PANTHER Gene Information

Gene Symbol(s):

Organism:

Anopheles gambiae

View Gene in Tree


Tree	Reduced Tree

Gene Name:

Phosphatidylinositol-4-phosphate 3-kinase

Gene ID:

AGAP011036

Protein ID:

A0A1S4H5J3

Persistent Id:

PTN000005742

Alternate Ids:

AGAP011036-PA(Ensembl_PRO)	AAAB01008804(EMBL)
A0A1S4H5J3(Synonym)	A0A1S4H5J3_ANOGA(UniProtKB-ID)
AGAP011036(Ensembl)	AGAP011036-RA(Ensembl_TRS)
Show All

PANTHER Classification

PANTHER Family:	PHOSPHATIDYLINOSITOL KINASE (PTHR10048)
PANTHER Subfamily:	LD28067P (PTHR10048:SF14)
PANTHER GO-slim Molecular Function:	lipid kinase activity phosphotransferase activity, alcohol group as acceptor
PANTHER GO-slim Biological Process:	cell migration phosphatidylinositol phosphate biosynthetic process phosphatidylinositol 3-kinase/protein kinase B signal transduction
PANTHER GO-slim Cellular Component:	phosphatidylinositol 3-kinase complex plasma membrane cytoplasm
PANTHER protein class:	kinase

Pathway Categories:

VEGF signaling pathway

Phosphatidylinositol 3-kinase

Ras Pathway

Phosphatidylinositol 3-kinase

Hypoxia response via HIF activation

Phosphatidylinositol 3-kinase

Insulin/IGF pathway-protein kinase B signaling cascade

Phosphatidylinositol 3-kinase

Inflammation mediated by chemokine and cytokine signaling pathway

Phosphatidylinositol 3-kinase

FGF signaling pathway

Phosphatidylinositol 3-kinase

Angiogenesis

Phosphatidylinositol 3-kinase

EGF receptor signaling pathway

Phosphatidylinositol 3-kinase

Integrin signalling pathway

Phosphatidylinositol 3-kinase

Axon guidance mediated by netrin

Phosphatidylinositol 3-kinase

PDGF signaling pathway

Phosphatidylinositol 3-kinase

Endothelin signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway feedback loops 2

Phosphatidylinositol 3-kinase

Apoptosis signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway

Phosphatidylinositol 3-kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, phosphatidylinositol binding, kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, 1-phosphatidylinositol-3-kinase activity
GO BP Complete:	phosphatidylinositol 3-kinase/protein kinase B signal transduction, phosphatidylinositol-mediated signaling, lipid metabolic process, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol phosphate biosynthetic process, cell migration
GO CC Complete:	cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8971\|UniProtKB=O00443	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003399.5\|UniProtKB=H2Q383	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011040.3\|UniProtKB=G3RRS8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022548.4\|UniProtKB=F6Y9J9	Macaca mulatta	O
MOUSE\|MGI=MGI=1203729\|UniProtKB=Q61194	Mus musculus	O
RAT\|RGD=1310389\|UniProtKB=D3ZTF6	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004901.6\|UniProtKB=E1BE68	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000025406.3\|UniProtKB=I3LLX2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014963.4\|UniProtKB=F6U9E2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023161.4\|UniProtKB=A0A2I2UT47	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845027085.1\|UniProtKB=A0A8I3SAR3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000007062.5\|UniProtKB=F6PV08	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007685.3\|UniProtKB=F6VDD2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010023209.1\|UniProtKB=A0A8V0ZLS9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000045.4\|UniProtKB=G1K875	Anolis carolinensis	O
XENLA\|Gene=pik3c2a.S\|UniProtKB=A0A1L8GEH2	Xenopus laevis	O
XENLA\|Gene=pik3c2a.L\|UniProtKB=A0A1L8GIB5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-484563\|UniProtKB=F6SUB4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000001292.2\|UniProtKB=A0A3B3IHY8	Oryzias latipes	O
DANRE\|Gene=pik3c2a\|UniProtKB=A0A8M2B5U1	Danio rerio	O
DANRE\|Ensembl=ENSDARG00000109612.1\|UniProtKB=A0A2R8QSP1	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002963.1\|UniProtKB=W5M537	lepisosteus oculatus	O
HUMAN\|HGNC=8973\|UniProtKB=O75747	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004741.5\|UniProtKB=A0A2J8QPU6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000017159.3\|UniProtKB=G3RLT6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022174.4\|UniProtKB=F6XHZ4	Macaca mulatta	O
MOUSE\|MGI=MGI=1203730\|UniProtKB=O70167	Mus musculus	O
RAT\|RGD=620231\|UniProtKB=O70173	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020715.6\|UniProtKB=E1B8D1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000591.5\|UniProtKB=A0A5K1VBK6	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000000247.6\|UniProtKB=M3VUD0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018749.1\|UniProtKB=A0A8I3NWP1	Canis lupus familiaris	O
CHICK\|Ensembl=ENSGALG00010013617.1\|UniProtKB=A0A8V0YN62	Gallus gallus	O
XENLA\|Gene=LOC108712508\|UniProtKB=A0A1L8GQ56	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000045201\|UniProtKB=A0A803KDN3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000029595.1\|UniProtKB=A0A3B3H7C6	Oryzias latipes	O
DANRE\|Gene=pik3c2g\|UniProtKB=A0A8M6Z287	Danio rerio	O
HUMAN\|HGNC=8972\|UniProtKB=O00750	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001888.6\|UniProtKB=K7D8P6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000001355.3\|UniProtKB=G3QG89	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016563.4\|UniProtKB=H9ESL7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2685045\|UniProtKB=E9QAN8	Mus musculus	LDO
RAT\|RGD=1306541\|UniProtKB=A0A0G2K1Q0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000024633.6\|UniProtKB=F1MBU9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000015283.5\|UniProtKB=F1S374	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000015106.4\|UniProtKB=A0A3Q2ILC5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014850.6\|UniProtKB=M3WLG8	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023047.1\|UniProtKB=A0A8I3PM55	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001583.4\|UniProtKB=F7BBM1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013462.3\|UniProtKB=F7FB55	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027372.1\|UniProtKB=A0A1D5PQ64	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007419.3\|UniProtKB=G1KGS9	Anolis carolinensis	LDO
XENTR\|Gene=pik3c2b\|UniProtKB=A0A8J1J4B3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010776.2\|UniProtKB=H2M4Z3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050309-145\|UniProtKB=F1QWN6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012102.1\|UniProtKB=W5N2P3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023383.1\|UniProtKB=H2Y1I5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414477\|UniProtKB=A0A9J7L1K4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586734\|UniProtKB=A0A7M7P313	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009552\|UniProtKB=G5EDY0	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG07670\|UniProtKB=A8X4B6	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00095713\|UniProtKB=A0A2A6BJJ3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015278\|UniProtKB=Q7K3H0	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC034925\|UniProtKB=A0A139WAA5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303261\|UniProtKB=E9FU84	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004026\|UniProtKB=B7PIF4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022811\|UniProtKB=B7QET6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90881\|UniProtKB=A7RRA6	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28086\|UniProtKB=A9V757	Monosiga brevicollis	LDO
ENTH1\|EnsemblGenome=EHI_188970\|UniProtKB=C4M2W4	Entamoeba histolytica	LDO
ENTH1\|EnsemblGenome=CL6EHI_006130\|UniProtKB=C4M2P7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_095130\|UniProtKB=C4M4S6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_040690\|UniProtKB=C4M5P0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_009890\|UniProtKB=C4M0Q4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_013980\|UniProtKB=C4LXN9	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0268548\|UniProtKB=Q55FX5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38568\|UniProtKB=F0ZUR5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0291093\|UniProtKB=Q54F55	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_96754\|UniProtKB=F0ZAX6	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0283081\|UniProtKB=P54674	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_52203\|UniProtKB=F0Z7E7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282625\|UniProtKB=Q54S78	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_35373\|UniProtKB=F0ZP96	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0275011\|UniProtKB=P54675	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149892\|UniProtKB=F0ZEX7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0278727\|UniProtKB=P54673	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_58194\|UniProtKB=F0ZZM8	Dictyostelium purpureum	LDO
GIAIC\|EnsemblGenome=GL50803_14855\|UniProtKB=A8B5J3	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_393100\|UniProtKB=A2DYA6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_344900\|UniProtKB=A2F0T8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_083340\|UniProtKB=A2DM61	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_284350\|UniProtKB=A2EN93	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_101460\|UniProtKB=A2DJM8	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00018694001\|UniProtKB=A0DN72	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00019938001\|UniProtKB=A0DT78	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012877001\|UniProtKB=A0D2V1	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00027505001\|UniProtKB=A0EIN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039649001\|UniProtKB=A0DLV0	Paramecium tetraurelia	O
PHYRM\|Gene=H3GL97_PHYRM\|UniProtKB=H3GL97	Phytophthora ramorum	LDO
PHYRM\|Gene=H3GLA1_PHYRM\|UniProtKB=H3GLA1	Phytophthora ramorum	O
KLENI\|Gene_ORFName=KFL_003910060\|UniProtKB=A0A1Y1IAN1	Klebsormidium nitens	LDO