PANTHER Gene Information

Gene Symbol(s):

emc4

Organism:

Xenopus tropicalis

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Gene Name:

ER membrane protein complex subunit 4

Gene ID:

XB-GENE-965547

Protein ID:

Q6PBF7

Persistent Id:

PTN000448362

Alternate Ids:

XM_012958023(refSeq)	45360915(GI)
AAH59737(EMBL-CDS)	EMC4_XENTR(UniProtKB-ID)
emc4(Symbol)	BC059737(EMBL)
394471(GeneID)	Transmembrane protein 85(Synonym)
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PANTHER Classification

PANTHER Family:	ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 (PTHR19315)
PANTHER Subfamily:	ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 (PTHR19315:SF9)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	protein folding
PANTHER GO-slim Cellular Component:	EMC complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	membrane insertase activity
GO BP Complete:	protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tail-anchored membrane protein insertion into ER membrane
GO CC Complete:	endoplasmic reticulum membrane, membrane, EMC complex, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28032\|UniProtKB=Q5J8M3	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006878.5\|UniProtKB=H2Q938	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010931.3\|UniProtKB=A0A2I2ZU21	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012335.4\|UniProtKB=A0A5F8AS46	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915282\|UniProtKB=Q9CZX9	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000006416\|UniProtKB=Q3T0K8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039550.2\|UniProtKB=A0A286ZIA2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025049.4\|UniProtKB=A0A9L0SAD5	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000025049.4\|UniProtKB=A0A9L0SAD5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001736.5\|UniProtKB=M3VX67	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019980.1\|UniProtKB=A0A8I3PBW5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001665.4\|UniProtKB=F6SR81	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000015697.2\|UniProtKB=F7EP23	Ornithorhynchus anatinus	LDO
XENLA\|Gene=LOC108705001\|UniProtKB=A0A8J1M525	Xenopus laevis	O
XENLA\|Gene=emc4\|UniProtKB=Q6GR43	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000008954.2\|UniProtKB=H2LYK9	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024911.1\|UniProtKB=A0A3B3IEF0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1891\|UniProtKB=Q6P011	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000001928.3\|UniProtKB=A0A1W2W8Q4	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_126700\|UniProtKB=C3YFL5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580583\|UniProtKB=A0A7M7N6K0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022776\|UniProtKB=Q9N4N3	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00039069\|UniProtKB=A8XWS9	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0037199\|UniProtKB=Q9VNQ3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010558\|UniProtKB=Q7Q8U0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC016317\|UniProtKB=D6WMR9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_230984\|UniProtKB=E9GKX4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW006586\|UniProtKB=B7PMF9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG184819\|UniProtKB=T1FM17	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200413\|UniProtKB=A7RQ29	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63524\|UniProtKB=B3RM27	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_18332\|UniProtKB=A9UUF5	Monosiga brevicollis	LDO
YEAST\|SGD=S000003200\|UniProtKB=P53073	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR249W\|UniProtKB=Q753S7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000180939\|UniProtKB=A0A1D8PRI7	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A10274g\|UniProtKB=Q6CHC4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05951\|UniProtKB=Q5B0H9	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G10350\|UniProtKB=Q4X1D5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05231\|UniProtKB=Q7S8H7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_08463\|UniProtKB=A7ET08	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_13537\|UniProtKB=Q0U3X7	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC1281.03c\|UniProtKB=O94520	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02914\|UniProtKB=B6K1I4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA01770\|UniProtKB=Q5KPR9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11694\|UniProtKB=A0A0D1E3T9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_11004\|UniProtKB=E3KN39	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_06102\|UniProtKB=E3K5M8	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89618\|UniProtKB=F4P654	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=EHI_063570\|UniProtKB=C4MBJ2	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_012430\|UniProtKB=B1N2I5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0295773\|UniProtKB=C7FZZ9	Dictyostelium discoideum	LDO
LEIMA\|EnsemblGenome=LMJF_30_1625\|UniProtKB=Q4Q7D8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.6.2600\|UniProtKB=Q584P6	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1435400\|UniProtKB=Q8ILB0	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00016523001\|UniProtKB=A0DF93	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00007150001\|UniProtKB=A0CDS1	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_33995\|UniProtKB=B8C1D2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GTT9_PHYRM\|UniProtKB=H3GTT9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g351700v5\|UniProtKB=A0A2K3DLB9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00019p00068750\|UniProtKB=W1PHA9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_44G01330\|UniProtKB=A0A0K9P101	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g13180\|UniProtKB=A0A804IBJ2	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma07_g05420\|UniProtKB=A0A804JSG8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_037739mg\|UniProtKB=K4AFT2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G364600\|UniProtKB=C5WZL2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb394360\|UniProtKB=C0HHQ5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0360500\|UniProtKB=Q10L35	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g61820v3\|UniProtKB=I1H591	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0371810\|UniProtKB=A0A8I7B760	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G156600\|UniProtKB=A0A3B6JHL6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G138400\|UniProtKB=A0A1D5XTG1	Triticum aestivum	LDO
NELNU\|Gene=LOC104602144\|UniProtKB=A0A1U8A9F3	Nelumbo nucifera	O
NELNU\|Gene=LOC104589159\|UniProtKB=A0A1U7Z4I3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110802730\|UniProtKB=A0A9R0KAP4	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr07g0201211\|UniProtKB=A0A251UCU0	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0310381\|UniProtKB=A0A9K3INY4	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0542481\|UniProtKB=A0A251T3R6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800395610\|UniProtKB=A0A9R1WZY8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a014714mg\|UniProtKB=A0A022Q488	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a014736mg\|UniProtKB=A0A022QPH6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_31620\|UniProtKB=A0A1U8ER87	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400026285\|UniProtKB=M1CHJ9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g006650.3\|UniProtKB=A0A3Q7HK72	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107787939\|UniProtKB=A0A1S3ZKI5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107815857\|UniProtKB=A0A1S4C767	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi04g00619\|UniProtKB=A5BA14	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_C04036\|UniProtKB=A0A059CW99	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C02P04660.1\|UniProtKB=A0A078HTP4	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra028567\|UniProtKB=M4EIF2	Brassica campestris	O
BRACM\|EnsemblGenome=Bra006078\|UniProtKB=M4CPE0	Brassica campestris	LDO
ARATH\|TAIR=locus=2183745\|UniProtKB=A8MQD8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107906804\|UniProtKB=A0A1U8JGJ2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107958964\|UniProtKB=A0A1U8PGU3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107901650\|UniProtKB=A0A1U8IYR9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_036875\|UniProtKB=A0A061GIQ5	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g030270mg\|UniProtKB=A0A067FJ52	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_018G016800v3\|UniProtKB=A9PHF1	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_006G266300v3\|UniProtKB=B9HB78	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G007300\|UniProtKB=A0A2C9W4V3	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_16G131700\|UniProtKB=A0A2C9UCE2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0920530\|UniProtKB=B9RNT0	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_14G103800\|UniProtKB=I1M998	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G222100\|UniProtKB=A0A0R0FGT9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g013660\|UniProtKB=G7I7L8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr11_30450\|UniProtKB=A0A2I4G6N1	Juglans regia	O
JUGRE\|EnsemblGenome=Jr08_00680\|UniProtKB=A0A2I4FPT6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G651820\|UniProtKB=A0A0A0L0B6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G396200\|UniProtKB=M5XM02	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_168891\|UniProtKB=D8R7Z7	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_402529\|UniProtKB=D8QQY7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_15950\|UniProtKB=A9RDI8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0039s0015\|UniProtKB=A0A2R6X315	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003350070\|UniProtKB=A0A0U9HPB2	Klebsormidium nitens	LDO