PANTHER Gene Information

Gene Symbol(s):

sesn3.S

Organism:

Xenopus laevis

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Gene Name:

Sestrin-3

Gene ID:

sesn3.S

Protein ID:

A0A1L8HAZ1

Persistent Id:

PTN008996913

Alternate Ids:

108710010(GeneID)	A0A1L8HAZ1(Synonym)
XP_018105838(refSeq)	A0A1L8HAZ1_XENLA(UniProtKB-ID)
1069333609(GI)
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PANTHER Classification

PANTHER Family:	P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN (PTHR12474)
PANTHER Subfamily:	SESTRIN-3 (PTHR12474:SF4)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on peroxide as acceptor amino acid binding
PANTHER GO-slim Biological Process:	positive regulation of macroautophagy negative regulation of TORC1 signaling cellular response to oxygen-containing compound cellular response to amino acid starvation cellular response to organonitrogen compound
PANTHER GO-slim Cellular Component:
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-leucine binding, oxidoreductase activity, acting on peroxide as acceptor
GO BP Complete:	positive regulation of macroautophagy, regulation of response to reactive oxygen species, negative regulation of TORC1 signaling, cellular response to L-leucine, cellular response to leucine starvation
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=23060\|UniProtKB=P58005	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004192.6\|UniProtKB=K7CXR4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004922.3\|UniProtKB=G3QQF9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009394.4\|UniProtKB=F7HEU9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1922997\|UniProtKB=Q9CYP7	Mus musculus	LDO
RAT\|RGD=1309470\|UniProtKB=A0A8I6A0N4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004034.6\|UniProtKB=F1MFJ7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000037015.3\|UniProtKB=A0A287A0W1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017743.4\|UniProtKB=A0A9L0RJB0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005081.6\|UniProtKB=A0A337SQV6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018942.1\|UniProtKB=A0A8I3NX72	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000000163.4\|UniProtKB=F6XS87	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010503.4\|UniProtKB=A0A6I8MX44	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008386.1\|UniProtKB=A0A8V0XTS4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013850.3\|UniProtKB=G1KPC2	Anolis carolinensis	LDO
XENTR\|Xenbase=XB-GENE-494676\|UniProtKB=A0A6I8SKA8	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2924\|UniProtKB=F1R1P4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007583.1\|UniProtKB=W5MLE5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007668.3\|UniProtKB=F6T7E5	Ciona intestinalis	O
BRAFL\|Gene=LOC118423082\|UniProtKB=A0A9J7LQS3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC584902\|UniProtKB=A0A7M7PFI8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00022279\|UniProtKB=Q9N4D6	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG03915\|UniProtKB=A8WVR0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117377\|UniProtKB=A0A2A6BL70	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0034897\|UniProtKB=Q9W1K5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007169\|UniProtKB=Q7PTB1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003553\|UniProtKB=D6WHQ5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_200622\|UniProtKB=E9H5P4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW002773\|UniProtKB=B7P7V9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG117076\|UniProtKB=T1EGK0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185938\|UniProtKB=T1FNG7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g188161\|UniProtKB=A7SCG7	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG25289\|UniProtKB=B3RYA9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_1017\|UniProtKB=A9UW02	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0279427\|UniProtKB=Q54WU6	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_98918\|UniProtKB=F0ZUS8	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_18_0650\|UniProtKB=Q4QDX6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.05.0190\|UniProtKB=Q388Q1	Trypanosoma brucei	O
PARTE\|EnsemblGenome=GSPATT00006213001\|UniProtKB=A0C4J8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00023191001\|UniProtKB=A0E401	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00009541001\|UniProtKB=A0CR11	Paramecium tetraurelia	O
PHYRM\|Gene=H3GGE2_PHYRM\|UniProtKB=H3GGE2	Phytophthora ramorum	O