PANTHER Gene Information   
Gene Symbol(s): ADCY3
Organism: Homo sapiens
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Gene Name: Adenylate cyclase type 3
Gene ID: HGNC:234
Protein ID: O60266
Enhancers: View enhancers for HUMAN|HGNC=234|UniProtKB=O60266
Genetic Variant Annotation: Annoq
Persistent Id: PTN002484496
Alternate Ids:
ADCY3_HUMAN(UniProtKB-ID) Q9UDB1(AltAccession)
HGNC:234(HGNC) 62822238(GI)
CHEMBL3164(ChEMBL) 600291(MIM)
ADCY3(Synonym) 109(GeneID)
AF033861(EMBL) ADCY3(Symbol)
ENSG00000138031(Ensembl) AAD13403(EMBL-CDS)
NP_001307542(refSeq) 4.6.1.1 {ECO:0000250|UniProtKB:Q8VHH7}(EC)
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PANTHER Classification
PANTHER Family: ADENYLATE CYCLASE TYPE 1 (PTHR45627)
PANTHER Subfamily: ADENYLATE CYCLASE TYPE 3 (PTHR45627:SF30)  
PANTHER GO-slim Molecular Function: adenylate cyclase activity
PANTHER GO-slim Biological Process: adenylate cyclase-activating G protein-coupled receptor signaling pathway
PANTHER GO-slim Cellular Component: plasma membrane
PANTHER protein class: adenylate cyclase
Pathway Categories: Endothelin signaling pathway
   Adenylate cyclase
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
   Adenylyl cyclase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, calmodulin binding, metal ion binding, adenylate cyclase activity
GO BP Complete: cAMP biosynthetic process, flagellated sperm motility, acrosome reaction, signal transduction, cellular response to forskolin, sensory perception of smell, olfactory learning, adenylate cyclase-activating G protein-coupled receptor signaling pathway, single fertilization, intracellular signal transduction
GO CC Complete: cytoplasm, membrane, cilium, Golgi apparatus, ciliary membrane, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by Hedgehog, FCGR3A-mediated IL10 synthesis, Sensory Perception, Neuronal System, Opioid Signalling, Neurotransmitter receptors and postsynaptic signal transmission, Transmission across Chemical Synapses, Adenylate cyclase activating pathway, Infectious disease, Signaling by GPCR, ADORA2B mediated anti-inflammatory cytokines production, GABA receptor activation, Signal Transduction, Olfactory Signaling Pathway, GABA B receptor activation, Vasopressin regulates renal water homeostasis via Aquaporins, G alpha (s) signalling events, G alpha (z) signalling events, G alpha (i) signalling events, PKA activation, Glucagon signaling in metabolic regulation, GPCR downstream signalling, Leishmania parasite growth and survival, Calmodulin induced events, Adenylate cyclase inhibitory pathway, PKA-mediated phosphorylation of CREB, Hedgehog 'off' state, Activation of GABAB receptors, CaM pathway, Disease, Ca-dependent events, Anti-inflammatory response favouring Leishmania parasite infection, Leishmania infection, DAG and IP3 signaling, Metabolism, PLC beta mediated events, Integration of energy metabolism, PKA activation in glucagon signalling, G-protein mediated events, Aquaporin-mediated transport, Parasitic Infection Pathways, GPER1 signaling, Transport of small molecules, Intracellular signaling by second messengers

Orthologs