PANTHER Gene Information   
Gene Symbol(s): PRKAR2B
Organism: Canis lupus familiaris
View Gene in Tree
Tree
Tree
Gene Name: Protein kinase cAMP-dependent type II regulatory subunit beta
Gene ID: ENSCAFG00845026498.1
Protein ID: A0A8I3S5Y6
Persistent Id: PTN000180647
Alternate Ids:
ENSCAFG00845026498(Ensembl) ENSCAFT00845046898(Ensembl_TRS)
A0A8I3S5Y6(Synonym) A0A8I3S5Y6_CANLF(UniProtKB-ID)
ENSCAFP00845036783(Ensembl_PRO)
Show All

PANTHER Classification
PANTHER Family: CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN (PTHR11635)
PANTHER Subfamily: CAMP-DEPENDENT PROTEIN KINASE TYPE II-BETA REGULATORY SUBUNIT (PTHR11635:SF156)  
PANTHER GO-slim Molecular Function: protein kinase binding
protein kinase A binding
protein kinase inhibitor activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: regulation of protein serine/threonine kinase activity
negative regulation of protein kinase activity
PANTHER GO-slim Cellular Component: serine/threonine protein kinase complex
intracellular protein-containing complex
cytosol
PANTHER protein class: kinase modulator
Pathway Categories: Metabotropic glutamate receptor group II pathway
   Protein kinase A
GABA-B receptor II signaling
   Protein kinase A
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
   Protein kinase A
Transcription regulation by bZIP transcription factor
   Protein kinase A
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Protein kinase A, regulatory subunit
Endothelin signaling pathway
   Protein kinase A
Enkephalin release
   Protein kinase A
Beta1 adrenergic receptor signaling pathway
   Protein kinase A
Hedgehog signaling pathway
   Protein kinase A
Dopamine receptor mediated signaling pathway
   Protein kinase A
5HT1 type receptor mediated signaling pathway
   Protein kinase A
Metabotropic glutamate receptor group III pathway
   Protein kinase A
Histamine H2 receptor mediated signaling pathway
   Protein kinase A
Beta2 adrenergic receptor signaling pathway
   Protein kinase A
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein kinase A catalytic subunit binding, cAMP binding, cAMP-dependent protein kinase regulator activity, cAMP-dependent protein kinase inhibitor activity
GO BP Complete: adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO CC Complete: cytosol, cAMP-dependent protein kinase complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: DAG and IP3 signaling, Neuronal System, G alpha (s) signalling events, Cilium Assembly, AURKA Activation by TPX2, Signaling by GPCR, Transmission across Chemical Synapses, Organelle biogenesis and maintenance, Neurotransmitter receptors and postsynaptic signal transmission, G2/M Transition, Cell Cycle, Mitotic, CaM pathway, G alpha (i) signalling events, Mitotic G2-G2/M phases, Post NMDA receptor activation events, Anchoring of the basal body to the plasma membrane, Glucagon signaling in metabolic regulation, Transport of small molecules, Signal Transduction, G-protein mediated events, Activation of NMDA receptors and postsynaptic events, PLC beta mediated events, Loss of Nlp from mitotic centrosomes, Intracellular signaling by second messengers, Ca-dependent events, Metabolism, DARPP-32 events, Loss of proteins required for interphase microtubule organization from the centrosome, Aquaporin-mediated transport, Recruitment of NuMA to mitotic centrosomes, Centrosome maturation, CREB1 phosphorylation through the activation of Adenylate Cyclase, PKA activation in glucagon signalling, Vasopressin regulates renal water homeostasis via Aquaporins, Integration of energy metabolism, Opioid Signalling, Hedgehog 'off' state, M Phase, GPCR downstream signalling, PKA-mediated phosphorylation of CREB, Calmodulin induced events, Signaling by Hedgehog, PKA activation, Recruitment of mitotic centrosome proteins and complexes, GPER1 signaling, Hemostasis, Factors involved in megakaryocyte development and platelet production, Regulation of PLK1 Activity at G2/M Transition, Mitotic Prometaphase, Cell Cycle

Orthologs