PANTHER Gene Information

Gene Symbol(s):

Pik3c2g

Organism:

Rattus norvegicus

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Gene Name:

Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma

Gene ID:

620231

Protein ID:

O70173

Persistent Id:

PTN000005713

Alternate Ids:

620231(RGD)	P3C2G(Synonym)
NM_053923(refSeq)	P3C2G_RAT(UniProtKB-ID)
3059227(GI)	2.7.1.137 {ECO:0000269\|PubMed:9516481}(EC)
116720(GeneID)	BAA25634(EMBL-CDS)
AB009636(EMBL)	Pik3c2g(Symbol)
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PANTHER Classification

PANTHER Family:	PHOSPHATIDYLINOSITOL KINASE (PTHR10048)
PANTHER Subfamily:	PHOSPHATIDYLINOSITOL 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA (PTHR10048:SF29)
PANTHER GO-slim Molecular Function:	lipid kinase activity phosphotransferase activity, alcohol group as acceptor
PANTHER GO-slim Biological Process:	cell migration phosphatidylinositol phosphate biosynthetic process phosphatidylinositol 3-kinase/protein kinase B signal transduction
PANTHER GO-slim Cellular Component:	phosphatidylinositol 3-kinase complex plasma membrane cytoplasm
PANTHER protein class:	kinase

Pathway Categories:

VEGF signaling pathway

Phosphatidylinositol 3-kinase

T cell activation

Phosphatidylinositol 3-kinase

Hypoxia response via HIF activation

Phosphatidylinositol 3-kinase

Insulin/IGF pathway-protein kinase B signaling cascade

Phosphatidylinositol 3-kinase

Inflammation mediated by chemokine and cytokine signaling pathway

Phosphatidylinositol 3-kinase

FGF signaling pathway

Phosphatidylinositol 3-kinase

Angiogenesis

Phosphatidylinositol 3-kinase

EGF receptor signaling pathway

Phosphatidylinositol 3-kinase

Integrin signalling pathway

Phosphatidylinositol 3-kinase

Axon guidance mediated by netrin

Phosphatidylinositol 3-kinase

Endothelin signaling pathway

Phosphatidylinositol 3-kinase

p53 pathway feedback loops 2

Phosphatidylinositol 3-kinase

p53 pathway

Phosphatidylinositol 3-kinase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, phosphatidylinositol binding, kinase activity, 1-phosphatidylinositol-4-phosphate 3-kinase activity, 1-phosphatidylinositol-3-kinase activity
GO BP Complete:	chemotaxis, phosphatidylinositol 3-kinase/protein kinase B signal transduction, phosphatidylinositol-mediated signaling, phosphatidylinositol-3-phosphate biosynthetic process, phosphatidylinositol phosphate biosynthetic process, modulation by host of viral process, cell migration
GO CC Complete:	nuclear envelope, cytoplasm, membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Phospholipid metabolism, Metabolism, Metabolism of lipids, Synthesis of PIPs at the Golgi membrane, Synthesis of PIPs at the plasma membrane, PI Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8973\|UniProtKB=O75747	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004741.5\|UniProtKB=A0A2J8QPU6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000017159.3\|UniProtKB=G3RLT6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022174.4\|UniProtKB=F6XHZ4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1203730\|UniProtKB=O70167	Mus musculus	LDO
BOVIN\|Ensembl=ENSBTAG00000020715.6\|UniProtKB=E1B8D1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000591.5\|UniProtKB=A0A5K1VBK6	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000000247.6\|UniProtKB=M3VUD0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018749.1\|UniProtKB=A0A8I3NWP1	Canis lupus familiaris	LDO
CHICK\|Ensembl=ENSGALG00010013617.1\|UniProtKB=A0A8V0YN62	Gallus gallus	LDO
XENLA\|Gene=LOC108712508\|UniProtKB=A0A1L8GQ56	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000045201\|UniProtKB=A0A803KDN3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029595.1\|UniProtKB=A0A3B3H7C6	Oryzias latipes	LDO
DANRE\|Gene=pik3c2g\|UniProtKB=A0A8M6Z287	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000023383.1\|UniProtKB=H2Y1I5	Ciona intestinalis	O
BRAFL\|Gene=LOC118414477\|UniProtKB=A0A9J7L1K4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC586734\|UniProtKB=A0A7M7P313	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00009552\|UniProtKB=G5EDY0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG07670\|UniProtKB=A8X4B6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095713\|UniProtKB=A0A2A6BJJ3	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0015278\|UniProtKB=Q7K3H0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011036\|UniProtKB=A0A1S4H5J3	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC034925\|UniProtKB=A0A139WAA5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_303261\|UniProtKB=E9FU84	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004026\|UniProtKB=B7PIF4	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022811\|UniProtKB=B7QET6	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90881\|UniProtKB=A7RRA6	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_28086\|UniProtKB=A9V757	Monosiga brevicollis	O
ENTH1\|EnsemblGenome=EHI_188970\|UniProtKB=C4M2W4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_006130\|UniProtKB=C4M2P7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_095130\|UniProtKB=C4M4S6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_040690\|UniProtKB=C4M5P0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_009890\|UniProtKB=C4M0Q4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_013980\|UniProtKB=C4LXN9	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0268548\|UniProtKB=Q55FX5	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38568\|UniProtKB=F0ZUR5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0291093\|UniProtKB=Q54F55	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_96754\|UniProtKB=F0ZAX6	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0283081\|UniProtKB=P54674	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_52203\|UniProtKB=F0Z7E7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282625\|UniProtKB=Q54S78	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_35373\|UniProtKB=F0ZP96	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0275011\|UniProtKB=P54675	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149892\|UniProtKB=F0ZEX7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0278727\|UniProtKB=P54673	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_58194\|UniProtKB=F0ZZM8	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_14855\|UniProtKB=A8B5J3	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_393100\|UniProtKB=A2DYA6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_344900\|UniProtKB=A2F0T8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_083340\|UniProtKB=A2DM61	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_284350\|UniProtKB=A2EN93	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_101460\|UniProtKB=A2DJM8	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00018694001\|UniProtKB=A0DN72	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019938001\|UniProtKB=A0DT78	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012877001\|UniProtKB=A0D2V1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027505001\|UniProtKB=A0EIN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039649001\|UniProtKB=A0DLV0	Paramecium tetraurelia	O
PHYRM\|Gene=H3GL97_PHYRM\|UniProtKB=H3GL97	Phytophthora ramorum	O
PHYRM\|Gene=H3GLA1_PHYRM\|UniProtKB=H3GLA1	Phytophthora ramorum	O
KLENI\|Gene_ORFName=KFL_003910060\|UniProtKB=A0A1Y1IAN1	Klebsormidium nitens	O