PANTHER Gene Information

Gene Symbol(s):

MTR3

Organism:

Saccharomyces cerevisiae

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Gene Name:

Exosome complex component MTR3

Gene ID:

S000003390

Protein ID:

P48240

Persistent Id:

PTN000237420

Alternate Ids:

MTR3_YEAST(UniProtKB-ID)	906849227(GI)
NP_011674(refSeq)	D6VUT8(AltAccession)
853062(GeneID)	YEAST:G3O-30858-MON(BioCyc)
MTR3(Synonym)	YGR158C(Ensembl_PRO)
YGR158C_mRNA(Ensembl_TRS)	MTR3(Symbol)
DAA08249(EMBL-CDS)	BK006941(EMBL)
YGR158C(Ensembl)	S000003390(SGD)
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PANTHER Classification

PANTHER Family:	EXOSOME COMPLEX COMPONENT (PTHR11953)
PANTHER Subfamily:	EXOSOME COMPLEX COMPONENT MTR3 (PTHR11953:SF2)
PANTHER GO-slim Molecular Function:	RNA binding
PANTHER GO-slim Biological Process:	rRNA metabolic process snRNA 3'-end processing nuclear-transcribed mRNA catabolic process
PANTHER GO-slim Cellular Component:	exosome (RNase complex) nuclear protein-containing complex nucleolus cytoplasm
PANTHER protein class:	exoribonuclease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA binding, molecular_function
GO BP Complete:	poly(A)-dependent snoRNA 3'-end processing, U4 snRNA 3'-end processing, nuclear polyadenylation-dependent rRNA catabolic process, rRNA catabolic process, nuclear mRNA surveillance, nuclear polyadenylation-dependent CUT catabolic process, rRNA processing, TRAMP-dependent tRNA surveillance pathway, exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO CC Complete:	cytoplasmic exosome (RNase complex), nuclear exosome (RNase complex), nucleus, cytoplasm, nucleolus, exosome (RNase complex)

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA, Major pathway of rRNA processing in the nucleolus and cytosol, Deadenylation-dependent mRNA decay, mRNA decay by 3' to 5' exoribonuclease, rRNA processing in the nucleus and cytosol, rRNA processing, Regulation of mRNA stability by proteins that bind AU-rich elements, Metabolism of RNA, Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19055\|UniProtKB=Q5RKV6	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008296.3\|UniProtKB=H2QBF9	Pan troglodytes	LDO
MOUSE\|MGI=MGI=1919794\|UniProtKB=Q8BTW3	Mus musculus	LDO
RAT\|RGD=1309832\|UniProtKB=D3ZW38	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000053923.1\|UniProtKB=A8E4R4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000002719.4\|UniProtKB=F1S435	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000039860.2\|UniProtKB=A0A3Q2L3S5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000046021.1\|UniProtKB=A0A337SRG2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004932.1\|UniProtKB=A0A8I3MW71	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014523.3\|UniProtKB=F7ERN2	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010025438.1\|UniProtKB=A0A8V1A5A0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002802.3\|UniProtKB=A0A803SPE7	Anolis carolinensis	LDO
XENLA\|Gene=exosc6.L\|UniProtKB=A0A1L8GLH9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-998313\|UniProtKB=Q28F19	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000013325.2\|UniProtKB=H2MDQ1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050522-362\|UniProtKB=Q6P0I8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017597.1\|UniProtKB=W5NM43	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000013458.2\|UniProtKB=F6V2B2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118405079\|UniProtKB=A0A9J7HLH9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584729\|UniProtKB=A0A7M7STL8	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0036916\|UniProtKB=Q9VW53	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP011906\|UniProtKB=Q5TMQ4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008865\|UniProtKB=D6WQR6	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_340646\|UniProtKB=E9I4I1	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_50975\|UniProtKB=E9GIE3	Daphnia pulex	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g180736\|UniProtKB=A7RQ94	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG61054\|UniProtKB=B3S9X0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_23837\|UniProtKB=A9UUZ6	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AFR109W\|UniProtKB=Q754G1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000191642\|UniProtKB=A0A1D8PS88	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E06039g\|UniProtKB=Q6C6V0	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02153\|UniProtKB=Q5BBC7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G15980\|UniProtKB=Q4WZS0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08026\|UniProtKB=Q7SAL5	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_08471\|UniProtKB=A7ET16	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_08517\|UniProtKB=Q0UI97	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC211.08c\|UniProtKB=Q9P7R3	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00854\|UniProtKB=B6JWS8	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNJ02640\|UniProtKB=Q5KA82	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04549\|UniProtKB=A0A0D1DUL7	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_18371\|UniProtKB=E3L761	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_10390\|UniProtKB=E3KKU4	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_84610\|UniProtKB=F4NT56	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_126330\|UniProtKB=C4LW17	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0271396\|UniProtKB=Q55BB0	Dictyostelium discoideum	LDO
LEIMA\|EnsemblGenome=LMJF_36_4895\|UniProtKB=Q4Q0S3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.2820\|UniProtKB=Q383H5	Trypanosoma brucei	LDO
PHYRM\|Gene=H3GV34_PHYRM\|UniProtKB=H3GV34	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_17g697624v5\|UniProtKB=A0A2K3CNP3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00148p00071740\|UniProtKB=W1PKV6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_86G00270\|UniProtKB=A0A0K9NMT7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g23820\|UniProtKB=A0A804I677	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_030850mg\|UniProtKB=K3ZW68	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G386300\|UniProtKB=C5X376	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb328370\|UniProtKB=A0A1D6IKI0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os08g0116800\|UniProtKB=Q69UI6	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os03g0844450\|UniProtKB=Q75LC8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g20450v3\|UniProtKB=I1GS12	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0122110\|UniProtKB=A0A8I7B5A0	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2A02G156200\|UniProtKB=A0A3B6AUV0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G181700\|UniProtKB=W5BNF8	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_027675\|UniProtKB=A0A1U7ZPE2	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110802152\|UniProtKB=A0A9R0K970	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0656581\|UniProtKB=A0A251SJS9	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200086250\|UniProtKB=A0A9R1WFQ2	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a012266mg\|UniProtKB=A0A022PTF0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_02231\|UniProtKB=A0A1U8H694	Capsicum annuum	LDO
CAPAN\|EnsemblGenome=T459_16247\|UniProtKB=A0A2G2Z8J9	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_15908\|UniProtKB=A0A2G2Z772	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400020831\|UniProtKB=M1BVC8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc06g005860.2\|UniProtKB=A0A3Q7HIP1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107827829\|UniProtKB=A0A1S4DAV3	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107816340\|UniProtKB=A0A1S4C8R0	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi06g00261\|UniProtKB=A5BI33	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J00908\|UniProtKB=A0A059ACJ5	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00019425001\|UniProtKB=A0A078J2F6	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C01P23670.1\|UniProtKB=A0A078GW08	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra026344\|UniProtKB=M4EC35	Brassica campestris	LDO
ARATH\|TAIR=locus=2124024\|UniProtKB=A2RVK7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107959013\|UniProtKB=A0A1U8PJH0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107906248\|UniProtKB=A0A1U8JEH3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_042083\|UniProtKB=A0A061GX12	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_004G212500v3\|UniProtKB=U5GGW3	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_009G010600v3\|UniProtKB=B9HQC2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_04G018600\|UniProtKB=A0A2C9W043	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0033810\|UniProtKB=B9SVB2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G145000\|UniProtKB=I1LL42	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_12G076900\|UniProtKB=I1LR48	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g058720\|UniProtKB=G7JND2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr05_10150\|UniProtKB=A0A2I4GK75	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G146430\|UniProtKB=A0A0A0KEK6	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G104100\|UniProtKB=A0A251NN69	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_6G104200\|UniProtKB=M5WCF1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_441621\|UniProtKB=D8RL35	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_80529\|UniProtKB=D8QWZ7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_18310\|UniProtKB=A0A2K1KUY7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0055s0093\|UniProtKB=A0A2R6WVH3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_008730020\|UniProtKB=A0A1Y1IM48	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0432\|UniProtKB=A9A5C9	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1370\|UniProtKB=B1L6N7	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0735\|UniProtKB=Q9UXC2	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE2207\|UniProtKB=Q8ZVM9	Pyrobaculum aerophilum	O
THEKO\|EnsemblGenome=TK1634\|UniProtKB=Q5JIR6	Thermococcus kodakaraensis	O
CHLAA\|EnsemblGenome=Caur_0245\|UniProtKB=A9WCA5	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2904\|UniProtKB=Q9S2H7	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1340\|UniProtKB=P9WGZ7	Mycobacterium tuberculosis	O
LISMO\|EnsemblGenome=CAC99316\|UniProtKB=Q8Y7N6	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_28370\|UniProtKB=P28619	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4494\|UniProtKB=Q817P3	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_1585\|UniProtKB=Q9RU11	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB5725\|UniProtKB=Q7URE2	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_924\|UniProtKB=O67069	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A1385\|UniProtKB=B5YFY8	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1338\|UniProtKB=B8E0G7	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1851\|UniProtKB=Q8RHY9	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB1499\|UniProtKB=Q9JYN5	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1795\|UniProtKB=Q74C79	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC45939\|UniProtKB=Q89WK4	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0299\|UniProtKB=Q83EL9	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0273\|UniProtKB=P44444	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_4256\|UniProtKB=Q8E9L4	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0210\|UniProtKB=Q9KVD6	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3251\|UniProtKB=Q8P5T5	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA5334\|UniProtKB=P50597	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3734\|UniProtKB=P0A2C3	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0045\|UniProtKB=Q8ZJP8	Yersinia pestis	O
ECOLI\|EnsemblGenome=b3643\|UniProtKB=P0CG19	Escherichia coli	O