtKB=A0A7M7HQL8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889526\|UniProtKB=A0A7M7HK48	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590960\|UniProtKB=A0A7M7N8K7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105436466\|UniProtKB=A0A7M7N8V4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890654\|UniProtKB=A0A7M7N7N9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446529\|UniProtKB=A0A7M7SUJ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891438\|UniProtKB=A0A7M7N919	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763355\|UniProtKB=A0A7M7GA14	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012116\|UniProtKB=P91835	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00319\|UniProtKB=A8WMP7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112486\|UniProtKB=A0A2A6CCV0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277773\|UniProtKB=A0A2A6CCE7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00012137\|UniProtKB=Q22851	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11871\|UniProtKB=A8XE73	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00280100\|UniProtKB=A0A2A6CNI2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095582\|UniProtKB=A0A2A6C4I7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116949\|UniProtKB=A0A2A6CKV1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279138\|UniProtKB=A0A2A6C436	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096276\|UniProtKB=A0A2A6BKI1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101632\|UniProtKB=A0A2A6BNT5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00104647\|UniProtKB=A0A2A6B9T3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00118917\|UniProtKB=A0A2A6CKT1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101834\|UniProtKB=A0A2A6CMD1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095667\|UniProtKB=A0A2A6C296	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117455\|UniProtKB=A0A2A6CGP7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272665\|UniProtKB=A0A2A6CL11	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101230\|UniProtKB=A0A2A6BXY3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00000950\|UniProtKB=P24585	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16785\|UniProtKB=A8XPT2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00093227\|UniProtKB=A0A2A6CPP4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00093226\|UniProtKB=A0A2A6B2S3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279530\|UniProtKB=A0A2A6CM49	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00275338\|UniProtKB=A0A2A6BFR6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006748\|UniProtKB=Q21974	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05805\|UniProtKB=A8X1K9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00006832\|UniProtKB=Q09274	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00750\|UniProtKB=A8WN53	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00099877\|UniProtKB=A0A2A6B6V6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015957\|UniProtKB=Q18077	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034808\|UniProtKB=A8XJL2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095216\|UniProtKB=A0A2A6CTU1	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018906\|UniProtKB=Q20852	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013486\|UniProtKB=Q9U1T9	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013480\|UniProtKB=Q9XTS9	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00013487\|UniProtKB=Q9U1T8	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00278527\|UniProtKB=A0A2A6C4X9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117929\|UniProtKB=A0A2A6CKC6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00282848\|UniProtKB=A0A2A6BSU9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096858\|UniProtKB=A0A2A6C5A6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101875\|UniProtKB=A0A2A6CSQ8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272170\|UniProtKB=A0A2A6BSL6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096852\|UniProtKB=A0A2A6C5E4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095605\|UniProtKB=A0A2A6C3N7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00000952\|UniProtKB=Q19038	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG07259\|UniProtKB=A8X543	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00089711\|UniProtKB=A0A2A6BEQ4	Pristionchus pacificus	LDO
CAEEL\|WormBase=WBGene00003174\|UniProtKB=P34886	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041260\|UniProtKB=Q60NC0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272421\|UniProtKB=A0A2A6BBZ6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003168\|UniProtKB=P24612	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036254\|UniProtKB=Q17298	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00275832\|UniProtKB=A0A8R1YZS0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091439\|UniProtKB=A0A2A6C9S0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00010334\|UniProtKB=G5EFH3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG17520\|UniProtKB=A8XRD5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00022815\|UniProtKB=O01635	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG11997\|UniProtKB=A8XEB1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00278793\|UniProtKB=A0A2A6C4B2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117196\|UniProtKB=A0A2A6BU03	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272164\|UniProtKB=A0A2A6BSZ7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00098838\|UniProtKB=A0A2A6CCT1	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032602\|UniProtKB=Q9VJI4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010146\|UniProtKB=Q7Q0V0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005481\|UniProtKB=D6WY25	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW017829\|UniProtKB=B7PEV5	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW028495\|UniProtKB=A0A905FYF3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002325\|UniProtKB=A0A1S4KQ07	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023720\|UniProtKB=B7QI61	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213150\|UniProtKB=A7SJB5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218891\|UniProtKB=A7SX71	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136400\|UniProtKB=A7SX80	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211338\|UniProtKB=A7SF69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215544\|UniProtKB=A7SPS2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215206\|UniProtKB=A7SP23	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211570\|UniProtKB=A7SFR0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205746\|UniProtKB=A7S2F2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211334\|UniProtKB=A7SF65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211571\|UniProtKB=A7SFR1	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54579\|UniProtKB=B3RSF6	Trichoplax adhaerens	LDO