PANTHER Gene Information

Gene Symbol(s):

brip1

Organism:

Xenopus tropicalis

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Gene Name:

BRCA1-interacting protein C-terminal helicase 1

Gene ID:

XB-GENE-492370

Protein ID:

A0A6I8Q5G6

Persistent Id:

PTN000158335

Alternate Ids:

301608630(GI)	XP_002933884(refSeq)
ENSXETG00000010720(Ensembl)	A0A6I8Q5G6_XENTR(UniProtKB-ID)
100489959(GeneID)	A0A6I8Q5G6(Synonym)
ENSXETT00000101166(Ensembl_TRS)	ENSXETP00000064759(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily:	FANCONI ANEMIA GROUP J PROTEIN (PTHR11472:SF47)
PANTHER GO-slim Molecular Function:	DNA helicase activity
PANTHER GO-slim Biological Process:	double-strand break repair nucleotide-excision repair reciprocal meiotic recombination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, ATP binding, DNA helicase activity, metal ion binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, helicase activity, iron-sulfur cluster binding, hydrolase activity, isomerase activity
GO BP Complete:	DNA repair, nucleotide-excision repair, nucleobase-containing compound metabolic process, double-strand break repair involved in meiotic recombination
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cell Cycle, Processing of DNA double-strand break ends, Regulation of TP53 Activity through Phosphorylation, Gene expression (Transcription), HDR through Single Strand Annealing (SSA), Cell Cycle Checkpoints, DNA Double-Strand Break Repair, Generic Transcription Pathway, G2/M DNA damage checkpoint, RNA Polymerase II Transcription, G2/M Checkpoints, Transcriptional Regulation by TP53, Homology Directed Repair, Regulation of TP53 Activity, HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), DNA Repair

Orthologs

ID	Organism	Type
HUMAN\|HGNC=20473\|UniProtKB=Q9BX63	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009493.4\|UniProtKB=H2QDL5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008859.4\|UniProtKB=G3R0I1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009027.4\|UniProtKB=F7FGY3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2442836\|UniProtKB=Q5SXJ3	Mus musculus	LDO
RAT\|RGD=1307659\|UniProtKB=A0A0G2K475	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012068.7\|UniProtKB=F1MMS0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000021384.4\|UniProtKB=A0A287AQ29	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024392.4\|UniProtKB=A0A9L0RD48	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000018470.5\|UniProtKB=M3WNS1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845027066.1\|UniProtKB=A0A8I3Q1K5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014258.3\|UniProtKB=F6XJI0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011526.3\|UniProtKB=F6S8U0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029319\|UniProtKB=Q3YK19	Gallus gallus	LDO
XENLA\|Gene=brip1.L\|UniProtKB=A0A8J1M6B6	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000014821.2\|UniProtKB=A0A3B3H805	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-081107-11\|UniProtKB=B7ZDD5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005046.1\|UniProtKB=W5MCG4	lepisosteus oculatus	LDO
STRPU\|EnsemblGenome=LOC576476\|UniProtKB=A0A7M7PEE1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001049\|UniProtKB=O62217	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19723\|UniProtKB=A8XWG9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00090524\|UniProtKB=A0A2A6BP98	Pristionchus pacificus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_311920\|UniProtKB=E9FYB4	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_48831\|UniProtKB=E9GD07	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW019247\|UniProtKB=B7PW21	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG189813\|UniProtKB=T1FRE0	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG30066\|UniProtKB=B3S6C0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26081\|UniProtKB=A9V1B4	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_1044\|UniProtKB=F4P1J7	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_054240\|UniProtKB=C4M6T8	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0286621\|UniProtKB=Q54LI7	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_5561\|UniProtKB=F1A2C9	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_28_1600\|UniProtKB=Q4Q8A5	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.1100\|UniProtKB=Q383Z6	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_5631\|UniProtKB=A8B495	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_067090\|UniProtKB=A2DSC5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_445200\|UniProtKB=A2E4I6	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_5916\|UniProtKB=B8C513	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GHW5_PHYRM\|UniProtKB=H3GHW5	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G7G4_PHYRM\|UniProtKB=H3G7G4	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_09g397350v5\|UniProtKB=A0A2K3DD36	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00044p00154010\|UniProtKB=U5D9X9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_40G00190\|UniProtKB=A0A0K9P2W6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g07030\|UniProtKB=A0A804L552	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_028742mg\|UniProtKB=K3ZQ62	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G290000\|UniProtKB=A0A1W0W690	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb320860\|UniProtKB=A0A1D6IAW0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0551800\|UniProtKB=A0A0P0XQZ3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g37260v3\|UniProtKB=A0A0Q3LFA9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0503930\|UniProtKB=A0A8I6XRQ3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G359700\|UniProtKB=A0A3B6MV98	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G352700\|UniProtKB=A0A3B6KNE2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G354900\|UniProtKB=A0A3B6LQP8	Triticum aestivum	LDO
NELNU\|Gene=LOC104606809\|UniProtKB=A0A1U8B425	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110795306\|UniProtKB=A0A9R0IUZ0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr06g0185191\|UniProtKB=A0A251UK31	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0278181\|UniProtKB=A0A9K3IWN5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200051770\|UniProtKB=A0A9R1WEV9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a020299mg\|UniProtKB=A0A022RU02	Erythranthe guttata	LDO
TOBAC\|Gene=LOC107767657\|UniProtKB=A0A1S3XQT2	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107816608\|UniProtKB=A0A1S4C9L2	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_18s0122g01130\|UniProtKB=F6I6T9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F03572\|UniProtKB=A0A059BXF6	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00043200001\|UniProtKB=A0A078GSP7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00050974001\|UniProtKB=A0A078JE65	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra036693\|UniProtKB=M4F6I3	Brassica campestris	O
BRACM\|EnsemblGenome=Bra025840\|UniProtKB=M4EAN1	Brassica campestris	LDO
ARATH\|TAIR=locus=2030412\|UniProtKB=F4HUN8	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2030497\|UniProtKB=A0A1P8AV25	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107905758\|UniProtKB=A0A1U8JCE9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905720\|UniProtKB=A0A1U8JCA7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034410\|UniProtKB=A0A061FLD2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g000814mg\|UniProtKB=A0A067GZJ3	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G008700v3\|UniProtKB=A0A2K2BBI5	Populus trichocarpa	LDO
POPTR\|Gene_ORFName=POPTR_T051350\|UniProtKB=A0A3N7FDU7	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_18G003800\|UniProtKB=A0A2C9TZF7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1601590\|UniProtKB=B9R8Q0	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_14G223700\|UniProtKB=A0A0R0GTX9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g026490\|UniProtKB=A0A072VE13	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_18410\|UniProtKB=A0A2I4GWI7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G663720\|UniProtKB=A0A0A0L1D4	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_4G663710\|UniProtKB=A0A0A0L4M2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G009400\|UniProtKB=A0A251P1N9	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_408754\|UniProtKB=D8R9V1	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c10_650\|UniProtKB=A0A2K1JX49	Physcomitrella patens	LDO
KLENI\|Gene_ORFName=KFL_000250470\|UniProtKB=A0A1Y1HPN3	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1439\|UniProtKB=B1L6V6	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1088\|UniProtKB=B1L5V5	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0313\|UniProtKB=Q980I2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE3526\|UniProtKB=Q8ZSY2	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE2991\|UniProtKB=Q8ZU14	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_2096\|UniProtKB=Q8TP28	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0335\|UniProtKB=Q8TTU0	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_0942\|UniProtKB=Q58352	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1383G\|UniProtKB=Q9HQ08	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2476C\|UniProtKB=Q9HMM1	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2441G\|UniProtKB=Q9HMP9	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK0784\|UniProtKB=Q5JH96	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_1621\|UniProtKB=A9WBN2	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO5802\|UniProtKB=O69978	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1329c\|UniProtKB=P9WMR5	Mycobacterium tuberculosis	O
LISMO\|Gene=dinG\|UniProtKB=Q8Y604	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_22150\|UniProtKB=P50831	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1565\|UniProtKB=Q81FL6	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_22400\|UniProtKB=P54394	Bacillus subtilis	O
GLOVI\|Gene=Q7NKM8_GLOVI\|UniProtKB=Q7NKM8	Gloeobacter violaceus	O
SYNY3\|Gene=P72618_SYNY3\|UniProtKB=P72618	Synechocystis	O
GLOVI\|Gene=Q7NN01_GLOVI\|UniProtKB=Q7NN01	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_1875\|UniProtKB=Q8F513	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB8062\|UniProtKB=Q7UG83	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_358\|UniProtKB=O66684	Aquifex aeolicus	O
FUSNN\|EnsemblGenome=FN0743\|UniProtKB=Q8RFF8	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB0287\|UniProtKB=Q9K181	Neisseria meningitidis serogroup b	O
SHEON\|Gene_OrderedLocusName=SO_1819\|UniProtKB=Q8EFZ5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1855\|UniProtKB=Q9KQZ2	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3950\|UniProtKB=Q8P3W9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1045\|UniProtKB=Q9I4S9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0821\|UniProtKB=Q8ZQN7	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1206\|UniProtKB=A0A2S9PKW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35465\|UniProtKB=P27296	Escherichia coli	O
GEOSL\|EnsemblGenome=GSU0363\|UniProtKB=Q74G84	Geobacter sulfurreducens	O
HAEIN\|EnsemblGenome=HI_0387\|UniProtKB=P44680	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_2081\|UniProtKB=Q8EFA4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1990\|UniProtKB=Q9KQK8	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2930\|UniProtKB=Q8P6N7	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM1821\|UniProtKB=Q7CQD9	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2071\|UniProtKB=A0A3N4B3X5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA15617\|UniProtKB=P76257	Escherichia coli	O