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Gene Symbol(s):
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PIK3R2
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| Organism: |
Canis lupus familiaris |
| View Gene in Tree |
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| Gene Name: |
Phosphoinositide-3-kinase regulatory subunit 2
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| Gene ID: |
ENSCAFG00845023471.1
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| Protein ID: |
A0A8I3S3N2
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| Persistent Id: |
PTN000016409 |
| Alternate Ids: |
| XP_852406(refSeq) |
A0A8I3S3N2_CANLF(UniProtKB-ID) |
| ENSCAFP00845032484(Ensembl_PRO) |
345787028(GI) |
| A0A8I3S3N2(Synonym) |
ENSCAFT00845041427(Ensembl_TRS) |
| ENSCAFG00845023471(Ensembl) |
609956(GeneID) |
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Show All
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| GO MF Complete: |
phosphotyrosine residue binding, protein phosphatase binding, phosphatidylinositol 3-kinase regulatory subunit binding, protein heterodimerization activity, receptor tyrosine kinase binding, 1-phosphatidylinositol-3-kinase regulator activity
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| GO BP Complete: |
regulation of actin filament polymerization, regulation of protein localization to plasma membrane, positive regulation of protein import into nucleus, phosphatidylinositol 3-kinase/protein kinase B signal transduction, intracellular glucose homeostasis, insulin receptor signaling pathway, negative regulation of MAPK cascade, regulation of autophagy, regulation of stress fiber assembly, positive regulation of cell adhesion, positive regulation of transcription by RNA polymerase II, response to endoplasmic reticulum stress
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| GO CC Complete: |
phosphatidylinositol 3-kinase complex, class IA, nucleus, focal adhesion
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| Reactome Pathways: |
PI3K Cascade, Interleukin-3, Interleukin-5 and GM-CSF signaling, Signaling by Interleukins, RHOF GTPase cycle, Insulin receptor signalling cascade, IRS-related events triggered by IGF1R, Signaling by Insulin receptor, Interleukin-7 signaling, IGF1R signaling cascade, CD28 dependent PI3K/Akt signaling, CD28 co-stimulation, RHOA GTPase cycle, RND3 GTPase cycle, Signaling by VEGF, Signaling by NTRK1 (TRKA), Interleukin receptor SHC signaling, Synthesis of PIPs at the plasma membrane, RHOJ GTPase cycle, RAC2 GTPase cycle, Signaling by GPCR, RHOD GTPase cycle, MAPK1/MAPK3 signaling, RHO GTPase cycle, Role of LAT2/NTAL/LAB on calcium mobilization, Developmental Biology, DAP12 signaling, IRS-mediated signalling, Extra-nuclear estrogen signaling, Signaling by SCF-KIT, Tie2 Signaling, VEGFA-VEGFR2 Pathway, Axon guidance, Metabolism of lipids, Fcgamma receptor (FCGR) dependent phagocytosis, Downstream TCR signaling, Signal Transduction, Innate Immune System, PIP3 activates AKT signaling, Intracellular signaling by second messengers, Regulation of signaling by CBL, Metabolism, PI Metabolism, Phospholipid metabolism, RHOU GTPase cycle, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Costimulation by the CD28 family, Nervous system development, RAF/MAP kinase cascade, Role of phospholipids in phagocytosis, Signaling by Nuclear Receptors, G alpha (q) signalling events, Cell surface interactions at the vascular wall, Signaling by Rho GTPases, Signaling by Receptor Tyrosine Kinases, Immune System, Interleukin-2 family signaling, Downstream signal transduction, DAP12 interactions, RHOB GTPase cycle, RAC1 GTPase cycle, RAC3 GTPase cycle, CDC42 GTPase cycle, ESR-mediated signaling, GPCR downstream signalling, Fc epsilon receptor (FCERI) signaling, GPVI-mediated activation cascade, PI3K/AKT activation, Signaling by PDGF, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Platelet activation, signaling and aggregation, Adaptive Immune System, Signaling by NTRKs, TCR signaling, RET signaling, Cytokine Signaling in Immune system, Hemostasis, RND1 GTPase cycle, Signaling by ALK, RND2 GTPase cycle, Negative regulation of the PI3K/AKT network, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), MAPK family signaling cascades
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