PANTHER Gene Information

Gene Symbol(s):

FGF1

Organism:

Pan troglodytes

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Gene Name:

Multifunctional fusion protein

Gene ID:

ENSPTRG00000017361.7

Protein ID:

A0A2J8NIY5

Persistent Id:

PTN000160310

Alternate Ids:

AC183921(EMBL)	XM_001153676(refSeq)
1034170952(GI)	A0A2J8NIY5_PANTR(UniProtKB-ID)
VDK10848(EMBL-CDS)	ENSPTRG00000017361(Ensembl)
ENSPTRT00000032123(Ensembl_TRS)	A0A2J8NIY5(Synonym)
462158(GeneID)	ENSPTRP00000029676(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily:	FIBROBLAST GROWTH FACTOR 1 (PTHR11486:SF86)
PANTHER GO-slim Molecular Function:	growth factor activity fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process:	regulation of cell migration fibroblast growth factor receptor signaling pathway cell differentiation positive regulation of protein serine/threonine kinase activity positive regulation of MAPK cascade positive regulation of gene expression positive regulation of cell population proliferation animal organ morphogenesis regulation of MAP kinase activity
PANTHER GO-slim Cellular Component:	extracellular space nucleus cytoplasm
PANTHER protein class:	growth factor

Pathway Categories:

Angiogenesis

Fibroblast Growth Factor

FGF signaling pathway

fibroblast growth factor

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	growth factor activity, integrin binding, heparin binding, S100 protein binding, fibroblast growth factor receptor binding
GO BP Complete:	positive regulation of cell population proliferation, branch elongation involved in ureteric bud branching, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of cholesterol biosynthetic process, positive regulation of intracellular signal transduction, positive regulation of transcription by RNA polymerase II, positive regulation of angiogenesis, wound healing, mesonephric epithelium development, cellular response to heat, epithelial cell proliferation, positive regulation of cell division, angiogenesis, positive regulation of endothelial cell migration, positive regulation of epithelial cell proliferation, lung development, signal transduction, positive regulation of sprouting angiogenesis, positive regulation of MAPK cascade, regulation of endothelial tube morphogenesis, positive regulation of ERK1 and ERK2 cascade, organ induction, cell differentiation, regulation of endothelial cell chemotaxis to fibroblast growth factor, regulation of cell migration, positive regulation of cell migration
GO CC Complete:	nucleus, extracellular space, cytoplasm, cell cortex, cytosol, extracellular matrix, extracellular region, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3665\|UniProtKB=P05230	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000025578.2\|UniProtKB=G3RPE3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000057828.1\|UniProtKB=F7E243	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95515\|UniProtKB=P61148	Mus musculus	LDO
RAT\|RGD=2605\|UniProtKB=P61149	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005198\|UniProtKB=P03968	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000024954.4\|UniProtKB=F1RM38	Sus scrofa	LDO
PIG\|Gene=FGF1\|UniProtKB=P20002	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020769.4\|UniProtKB=A0A9L0TQU2	Equus caballus	LDO
HORSE\|Ensembl=ENSECAG00000020769.4\|UniProtKB=A0A9L0TQU2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000035589.3\|UniProtKB=A0A2I2U4K4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845017942.1\|UniProtKB=A0A8I3NV07	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000029105.2\|UniProtKB=A0A5F8GN80	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010013399\|UniProtKB=P19596	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000043127.1\|UniProtKB=A0A803SLR7	Anolis carolinensis	LDO
XENLA\|Gene=fgf1.L\|UniProtKB=A0A1L8GXF9	Xenopus laevis	O
XENLA\|Gene=fgf1\|UniProtKB=Q6GLR6	Xenopus laevis	O
XENLA\|Gene=fgf1.S\|UniProtKB=A0A1L8GVD8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-485966\|UniProtKB=F6XSB5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000001499.2\|UniProtKB=H2L7N5	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000006013.2\|UniProtKB=H2LND4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-071004-7\|UniProtKB=A7YT71	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1729\|UniProtKB=Q6PBT8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010543.1\|UniProtKB=W5MX08	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023485.1\|UniProtKB=H2XNQ4	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_117174\|UniProtKB=C3XW39	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00002881\|UniProtKB=Q11184	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19663\|UniProtKB=A8XW48	Caenorhabditis briggsae	LDO
TRICA\|EnsemblGenome=TC034131\|UniProtKB=A0A139WCW4	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW009091\|UniProtKB=B7PXH9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212165\|UniProtKB=A7SH09	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g244903\|UniProtKB=A7SFH7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196402\|UniProtKB=A7RFG7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247007\|UniProtKB=A7SRV4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g217516\|UniProtKB=A7SU37	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211797\|UniProtKB=A7SG69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212596\|UniProtKB=A7SI24	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g16985\|UniProtKB=A7SI25	Nematostella vectensis	LDO