PANTHER Gene Information

Gene Symbol(s):

PTC1

Organism:

Saccharomyces cerevisiae

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Gene Name:

Protein phosphatase 2C homolog 1

Gene ID:

S000002164

Protein ID:

P35182

Persistent Id:

PTN000353675

Alternate Ids:

YDL006W(Ensembl_PRO)	642800(GI)
PTC1(Symbol)	851558(GeneID)
3.1.3.16(EC)	S000002164(SGD)
NP_010278(refSeq)	YEAST:G3O-29437-MON(BioCyc)
D6VRY2(AltAccession)	PP2C1_YEAST(UniProtKB-ID)
CAA98562(EMBL-CDS)	BK006938(EMBL)
YDL006W_mRNA(Ensembl_TRS)	PP2C-1(Synonym)
YDL006W(Ensembl)
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PANTHER Classification

PANTHER Family:	PROTEIN PHOSPHATASE 2C (PTHR13832)
PANTHER Subfamily:	PROTEIN PHOSPHATASE 2C-LIKE DOMAIN-CONTAINING PROTEIN 1 (PTHR13832:SF837)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	protein dephosphorylation
PANTHER GO-slim Cellular Component:
PANTHER protein class:	protein phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	calmodulin-dependent protein phosphatase activity, cation binding, protein serine/threonine phosphatase activity, phosphoprotein phosphatase activity, protein binding, metal ion binding, RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity, RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity, MAP kinase serine/threonine phosphatase activity, histone H2AXS140 phosphatase activity, RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity, RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity, myosin phosphatase activity, RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity
GO BP Complete:	mitochondrion inheritance, chromatin remodeling, signal transduction, negative regulation of MAPK cascade, tRNA splicing, via endonucleolytic cleavage and ligation, fungal-type cell wall organization or biogenesis, pheromone-dependent signal transduction involved in conjugation with cellular fusion, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus, peroxisome, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28406\|UniProtKB=A8MPX8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014683.6\|UniProtKB=H2QM63	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012034.3\|UniProtKB=G3R8M0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006993.4\|UniProtKB=A0A1D5QVI2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3612067\|UniProtKB=Q8BVT6	Mus musculus	LDO
RAT\|RGD=1564811\|UniProtKB=D3ZZT7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004061.6\|UniProtKB=F1MDF9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005018689.1\|UniProtKB=A0A4X1UJS5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018679.4\|UniProtKB=A0A5F5PWI3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000040097.3\|UniProtKB=A0A2I2UN21	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021158.1\|UniProtKB=A0A8I3PFB6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014795.4\|UniProtKB=F7E6F4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004988.3\|UniProtKB=A0A6I8NXF7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010001770.1\|UniProtKB=A0A8V0XD10	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000016.4\|UniProtKB=G1KY53	Anolis carolinensis	LDO
XENLA\|Gene=LOC108719953\|UniProtKB=A0A8J0VQC2	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000038157\|UniProtKB=A0A6I8RT37	Xenopus tropicalis	LDO
LEPOC\|Ensembl=ENSLOCG00000006606.1\|UniProtKB=W5MHX0	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118405557\|UniProtKB=A0A9J7KJ11	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100893897\|UniProtKB=A0A7M7N171	Strongylocentrotus purpuratus	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g187597\|UniProtKB=A7SAI4	Nematostella vectensis	LDO
EREGS\|EnsemblGenome=AGOS_AEL010W\|UniProtKB=Q757M1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000194483\|UniProtKB=A0A1D8PEN6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D22066g\|UniProtKB=Q6C875	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06892\|UniProtKB=Q5AXT8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G13340\|UniProtKB=Q4WVU4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00434\|UniProtKB=Q7RXS5	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00528\|UniProtKB=A7E5F3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_10788\|UniProtKB=Q0UBS6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC4F11.02\|UniProtKB=P40371	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03185\|UniProtKB=B6K3J8	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA04830\|UniProtKB=Q5KNY9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01391\|UniProtKB=A0A0D1E7N1	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_06872\|UniProtKB=E3KA89	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_8550\|UniProtKB=F4NRI9	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0270176\|UniProtKB=Q55C81	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_74095\|UniProtKB=F0Z6W7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0284243\|UniProtKB=Q54PX6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_57785\|UniProtKB=F0ZXP6	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_34_2500\|UniProtKB=Q4Q2U6	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_34_2510\|UniProtKB=Q4Q2U5	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.4.2110\|UniProtKB=Q583I2	Trypanosoma brucei	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_262201\|UniProtKB=B8BZL0	Thalassiosira pseudonana	LDO
CHLAA\|EnsemblGenome=Caur_2654\|UniProtKB=A9WJF6	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_3816\|UniProtKB=A9WCN2	Chloroflexus aurantiacus	O
MYCTU\|Gene_OrderedLocusName=Rv0018c\|UniProtKB=P9WHW5	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_2513\|UniProtKB=Q9RRH8	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NP99_GLOVI\|UniProtKB=Q7NP99	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NKS2_GLOVI\|UniProtKB=Q7NKS2	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NGY0_GLOVI\|UniProtKB=Q7NGY0	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB8362\|UniProtKB=Q7UFS9	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_933\|UniProtKB=O67075	Aquifex aeolicus	O
BRADU\|Gene=Q89P80_BRADU\|UniProtKB=Q89P80	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC0989\|UniProtKB=Q8PBX6	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA0075\|UniProtKB=Q9I757	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA1670\|UniProtKB=Q9I355	Pseudomonas aeruginosa	O
CHLAA\|EnsemblGenome=Caur_1132\|UniProtKB=A9WJ85	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2667\|UniProtKB=Q9L254	Streptomyces coelicolor	O
MYCGE\|EnsemblGenome=MG_108\|UniProtKB=P47354	mycoplasma genitalium	O
CLOBH\|Gene_OrderedLocusName=CBO2505\|UniProtKB=A5I4T3	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1578\|UniProtKB=Q8DNR9	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01186\|UniProtKB=Q2FZ65	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99899\|UniProtKB=Q8Y678	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_15760\|UniProtKB=O34779	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3861\|UniProtKB=Q819U4	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_A0334\|UniProtKB=Q9RYH8	Deinococcus radiodurans	O
LEPIN\|EnsemblGenome=LA_1428\|UniProtKB=Q8F681	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_2772\|UniProtKB=Q8A432	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_259\|UniProtKB=O84261	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB3245\|UniProtKB=Q7UUK3	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_575\|UniProtKB=O66843	Aquifex aeolicus	O