PANTHER Gene Information

Gene Symbol(s):

ears-2

Organism:

Caenorhabditis elegans

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Gene Name:

Probable glutamate--tRNA ligase, mitochondrial

Gene ID:

WBGene00001338

Protein ID:

O44413

Persistent Id:

PTN000012512

Alternate Ids:

CE34997(WormBase_PRO)	BX284604(EMBL)
NM_067516(refSeq)	O44413_CAEEL(UniProtKB-ID)
WBGene00001338(Ensembl)	T07A9(WormBase_TRS)
351064940(GI)	176860(GeneID)
CCD73973(EMBL-CDS)	WBGene00001338(WormBase)
O44413(Synonym)
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PANTHER Classification

PANTHER Family:	GLUTAMATE--TRNA LIGASE (PTHR43311)
PANTHER Subfamily:	GLUTAMATE--TRNA LIGASE, MITOCHONDRIAL-RELATED (PTHR43311:SF2)
PANTHER GO-slim Molecular Function:	catalytic activity, acting on RNA ligase activity
PANTHER GO-slim Biological Process:	amino acid metabolic process translation tRNA metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	aminoacyl-tRNA synthetase

Pathway Categories:

Heme biosynthesis

Glutamyl-tRNA-synthetase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	nucleotide binding, ATP binding, aminoacyl-tRNA ligase activity, glutamate-tRNA ligase activity, tRNA binding
GO BP Complete:	glutamyl-tRNA aminoacylation, tRNA aminoacylation, translation
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29419\|UniProtKB=Q5JPH6	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007887.6\|UniProtKB=H2QAR9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007365.3\|UniProtKB=A0A2I2ZVK8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000020525.4\|UniProtKB=A0A5F8AHU2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914667\|UniProtKB=Q9CXJ1	Mus musculus	LDO
RAT\|RGD=1307904\|UniProtKB=M0RAI4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000045593.2\|UniProtKB=G3N260	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010797.5\|UniProtKB=F1SAB4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014955.4\|UniProtKB=F7C4S4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005178.6\|UniProtKB=M3X6Q0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845001728.1\|UniProtKB=A0A8I3MJU3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006745.2\|UniProtKB=F7CD53	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009665.3\|UniProtKB=F6TQT9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017219.1\|UniProtKB=A0A8V0YTD4	Gallus gallus	O
CHICK\|Gene_ORFName=RCJMB04_20f12\|UniProtKB=Q5ZJ66	Gallus gallus	LDO
XENLA\|Gene=ears2.L\|UniProtKB=A0A1L8EY42	Xenopus laevis	O
XENLA\|Gene=ears2.S\|UniProtKB=A0A1L8EQK8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-970848\|UniProtKB=Q66JG3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010051.2\|UniProtKB=H2M2G6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060825-214\|UniProtKB=Q0P499	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004065.1\|UniProtKB=W5M904	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002621.3\|UniProtKB=F7B2R9	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_265112\|UniProtKB=C3YJE6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583633\|UniProtKB=A0A7M7NM25	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG13545\|UniProtKB=A8XI55	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00116891\|UniProtKB=A0A2A6D0N1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036629\|UniProtKB=Q9VV59	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002570\|UniProtKB=Q7QCD2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013887\|UniProtKB=A0A139WI37	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308493\|UniProtKB=E9G264	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016003\|UniProtKB=B7P652	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW009355\|UniProtKB=B7PZU6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG113813\|UniProtKB=T1EFX1	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG29866\|UniProtKB=B3S612	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_17829\|UniProtKB=A9URL2	Monosiga brevicollis	LDO
YEAST\|SGD=S000005393\|UniProtKB=P48525	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL338C\|UniProtKB=Q758U0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000186309\|UniProtKB=A0A1D8PSE8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E17919g\|UniProtKB=Q6C5H9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_07361\|UniProtKB=Q5AWG9	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G16280\|UniProtKB=Q4WZP0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00466\|UniProtKB=Q7RXX9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_03349\|UniProtKB=A7EDF9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_16120\|UniProtKB=Q0TWI3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAPB1A10.11c\|UniProtKB=Q9HDX9	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03071\|UniProtKB=B6K389	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNK01030\|UniProtKB=Q5K9R5	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10154\|UniProtKB=A0A0D1CTV5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_11523\|UniProtKB=E3KM05	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0271906\|UniProtKB=Q869Z3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_58973\|UniProtKB=F1A3S5	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_243640\|UniProtKB=A2FJ97	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1357200\|UniProtKB=Q8IDD3	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_38909\|UniProtKB=B8CGL5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HAW0_PHYRM\|UniProtKB=H3HAW0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g313700v5\|UniProtKB=A0A2K3DII9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00022p00146010\|UniProtKB=W1PNC9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_27G01290\|UniProtKB=A0A0K9PFS8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma08_g26230\|UniProtKB=A0A804KAX5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016776mg\|UniProtKB=K3YR82	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G018100\|UniProtKB=C5XT03	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb230310\|UniProtKB=A0A804PE79	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb208250\|UniProtKB=A0A804P4N5	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0121000\|UniProtKB=Q6YUS0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g01950v3\|UniProtKB=I1HWI9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0549780\|UniProtKB=A0A8I6YPR9	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G068300\|UniProtKB=A0A3B6QCY2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G094500\|UniProtKB=A0A3B6PII2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G070500\|UniProtKB=A0A3B6NKF5	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_016416\|UniProtKB=A0A1U8ARN3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110786632\|UniProtKB=A0A9R0ICR2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr16g0752951\|UniProtKB=A0A251SKE2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800437690\|UniProtKB=A0A9R1X0L6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003781mg\|UniProtKB=A0A022RCT3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_34417\|UniProtKB=A0A1U8E8C4	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc01g112290.3\|UniProtKB=A0A3Q7EUN5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107774917\|UniProtKB=A0A1S3YD67	Nicotiana tabacum	O
TOBAC\|Gene=SYE_TOBAC\|UniProtKB=Q43794	Nicotiana tabacum	O
TOBAC\|Gene=LOC107784556\|UniProtKB=A0A1S3ZA01	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi03g00260\|UniProtKB=D7U4Q0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H05005\|UniProtKB=A0A059B8J5	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A06P30760.1\|UniProtKB=A0A078I2F0	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra024262\|UniProtKB=M4E658	Brassica campestris	LDO
ARATH\|TAIR=locus=2164381\|UniProtKB=Q9FEA2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107900975\|UniProtKB=A0A1U8IW20	Gossypium hirsutum	O
GOSHI\|Gene=LOC107928970\|UniProtKB=A0A1U8LMM0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_007599\|UniProtKB=A0A061E2R9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g008289mg\|UniProtKB=A0A067FLS8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_009G169700v3\|UniProtKB=A0A2K1Z963	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G091600\|UniProtKB=A0A2C9WDT7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0281090\|UniProtKB=B9T2L7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G124000\|UniProtKB=K7L0Z1	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_03G097900\|UniProtKB=I1JME7	Glycine max	LDO
JUGRE\|EnsemblGenome=Jr13_10620\|UniProtKB=A0A2I4FCC3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G027880\|UniProtKB=A0A0A0K502	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G016800\|UniProtKB=M5VME3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_180792\|UniProtKB=D8SLI2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_172681\|UniProtKB=D8RME9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c1_10010\|UniProtKB=A0A2K1L7N5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0005s0181\|UniProtKB=A0A2R6XR19	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001300090\|UniProtKB=A0A1Y1I2H6	Klebsormidium nitens	LDO
DEIRA\|EnsemblGenome=DR_1687\|UniProtKB=Q9RTR9	Deinococcus radiodurans	O
RHOBA\|EnsemblGenome=RB13261\|UniProtKB=Q7UHE2	Rhodopirellula baltica	O
NEIMB\|EnsemblGenome=NMB0349\|UniProtKB=Q9K141	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU1329\|UniProtKB=Q74DI7	Geobacter sulfurreducens	O
BRADU\|Gene=gltX\|UniProtKB=Q89UN9	Bradyrhizobium diazoefficiens	O
SHEON\|Gene_OrderedLocusName=SO_0873\|UniProtKB=Q8EIG6	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0595\|UniProtKB=Q9KUC7	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2293\|UniProtKB=Q8P8E9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA4724\|UniProtKB=Q9HV75	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0185\|UniProtKB=Q8ZRQ7	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0287\|UniProtKB=Q8ZBL1	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAB96721\|UniProtKB=P27305	Escherichia coli	O
CHLAA\|EnsemblGenome=Caur_1535\|UniProtKB=A9WAX3	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO5547\|UniProtKB=O86528	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2992c\|UniProtKB=P9WFV9	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_462\|UniProtKB=P47700	mycoplasma genitalium	LDO
STRR6\|EnsemblGenome=spr1881\|UniProtKB=Q8CWN5	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00509\|UniProtKB=Q2G241	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAD00764\|UniProtKB=Q8YAB3	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_00920\|UniProtKB=P22250	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_0108\|UniProtKB=Q81J61	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1875\|UniProtKB=Q9X2I8	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_1351\|UniProtKB=Q9X172	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_0485\|UniProtKB=Q9RX30	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC90319\|UniProtKB=Q7NI06	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10429\|UniProtKB=Q55778	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_4190\|UniProtKB=Q8EYM3	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_2748\|UniProtKB=Q8A455	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB7600\|UniProtKB=Q7UNF9	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_1221\|UniProtKB=O67271	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A2003\|UniProtKB=B5YIG1	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1273\|UniProtKB=B8E0A6	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1340\|UniProtKB=Q8RDZ8	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0643\|UniProtKB=O25360	Helicobacter pylori	O
HELPY\|EnsemblGenome=HP_0476\|UniProtKB=P96551	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB0003\|UniProtKB=Q9K1R6	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1219\|UniProtKB=Q74DU6	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC50103\|UniProtKB=Q89KR5	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1488\|UniProtKB=Q83BL6	Coxiella burnetii	O
COXBU\|EnsemblGenome=CBU_0205\|UniProtKB=Q83EV3	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0274\|UniProtKB=P43818	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_3130\|UniProtKB=K4PSJ0	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2214\|UniProtKB=P0C6Q1	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2686\|UniProtKB=Q8P7C5	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3134\|UniProtKB=Q9XCL6	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2415\|UniProtKB=P0A2K3	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_2609\|UniProtKB=Q8ZCK0	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA16272\|UniProtKB=P04805	Escherichia coli	LDO