PANTHER Gene Information

Gene Symbol(s):

QARS1

Organism:

Canis lupus familiaris

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Gene Name:

glutamine--tRNA ligase

Gene ID:

ENSCAFG00845029059.1

Protein ID:

A0A8I3S702

Persistent Id:

PTN000012647

Alternate Ids:

ENSCAFG00845029059(Ensembl)	A0A8I3S702(Synonym)
ENSCAFP00845040351(Ensembl_PRO)	ENSCAFT00845051433(Ensembl_TRS)
A0A8I3S702_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	GLUTAMINE-TRNA LIGASE (PTHR43097)
PANTHER Subfamily:	GLUTAMINE--TRNA LIGASE (PTHR43097:SF4)
PANTHER GO-slim Molecular Function:	catalytic activity, acting on RNA ligase activity
PANTHER GO-slim Biological Process:	amino acid metabolic process translation tRNA metabolic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	aminoacyl-tRNA synthetase

Pathway Categories:

Heme biosynthesis

Glutamyl-tRNA-synthetase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, protein kinase binding, glutamine-tRNA ligase activity, protein kinase inhibitor activity
GO BP Complete:	negative regulation of DNA-templated transcription, negative regulation of stress-activated MAPK cascade, brain development, glutaminyl-tRNA aminoacylation, negative regulation of apoptotic signaling pathway
GO CC Complete:	cytosol, aminoacyl-tRNA synthetase multienzyme complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9751\|UniProtKB=P47897	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014910.5\|UniProtKB=K7DIB3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014882.3\|UniProtKB=A0A2I2YFY2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002943.4\|UniProtKB=A0A1D5QZV5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1915851\|UniProtKB=Q8BML9	Mus musculus	LDO
RAT\|RGD=1359448\|UniProtKB=Q66H61	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000018928\|UniProtKB=Q3MHH4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005045271.1\|UniProtKB=M3TYW5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000000809.4\|UniProtKB=F6WN90	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009846.5\|UniProtKB=A0A2I2UCN5	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000013321.4\|UniProtKB=F7GJG2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014118.4\|UniProtKB=F6VM76	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020619.1\|UniProtKB=A0A8V0ZF10	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012645.4\|UniProtKB=A0A803SQM8	Anolis carolinensis	LDO
XENLA\|Gene=qars1.S\|UniProtKB=Q6PF26	Xenopus laevis	O
XENLA\|Gene=qars1.L\|UniProtKB=A0A1L8GQ05	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000010737.2\|UniProtKB=H2M4U8	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000014502.1\|UniProtKB=W5NB53	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009130.4\|UniProtKB=F6S399	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118415915\|UniProtKB=A0A9J7MR82	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105439088\|UniProtKB=A0A7M7N1Y5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC580092\|UniProtKB=A0A7M7MXM1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001336\|UniProtKB=O62431	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00034482\|UniProtKB=A8XIN7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00272314\|UniProtKB=A0A2A6BYL4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0027090\|UniProtKB=Q9Y105	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010267\|UniProtKB=Q7Q0M3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000042\|UniProtKB=D6WDE3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_247550\|UniProtKB=E9GSP0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_307141\|UniProtKB=E9FZJ3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW000777\|UniProtKB=B7P5X4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG63797\|UniProtKB=T1FXK3	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g167786\|UniProtKB=A7S8N2	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG37025\|UniProtKB=B3RIA1	Trichoplax adhaerens	LDO
YEAST\|SGD=S000005694\|UniProtKB=P13188	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR259C\|UniProtKB=Q74ZE0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000198388\|UniProtKB=A0A1D8PQM9	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C03674g\|UniProtKB=Q6CD53	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_09157\|UniProtKB=Q5ARC3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G01920\|UniProtKB=Q4WIG6	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07926\|UniProtKB=Q7S9Z2	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_13818\|UniProtKB=A7F887	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_05848\|UniProtKB=Q0UQW6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC342.02\|UniProtKB=Q9Y7Y8	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04482\|UniProtKB=B6K6Y2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA00740\|UniProtKB=Q5KQ22	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05125\|UniProtKB=A0A0D1E2G3	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_86970\|UniProtKB=F4NXW0	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_062700\|UniProtKB=C4M1P6	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0289481\|UniProtKB=P14325	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_57084\|UniProtKB=F0ZU88	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_15_1440\|UniProtKB=Q4QF36	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.160.3730\|UniProtKB=Q38F32	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_9348\|UniProtKB=A8BT15	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_258380\|UniProtKB=A2E942	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1331700\|UniProtKB=Q8IE10	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00017847001\|UniProtKB=A0DKF1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032125001\|UniProtKB=A0BTM6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035088001\|UniProtKB=A0C491	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_13806\|UniProtKB=B8C444	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_260900\|UniProtKB=B8BQK8	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_14g614900v5\|UniProtKB=A0A2K3CXL9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00006p00246940\|UniProtKB=W1PDP3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_24G00290\|UniProtKB=A0A0K9PGA4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g05540\|UniProtKB=A0A804HQM2	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma06_g25920\|UniProtKB=A0A804JKG9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_021257mg\|UniProtKB=K3Z3Y9	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3009G068700\|UniProtKB=C5YU83	Sorghum bicolor	O
ORYSJ\|EnsemblGenome=Os05g0182800\|UniProtKB=Q0DK87	Oryza sativa	O
SETIT\|EnsemblGenome=SETIT_000357mg\|UniProtKB=K3XEP0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G038100\|UniProtKB=C5XMK4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb121810\|UniProtKB=A0A1D6MID5	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb337800\|UniProtKB=B6UC34	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0185200\|UniProtKB=Q5VRX8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g05460v3\|UniProtKB=I1HCS5	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0237450\|UniProtKB=A0A8I6X522	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7B02G392800\|UniProtKB=A0A3B6SJE5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G132300\|UniProtKB=A0A3B6FIX9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G111500\|UniProtKB=A0A3B6EDY7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G476100\|UniProtKB=A0A3B6TRK1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G084000\|UniProtKB=A0A3B6LHE8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G489700\|UniProtKB=A0A3B6RR64	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G113800\|UniProtKB=A0A3B6GNX8	Triticum aestivum	LDO
NELNU\|Gene=LOC104602922\|UniProtKB=A0A1U8ADS0	Nelumbo nucifera	O
NELNU\|Gene=LOC104608516\|UniProtKB=A0A1U8AXN0	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110792416\|UniProtKB=A0A9R0INZ6	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0543551\|UniProtKB=A0A251T326	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0739101\|UniProtKB=A0A251RYH1	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800405130\|UniProtKB=A0A9R1UVZ6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a001563mg\|UniProtKB=A0A022RL83	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_26822\|UniProtKB=A0A2G2YC56	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400014572\|UniProtKB=M1B5V8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc05g009220.3\|UniProtKB=A0A3Q7GEE9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107791030\|UniProtKB=A0A1S3ZVZ9	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107775454\|UniProtKB=A0A1S3YF68	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi01g00303\|UniProtKB=D7T929	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi15g00533\|UniProtKB=D7SM09	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03004\|UniProtKB=A0A059D754	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P39220.1\|UniProtKB=A0A078HXQ7	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024759\|UniProtKB=M4E7K4	Brassica campestris	LDO
ARATH\|TAIR=locus=2032965\|UniProtKB=Q8W4F3	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107959926\|UniProtKB=A0A1U8PMM3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_032306\|UniProtKB=A0A061FGX0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g003751mg\|UniProtKB=A0A067GBB7	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_008G122200v3\|UniProtKB=A0A2K1ZFZ9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_06G066500\|UniProtKB=A0A2C9VNM2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_14G104300\|UniProtKB=A0A2C9UKN3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1309310\|UniProtKB=B9SLX3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_20G117100\|UniProtKB=I1NFK8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G272800\|UniProtKB=I1LEV4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g110430\|UniProtKB=G7ICA2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_02390\|UniProtKB=A0A2I4H0N6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G271450\|UniProtKB=A0A0A0LMF7	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_2G247610\|UniProtKB=A0A0A0LIR0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G313400\|UniProtKB=M5XLP3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_108529\|UniProtKB=D8S3R7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_78641\|UniProtKB=D8QV01	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_404079\|UniProtKB=D8QU78	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_168502\|UniProtKB=D8R589	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_19680\|UniProtKB=A9S2J6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0039s0055\|UniProtKB=A0A2R6X368	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001690020\|UniProtKB=A0A1Y1HZ43	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0311\|UniProtKB=A9A423	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_1075\|UniProtKB=B1L5U2	Korarchaeum cryptofilum	O
SACS2\|EnsemblGenome=SSO0093\|UniProtKB=P95968	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE2969\|UniProtKB=Q8ZU33	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_0587\|UniProtKB=Q8TT52	Methanosarcina acetivorans	O
METJA\|EnsemblGenome=MJ_1377\|UniProtKB=Q58772	Methanocaldococcus jannaschii	O
HALSA\|EnsemblGenome=VNG_1153G\|UniProtKB=Q9HQI1	Halobacterium salinarum	O
THEKO\|EnsemblGenome=TK1408\|UniProtKB=Q5JH16	Thermococcus kodakaraensis	O
CLOBH\|Gene_OrderedLocusName=CBO1094\|UniProtKB=A5I0T6	Clostridium botulinum	O
DEIRA\|EnsemblGenome=DR_2611\|UniProtKB=P56926	Deinococcus radiodurans	O
BACTN\|EnsemblGenome=BT_1325\|UniProtKB=Q8A849	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB1578\|UniProtKB=Q7UX42	Rhodopirellula baltica	O
NEIMB\|EnsemblGenome=NMB1560\|UniProtKB=P56927	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU3366\|UniProtKB=Q747A1	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC50102\|UniProtKB=Q89KR6	Bradyrhizobium diazoefficiens	O
HAEIN\|EnsemblGenome=HI_1354\|UniProtKB=P43831	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_1786\|UniProtKB=Q8EG26	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0997\|UniProtKB=Q9KTA6	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0821\|UniProtKB=Q8PCB3	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1794\|UniProtKB=Q9I2U8	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0686\|UniProtKB=Q8ZQX5	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_1084\|UniProtKB=Q8ZDD9	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35328\|UniProtKB=P00962	Escherichia coli	O