PANTHER Gene Information

Gene Symbol(s):

sstr2

Organism:

Xenopus tropicalis

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Gene Name:

Somatostatin receptor type 2

Gene ID:

XB-GENE-953419

Protein ID:

A0A803JIC2

Persistent Id:

PTN008609944

Alternate Ids:

XP_002935929(refSeq)	512855475(GI)
ENSXETT00000117448(Ensembl_TRS)	A0A803JIC2_XENTR(UniProtKB-ID)
A0A803JIC2(Synonym)	ENSXETP00000111423(Ensembl_PRO)
ENSXETG00000045408(Ensembl)	100496382(GeneID)
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PANTHER Classification

PANTHER Family:	NEUROPEPTIDES RECEPTOR (PTHR24229)
PANTHER Subfamily:	SOMATOSTATIN RECEPTOR TYPE 2 (PTHR24229:SF6)
PANTHER GO-slim Molecular Function:	neuropeptide receptor activity neuropeptide binding
PANTHER GO-slim Biological Process:	response to estradiol cellular response to steroid hormone stimulus neuropeptide signaling pathway cellular response to oxygen-containing compound
PANTHER GO-slim Cellular Component:	plasma membrane neuron projection
PANTHER protein class:	G-protein coupled receptor

Pathway Categories:

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Gs-protein coupled receptor

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

Gi protein coupled receptor

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Go-protein coupled receptor

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	G protein-coupled receptor activity, neuropeptide binding, somatostatin receptor activity
GO BP Complete:	neuropeptide signaling pathway, cellular response to estradiol stimulus, G protein-coupled receptor signaling pathway, cellular response to glucocorticoid stimulus
GO CC Complete:	cytoplasm, membrane, neuron projection, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Signal Transduction, GPCR downstream signalling, G alpha (i) signalling events, Class A/1 (Rhodopsin-like receptors), Signaling by GPCR, Peptide ligand-binding receptors, GPCR ligand binding

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11331\|UniProtKB=P30874	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000043320.1\|UniProtKB=G2HFH4	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000051322.1\|UniProtKB=A0A5F8A2I1	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98328\|UniProtKB=P30875	Mus musculus	LDO
RAT\|RGD=3763\|UniProtKB=P30680	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017136.3\|UniProtKB=F1MEN6	Bos taurus	O
BOVIN\|Gene=SSTR2\|UniProtKB=P34993	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000021481.3\|UniProtKB=A0A9L0R3Q2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004735.5\|UniProtKB=M3W2Q8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020191.1\|UniProtKB=A0A8I3PBD4	Canis lupus familiaris	O
CANLF\|Gene=SSTR2\|UniProtKB=Q49LX6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000023942.1\|UniProtKB=F7F878	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004342.2\|UniProtKB=F6S3B9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029470.1\|UniProtKB=Q58G84	Gallus gallus	LDO
XENLA\|Gene=sstr2.L\|UniProtKB=Q6GQ36	Xenopus laevis	O
XENLA\|Gene=sstr2.S\|UniProtKB=A0A1L8EM69	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000007973.2\|UniProtKB=H2LV73	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-140130-1\|UniProtKB=E7FDL0	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-130530-727\|UniProtKB=E7F6Y6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017890.1\|UniProtKB=W5NMY4	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000017755.1\|UniProtKB=W5NMK0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000000406.3\|UniProtKB=F6SEF7	Ciona intestinalis	LDO
CIOIN\|Ensembl=ENSCING00000000234.3\|UniProtKB=F6T336	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000017497.2\|UniProtKB=F6T1G9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000014343.2\|UniProtKB=F6TZ58	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000019761.1\|UniProtKB=H2XU43	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000001757.2\|UniProtKB=F7AM41	Ciona intestinalis	LDO
CIOIN\|Ensembl=ENSCING00000001697.3\|UniProtKB=F6UJQ0	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426211\|UniProtKB=A0A9J7N659	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100894075\|UniProtKB=A0A7M7LVT1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918792\|UniProtKB=A0A7M7P664	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890211\|UniProtKB=A0A7M7GKD6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115922676\|UniProtKB=A0A7M7NQ32	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926735\|UniProtKB=A0A7M7T1W2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888551\|UniProtKB=A0A7M7NHJ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893852\|UniProtKB=A0A7M7GFS5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439709\|UniProtKB=A0A7M7N436	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578807\|UniProtKB=A0A7M7LVY3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918122\|UniProtKB=A0A7M7NM54	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC752674\|UniProtKB=A0A7M7HK66	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918536\|UniProtKB=A0A7M7NL69	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893370\|UniProtKB=A0A7M7HDG8	Strongylocentrotus purpuratus	O
DROME\|FlyBase=FBgn0266429\|UniProtKB=Q9U721	Drosophila melanogaster	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_60654\|UniProtKB=E9HB05	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG141773\|UniProtKB=T1EJ41	helobdella robusta	O
CAEEL\|WormBase=WBGene00008065\|UniProtKB=Q09502	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG16052\|UniProtKB=A8XN72	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00089848\|UniProtKB=A0A2A6BFS4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00006864\|UniProtKB=A0A3B1DQQ4	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034796\|UniProtKB=A8XJK0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00103481\|UniProtKB=A0A2A6CEY4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00010375\|UniProtKB=H9G358	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09656\|UniProtKB=A8X8J4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00273154\|UniProtKB=A0A2A6C5M8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008885\|UniProtKB=Q9XVQ0	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00277584\|UniProtKB=A0A2A6CGK0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00092761\|UniProtKB=A0A2A6BNC7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011372\|UniProtKB=A0A0K3AXD3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG00382\|UniProtKB=A8WMY5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00202780\|UniProtKB=A0A2A6BYV3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018886\|UniProtKB=Q20841	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041241\|UniProtKB=A8Y333	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00109898\|UniProtKB=A0A2A6CUK6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015559\|UniProtKB=P34311	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22950\|UniProtKB=A8Y3L2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00091461\|UniProtKB=A0A2A6CA63	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00204108\|UniProtKB=A0A2A6BQK5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00021328\|UniProtKB=Q9N452	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00040713\|UniProtKB=A8Y1H4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00094433\|UniProtKB=A0A2A6CEL5	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00018089\|UniProtKB=A0A2C9C3A4	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19271\|UniProtKB=A8XV84	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00107613\|UniProtKB=A0A2A6C5V7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00020086\|UniProtKB=Q23033	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00025042\|UniProtKB=A8WRG4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117000\|UniProtKB=A0A8R1UIE8	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0036260\|UniProtKB=Q9VTU7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007548\|UniProtKB=Q7QJJ6	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_346935\|UniProtKB=E9HBX2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_346930\|UniProtKB=E9HBW5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004568\|UniProtKB=B7PJM1	Ixodes scapularis	O
DROME\|FlyBase=FBgn0036790\|UniProtKB=Q9VVQ1	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0036789\|UniProtKB=A0A0S0WMT8	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010486\|UniProtKB=A0A1S4H448	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP012268\|UniProtKB=A0A1S4H9R6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002068\|UniProtKB=D7EIU6	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034475\|UniProtKB=A0A139WC60	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033099\|UniProtKB=A0A139WID0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC034476\|UniProtKB=A0A139WC11	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033098\|UniProtKB=A0A139WIL7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC011633\|UniProtKB=D6X0Z7	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC012842\|UniProtKB=D6X173	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_12571\|UniProtKB=E9H6K4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_12576\|UniProtKB=E9H6K3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW007666\|UniProtKB=B7PU05	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG181659\|UniProtKB=T1FH76	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82100\|UniProtKB=T1G4M7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG130073\|UniProtKB=T1EHT0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122299\|UniProtKB=T1EGU4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205366\|UniProtKB=A7S1I8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g224862\|UniProtKB=A7TBI0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246081\|UniProtKB=A7SLS4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214252\|UniProtKB=A7SLS3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209052\|UniProtKB=A7S9Z8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g222485\|UniProtKB=A7T577	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203549\|UniProtKB=A7RXC3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214208\|UniProtKB=A7SLN8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213211\|UniProtKB=A7SJG8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209053\|UniProtKB=A7S9Z9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200474\|UniProtKB=A7RQ77	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g209220\|UniProtKB=A7SAD6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221896\|UniProtKB=A7T3P5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246083\|UniProtKB=A7SLS6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g225244\|UniProtKB=A7TCH5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g207414\|UniProtKB=A7S662	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG60078\|UniProtKB=B3S787	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57575\|UniProtKB=B3RZT9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG56035\|UniProtKB=B3RTT0	Trichoplax adhaerens	O
BATDJ\|Gene_ORFName=BATDEDRAFT_86491\|UniProtKB=F4NXJ2	Batrachochytrium dendrobatidis	O